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9 Cards in this Set
- Front
- Back
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The acetyl group is carried on lipoic acid as |
a thioester |
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The activity of dihydrolipoamide acetyltransferase (E2) is inhibited when the concentration of of acetyl CoA is decreased. |
False |
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The activity of dihydrolipoamide dehydrogenase (E3) is inhibited by a high NADH/NAD+ ratio. |
True |
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The arrangement of subunits in the PDH(pyruvate dehydrogenase) complex ensures that ________. |
the product of one enzyme is delivered to the next in turn |
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The order of prosthetic groups as they act in the three proteins of the PDH(pyruvate dehydrogenase) complex is: |
E1: thiamine pyrophosphateE2: dihydrolipoamideE3: FAD |
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The pyruvate dehydrogenase complex is composed of three distinct enzymes. |
True (E1,E2,E3) |
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Which of the following causes pyruvate dehydrogenase kinase to catalyze the phosphorylation and inactivation of E1 in the pyruvate dehydrogenase complex? |
elevated concentrations of NADH and ATP |
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Which of the following coenzymes is required by E1 of the pyruvate dehydrogenase complex for catalytic activity? |
thiamine pyrophosphate |
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Which of the following coenzymes is required by the pyruvate dehydrogenase complex for reoxidation of E3? |
NAD+ |
