Biochem Test 1

Front 1

Allosteric proteins

Back 1

contain distinct regulatory sites and have multiple functioning sites and display cooperativity.

Front 2

Examples of covalent modification include

Back 2

phosphorylation. acetylation. ubiquination.

Front 3

The most common strategy(ies) for enzymatic regulation are:

Back 3

multiple enzyme forms, allosteric control, reversible covalent modification, and proteolytic activation

Front 4

An allosteric interaction between a ligand and a protein is one in which:

Back 4

the binding of a molecule to a binding site affects the binding properties of another site on the protein.

Front 5

In hemoglobin, the transition from T state to R state (low to high affinity) is triggered by:

Back 5

oxygen binding.

Front 6

The fundamental cause of sickle-cell disease is a change in the structure of:

Back 6

hemoglobin.

Front 7

A small molecule that decreases the activity of an enzyme by binding to a site other than the catalytic site is termed a(n):

Back 7

allosteric inhibitor.

Front 8

Allosteric enzymes:

Back 8

usually have more than one polypeptide chain.

Front 9

How do a nucleotide and a nucleoside differ?

Back 9

A nucleotide is a nucleoside with a phosphate ester linked at the sugar 5' residue.

Front 10

In the trinucleotide pApCpG, where is the free OH group?

Back 10

at the 3' end

Front 11

The feature(s) of DNA deduced by Watson and Crick included

Back 11

two antiparallel polynucleotide chains coiled in a helix around a common axis. the pyrimidine and purine bases lie on the inside of the helix. the bases are nearly perpendicular to the axis.

Front 12

A major component of RNA but not of DNA is:

Back 12

uracil.

Front 13

The difference between a ribonucleotide and a deoxyribonucleotide is:

Back 13

deoxy- has an –H instead of an –OH at C-2.

Front 14

The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA:

Back 14

join the 3' hydroxyl of one nucleotide to the 5' hydroxyl of the next.

Front 15

By definition, the 5' end of a DNA or RNA strand:

Back 15

has no nucleotide attached to the 5' hydroxyl.

Front 16

The DNA oligonucleotide abbreviated pATCGAC:

Back 16

has 6 phosphate groups.

Front 17

In a double-stranded nucleic acid, cytosine typically base-pairs with:

Back 17

guanine.

Front 18

For the oligoribonucleotide pACGUAC:

Back 18

the nucleotide at the 5' end has a phosphate on its 5' hydroxyl.

Front 19

The Watson-Crick base pairing scheme for an A–T base pair includes:

Back 19

a hydrogen bond between a keto oxygen and an extracyclic amino group.
a hydrogen bond between two ring nitrogen atoms.

Front 20

In the Watson-Crick structure of DNA, the:

Back 20

the two strands are antiparallel.

Front 21

In the Watson-Crick model of DNA structure:

Back 21

the distance between two adjacent bases in one strand is about 3.4 Å.

Front 22

In the Watson-Crick model of DNA structure (now called B-form DNA):

Back 22

the bases occupy the interior of the helix.

Front 23

In double-stranded DNA:

Back 23

the two strands have complementary sequences.

Front 24

Adenine, Purine

Back 24

What is the name of this nucleotide

Front 25

Guanine, Purine

Back 25

What is the name of this nucleotide?

Front 26

Cytosine, Pyrimidine

Back 26

What is the name of this nucleotide

Front 27

Uracil, Pyrimidine

Back 27

What is the name of this nucleotide

Front 28

Thymine, Pyrimidine

Back 28

What is the name of this nucleotide?

Front 29

A form, B form, Z form

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name the three froms of DNA

Front 30

Name the forces in DNA

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H bonds between bases, hydrophobic bases in the middle, phosphates near water, stacking of bases (Van der Waals)

Front 31

Functions of Nucleic Acids include:

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Information molecules (DNA, RNA), Energy Metabolism (ATP), Anabolism (UDP-Glucose),

Front 32

Ribose

Back 32

This is:

Front 33

Deoxyribose

Back 33

This is: