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33 Cards in this Set

  • Front
  • Back

Glucose Structure

Fructose Structure

What type of bonds make oligo or poly saccharaides?
Glycosidic bonds
What does it mean when a sugar is an alpha or beta isomer?
C1-OH is linked
What do B-1,4 glycosidic bonds produce?
Cellulose. Long straight glucose chains.
Can animals make cellulose?
No
Name common disaccharides?
Maltose, sucrose, lactose
What does an alpha-1,4 linkage make?
Helical chain of glucose
What is the preferred fuel for some tissues?
Carbs
Glycolysis is it a conserved pathway?
Yes
How many steps are there in the glycolysis pathway?
10 steps
Ultimately, what will glycolysis give you?
2 Pyruvate and 2 ATP
What is the first step of glycolysis and what do you need to know?
Hexokinase, you go from Glucose to G-6P. You spend 1 ATP. Delta G = Big Negative
What is the second step of glycolysis and what do you need to know?
Phosphoglucose Isomerase. G-6P to F-6P. Delta G = small negative
What is the third step of glycolysis and what do you need to know?
Phosphofructokinase. F-6P to F-1,6-B-P. You spend 1 ATP. Delta G = Big negative
What are the reactions called in stage one of glycolysis?
Hexokinase, Phosphoglucose Isomerase, Phosphofructokinase.
What is the result of stage 2 of Glycolysis?
Hexose bisphosphate to 2 triose monophosphate.
What is the fourth step of glycolysis and what do you need to know?
Aldolase. F-1, 6-BP will change into DHAP and GAP. Delta G = Small negative
What is the 5th step of glycolysis and what do you need to know?
Triose phosphate isomerase. DHAP turns into GAP. Delta G = small positive
What are the reactions called in stage two of glycolysis?
Aldolase and Triose phosphate isomerase.
What is the end result of stage 3?
2 NADH produced, 4 ATP produced, and pyruvate production
What is the 6th step of glycolysis and what do you need to know?
Glyceraldehyde 3-phosphate dehydrogenase. GAP turns into 1,3-BPG. You go from NAD+ and Pi to NADH and H+. It is an ox-phos reaction. Oxidation = glyceraldehyde and exergonic. Phosphorylation = endergonic. Delta G = small negative
What is the 7th step of glycolysis and what do you need to know?
Phosphoglycerate Kinase. 1,3-BPG turns into 3-Phosphoglycerate. ADP to ATP. Excergonic part of reaction: Transfer of phosphate from 1,3-BPG. Delta G = small positive
What is the 8th step of glycolysis and what do you need to know?
Phosphoglycerate mutase. You go from 3 phosphoglycerate to 2 phosphoglycerate. It’s a rearrangement. Delta G = small positive
What is the 9th step of glycolysis and what do you need to know?
Enolase. 2 Phosphoglycerate turns into phosphenolpyruvate. You lose an H2O. Delta G = small negative
What is the 10th step of glycolysis and what do you need to know?
Pyruvate Kinase. Phosphenolpyruvate turns into pyruvate. ADP turns into ATP. Delta G = Big Negative
What does the hexokinase reaction require?
Mg2+
How does it allow the OH group to make the nucleophilic substitution?
It arranges the two substrates close enough for a reaction to occur
What are the kinase reaction in glycolysis?
Hexokinase, Phosphofructokinase, phosphoglycerate kinase, pyruvate kinase.
Is the phosphate on 1,3-BPG made by a kinase reaction?
No
So Phosphoglucose Isomerase is a multistep reaction. You only need to know how to draw the cyclic forms, but how does the reaction work?
The cyclic part is opened. You take a hydrogen off of one part of the molecule, you put it back in a different place, you close the molecule
What are the isomerase reactions?
Phosphoglucose isomerase, triose phosphate isomerase, phosphoglycerate mutase.
What do isomerases do?
Take a group from substrate and give it back to the same molecule in a different place