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20 Cards in this Set

  • Front
  • Back
replication fork
y shaped region where parental strands of DNA are being unwound
helicases
enzymes that untwist th edouble helix at replication forks, separating two parental strand and making available as template

do not initiate synthesis polynucleotide, only add nucleotides that already exist
single strand binding proteins
bind to unpaired DNA strands, stabilize them
topisomerase
helps relieve the extra twisting strain of head of replication fork by breaking, swiveling, and rejoining DNA strands
primer
initial nucleotide chain that is produced during DNA synthesis
primase
synthesizes primer, short strand RNA in DNA synthesis
DNA plymerase
catalyze synthesis of new DNA by adding nucleotides to pre existing chain
leadign strand
5'3' synthesized toward replication fork continuously
lagging strand
elongates 5'3' in fragments away from replication fork, discontinuously
okazaki fragments
fragments of lagging strand 5'3' direction away from replication fork, that are then added to DNA
DNA poll III
parental DNA as template, synthesizes new DNA strand by covalently adding nucleotides to 3' end of pre existing DNA strand or RNA primer
DNA pol I
removes RNA nucleotides of primer from 5' end and replaces them with DNA nucleotides
DNA ligase
joins 3/ end of DNA that replaces primer to rest of leading strand and joins Okazaki fragments of lagging strand
mismatch repair
enzymes move and relpace incorrectly paired nucleotides that have resulted from replication errors
nuclease
segment of the strand containing the damage is cut out by this DNA enzyme

gap then filled with nucleotides using undamaged strand as template
nucleotide excision repair
involved in filling in gaps of DNA

DNA polymerase & DNA ligase
character
observable & heritable feature
trait
one variant of genetic character
phenotype
physical and physiological traits of an organism, determined by genetic makeup
genotype
the genetic makeup of an organism