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15 Cards in this Set

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Transformation

(1)The conversion from a normal animal cell to a cancerous cell.(2) a change in genotype and phenotype due to the assimilation of external DNA is from a member of a different species, transformation results in horizontal gene transfer.

Bacteriophages

A virus that infect bacteria also called phage.

Phage

A virus that infects bacteria.

Double Helix

The form of the native DNA referring to its two adjacent antiparallel polynucleotide strands wound around an imaginary axis into a spiral shape

Semiconservative model

Type of DNA replication in which the replicated double Helix consists of one strand derived from the parental molecule and one newly made strand

Origins of replication

Site where the replication of DNA molecule begins consisting of a specific sequence of nucleotide repk

Replication folk

A y-shaped region on a replicating DNA molecule where the parental strands are being unwounded and new strands are being synthesized

DNA polymerase

An enzyme that catalyzes the elongation of new DNA by the addition of nucleotides to the 3' end of an existing chain. There are several different DNA polymerases ; DNA polymerase III and DNA polymerase I play major roles in DNA replication in E. coli

Leading strand

A new complimentary DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5' -->3' direction

Lagging strand

A discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5'-->3' direction away from the replication folk

DNA ligase

A linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of one DNA fragment to the 5' end of another DNA fragment (such as a growing DNA chain )

Primer

A short stretch of RNA with a dree 3' end, bound by complimentary base pairing to the template strand and elongated with DNA nucleotides during DNA replication

Primase

An enzyme that joins RNA nucleotides to make a primer during DNA replication using the parental DNA strand as a template

Helicase

An enzyme that untwists the double helix of DNA at replication forks, separating the two strands and making them available a template strands

Single strand binding protein

A protein that binds to the unpaired DNA strands during DNA replication, stabilizing them and holding them apart while they serve as templates for the synthesis of complementary strands of DNA