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4 Cards in this Set
- Front
- Back
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what happens if glucose 6 phosphate builds up?
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hexokinase is inhibited.
glucose stops being trapped inside the cell |
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how is pyruvate dehydrogenase regulated?
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by phosphorylation.
it's INACTIVE when phosphorylated |
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what phosphorylates pyruvate dehydrogenase?
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PDH kinase
(makes PDH INACTIVE) influenced by ratio of acetyl CoA: CoA oxidising FA increases ratio, switches off PDH, lactase (lactic acid) produced |
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what de-phosphorylates pyruvate dehydrogenase?
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PDH phosphatase (makes PDH ACTIVE)
stimulated by high concentration of mitochondrial calcium |
