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10 Cards in this Set
- Front
- Back
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Class I genes
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RNA pol I - rRNA (28s, 18s, 5.8s)
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Class II genes
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RNA pol II - mRNA and U1 & U2 snRNAs
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Class III genes
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RNA pol III - tRNAs, 5s rRNA and snRNAs
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TATA
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promoter at -25 to -35
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Initiator
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a degenerate consensus sequence surrounding the start site of transcription
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TATA-less and Inr-less
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GC rich island promoter, ~100nt upstream of the initiation start site
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Pol II promoter, class II
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enhancer - DNA seq containing several transcription factor binding sites that can activate transcrptn over long distances independently of their position and orientation relative to a gene
DNA bending can cause an enhancer that is far from the promoter, to interact with the transcrptn initiation copmplex |
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TFIID
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important transcription factor that binds to the TATA box (promoter)
this allows RNA pol II to then bind to the promoter (can't bind until TFIID does) TFIIH has helicase/ATPase activity |
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DNA binding prots bind where?
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helix-turn-helix
helix-loop-helix Zn fingers leucine zippers |
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Homeobox prots
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products of homeotic genes
belong to helix-turn-helix class also called Hox genes |
