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8 Cards in this Set
- Front
- Back
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Phospholipid degradation
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The partial or complete breakdown ofphospholipids to produce FA, alcohol headgroups, glycerol
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Is released by phospholipase leading to prostagladin synthesis
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Arachidonic acid
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Relased from phospholipase C (phosphatidyl inositol)and are both secondary messangers
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Inositol 1,4,5-triphosphatase & diacylglycerol
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Obesity
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Increased Lepin production, but receptors are dysfunctional
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Tays-Sachs disease
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-Deficiency of Enzyme hexosaminidase A
-Principle storage substance: Ganglioside G -Mental retardation, blindness, cherry red spot on macula, death between second/third year |
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Gaucher's disease
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-Enzyme deficiency: Hexosaminidase A
-Principal storage substance: Glucocerebroside -Liver and spleen enlargement, erosin of long bones & pelvis, mental retardation in infantile form only |
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Niemann-Pick disease
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-Enzyme deficiency: Sphinogmyelinase
-Storage substance: Sphingomyelin -Liver and spleen enlargement, mental retardation |
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Respiratory Distress Syndrom
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Decreased amts of Lecithin (phosphotidylcholine)
Lecithin found in lung surfactant |
