Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
general h20 characteristics contribute to anomalous behavior
|
higher than normal BP
higher than normal FP high heat capacity |
|
chemical species H30
|
hydronium ion
|
|
define the Equilibrium constant
|
relates individual ion concentrations to the concentration of the aqueous compound. This constant is a good measure of the amount of dissociation of the compound into its ionic components.
|
|
List the ways in which [H+] can influence biological systems
|
1. rate of enzyme rxns
2. membrane permeability 3. stability and native conformation of proteins and macromolecules 4. molecular transport rates through membranes, both charged and uncharged 5. absorption, transport, and metabolism of drugs; drugs have varying dissociation rates based on pH 6. Hydrophobicity or hydrophilicity |
|
What are the pKs of the bicarbonate and phosphate systems?
|
phos = 6.7
bicarb = 6.1 |
|
define acid and base as used in bio systems
|
acid= proton donor
base = proton acceptor |
|
write the henderson-hasselbalch equation, describe its utility to a physician
|
pH = pK + log [base]/[acid]
conveniant way to relate concentrations of each of the conjugated pairs to the pH of its environment |
|
what are the relative concentrations of conjugate acid/base when pH equals pK?
|
pH is = pK only when each conjugate pair are equal to each other
relative [conj acid] is equal to base when ph=pk relative [conj base] is equal to acid when ph = pk |