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53 Cards in this Set

  • Front
  • Back
Segregation
Two members of a gene pair segregate from each other in the formation of gametes. Half the gametes carry one allele and the other half carry the other
Independent assortment
Genes for different traits sort independently of one another in the formation of gametes
Character vs. Trait
Character: heritable feature that various among individuals

Trait: the variations of that feature
Incomplete Dominance
A form of inheritance in which one allele is not completely dominant over the other
Codominance
Both allele for a trait are dominant
Pleiotropy
One gene affects multiple, seemingly unrelated phenotypic traits
Epistasis
Consists of the effect of one gene being dependent on the presence of one or more modifier genes
Polygenic Inheritance
Multiple gene inheritance
Pedigree
The record of descent of an animal, showing it to be purebred
Recessive inherited disorder
Needs two genes to be present
Histone
Proteins found in eukaryotic cell nuclei that package and order DNA into structural units called nucleosomes
Nucleosomes
Basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around eight histone protein cores
Looped Domain
Present in bacterial chromosomes as a way of packaging a massive chromosome into a small space
Chromatid
Each of the two threadlike strands into which a chromosome divides longitudinally during cell division
Chargaff's Rules
State that DNA from any cell of all organisms should have a 1:1 ration of pyrimidine and purine bases and that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine
Rosalind Franklin
Helix
Watson and Crick
DNA model
DNA replication
Begins at origins of replication where two strands are separated, opening up a replication bubble

Free-floating nucleotides attach to parent rungs

Strands elongate
Proteins help
Origin of Replication
Where replication is initiated
Replication Bubble
A portion of the DNA molecule that has opened, providing a site for two replication forks
Replication fork
The point at which two strands of DNA are separated to allow replication of each strand
Helicase
Enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes
Single-stranded binding proteins
A class of protein they have been identified in both viruses and organisms from bacteria to humans
Topoisomerase
An enzyme that alters the supercoiled form of a DNA molecule
Primase
An enzyme involved in the replication of DNA, creates an rna primer
DNA polymerase I
Replicates the base sequence of a template DNA strand
DNA polymerase III
Prokaryotic
Dna ligase
Facilitates the joining of dna strands together by catalyzing the formation of a phosphodiester bond
Okazaki Fragments
Short, newly synthesized DNA fragments that are formed on the lagging template strand
Telomeres
Compound structure at end of chromosome
Why from genes to proteins
Genes contain coded formula needed by the cell to produce proteins.
Rna
Bridge between genes and proteins for which they code
mRNA
Carries messages in series of codons
tRNA
Translates message by transferring AA from cytoplasmic pool to a growing polypeptide chain
Codons
Flow of info from gene to protein is based on a triplet code
Reading frame
Correct groupings
Transcription
DNA-directed synthesis of rna
RNA POLYMERASE
Pries DNA strands apart and hooks together RNA nucleotides
Promoter
DNA sequence where RNA polymerase attaches
Terminator
DNA sequence signals stop
Transcription unit
Stretch of DNA that is transcribed
Three Stages of Transcription
Initiation
Elongation
Termination
Translation
RNA-directed synthesis of polypeptide
tRNA
Translator from nucleic acid codon to amino acid
Anticodon
Three nucleotides forming a unit of genetic code in a transfer RNA molecule
P Site
Holds tRNA THAT carries the growing polypeptide chain
A Site
Holds the tRNA THAT carries best amino acid to be added to chain
E Site
Exit site where discharged tRNAs leave the ribosome
Three important components of evolution by natural selection
Variation
Variation is heritable
Variation leads to differential survival and reproduction
5 agents of evolutionary change
Mutations
Genetic Drift
Gene flow
Non-random mating
Natural selection
Bottleneck/founders effect
Genetic Drift can cause big losses of genetic variation for small populations
Sexual Dimorphism
Distinct difference in size or appearance between sexes of an animal in addition to difference between sexual organs themselves
Main sources of genetic variation
Mutations. Gene flow