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10 Cards in this Set
- Front
- Back
Which statement about the role of pyridoxal-phosphate in
the mechanism of action of phosphorylase is correct? A. It acts as a general acid-base catalyst. B. It orients the glycogen substrate in the active site. C. It binds water at the active site. D. It interacts with an allosteric site. E. It donates a proton to the O-4 of the departing glycogen chain. |
A. It acts as a general acid-base catalyst.
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In the electron-transport chain, which two-electron carrier transfers to one-electron carriers?
A. Heme A B. iron-sulfur proteins C. NADH D. ubiquinol E. Cytochrome C |
D. ubiquinol
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Which component increases glycogen degradation by directly activating phosphorylase kinase?
A. Ca++ B. ATP C. AMP D. Adenylate cyclase E. Glycogen synthase |
A. Ca++
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Which of the following would not result from an increase in
epinephrine levels? A. An increase in glycogen degradation B. phosphorylation of glycogen synthase C. phosphorylation of protein kinase A D. inactivation of protein phosphatase 1 E. All of the above |
C. phosphorylation of protein kinase A
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How would glycogen synthase kinase 3 affect glycogen syn-
thase function? A. Increase the binding affinity for glucose-6-P B. Decrease the bindinfg affinity for UDP-glucose C. increase the rate of addition of glucose molecules to glycogen D. increase the Vmax of glycogen synthase E. None of the above |
B. Decrease the bindinfg affinity for UDP-glucose
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Which of the following statements is (are) true?
I) Protein kinase promotes glycogen synthesis by activating phosphorylase kinase; II) glycogen synthesis is regulated in part by glucose-6-P levels III) glucagon promotes glycogen synthesis IV) phosphorylation by protein kinase b of glycogen synthase kinase 3 activates glycogen synthesis A. II only B. II and III C. II and IV D. I only E. I, II and IV F. III only |
C. II and IV
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________binds to the _______ subunits of protein kinase A, releasing the ____ subunits, which are now enzymatically _______.
A. Ca++, catalytic, regulatory, active B. AMP, regulatory, catalytic, active C. cAMP, regulatory, catalytic, active D. ATP, catalytic, regulatory, inactive E. cAMP, catalytic, regulatory, active |
C. cAMP, regulatory, catalytic, active
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Place the following respiratory-chain components in their proper sequence with the first one having the lowest reduction potential.
A. NADH-Q reductase, ubiquinone, cytochrome C reductase, cytochrome c, cytochrome c oxidase B. NADH-Q reductase, cytochrome c, ubiquinone, cy- tochrome C reductase, cytochrome c oxidase C. ubiquinone, NADH-Q reductase, cytochrome C reduc- tase, cytochrome c, cytochrome c oxidase D. NADH-Q reductase, ubiquinone, cytochrome c oxidase, cytochrome c, cytochrome C reductase E. cytochrome c, NADH-Q reductase, cytochrome c oxi- dase, ubiquinone, cytochrome C reductase |
A. NADH-Q reductase, ubiquinone, cytochrome C reductase, cytochrome c, cytochrome c oxidase
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Cytosolic NADH electrons can be transported into the mi-
tochondrion via the glycerol phosphate shuttle. Identify the mitochondrial oxidant receiving the electrons in this process. A. ketoglutarate B. NAD+ C. NADH D. oxaloacetate E. FAD F. malate |
E. FAD
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The equation for the reduction of pyruvate by FADH2 is as follows:
Pyruvate + FADH2 -> Lactate + FAD For pyruvate/lactate, E=-185 mV and for FAD/FADH2, E=- 5 mV. Calculate the _G for the reaction (Faraday constant F = 96.485 kJ/mol/V). A. +34.7 kJ/mol B. -34.7 kJ/mol C. -36.7 kJ/mol D. -18.4 kJ/mol E. +36.7 kJ/mol |
A. +34.7 kJ/mol
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