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10 Cards in this Set
- Front
- Back
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What does LTP stand for?
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Long-term potentiation
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What is the definition of LTP?
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It is a long-lasting increase in synaptic efficacy.
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The efficacy of synaptic transmission (increases/decreases) after a high-frequency stimulation.
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Increases
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LTP is most commonly studied in which part of the brain?
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Hippocampus
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What does the NMDA glutatmate receptor on the post-synaptic membrane do?
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allows a lot of calcium to come into the cell when the channel is opened
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The experiment in which mice are trained to find a fixed, hidden platform by using distal, spatial cues is called....
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Morris Water Mater Maze (MWM)
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Chronic use of addictive drugs affects which neurotransmitter?
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Dopamine
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In drug addiction, when does tolerance occur?
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It occurs when the organism no longer responds to the addictive drug in the way that it initially responded. A higher dose is needed to acheive the same initial response.
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Different addictive drugs have the (same/different) ultimate effect on the brain.
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Same. They all directly or indirectly enhance the amount of dopamine signaling, promoting addiction.
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What is drug addiction?
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It is a chronic, relapsing brain disease. It is characterized by compulsive drug-seeking behavior no matter the cost.
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