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35 Cards in this Set

  • Front
  • Back

Multicellular organisms depend on cell division for

Development from fertilized cells


Growth


Repair

Genome

All Dna in a cell

Chromosomes

Dna tightly packed in a cell

Somatic cells

Non reproductive cells with two sets of chromosomes, diploid

Gamete

Reproductive cells (sperm and egg)


Have half as many chromosomes as somatic, haploid

Chromatin

Eukaryotic chromosomes consisted of this... Complex of Dna and protein that condenses during cell division

Sister chromatids

Each duplicated chromosome has this...These separate during cell division


centromere
is the narrow "waist" of the duplicated chromosome, where the two chromatids are most closely attached
Mitosis,

Cytokinesis

the division of the nucleus

 the division of the cytoplasm

Meiosis
yields nonidentical daughter cells that have only one set of chromosomes, half as many as the parent cell (produces gametes)
The cell cycle consists
Mitotic (M) phase (mitosis and cytokinesis) Interphase(cell growth and copying of chromosomes in preparation for cell division)



Interphase (about 90% of the cell cycle) can be divided into subphases: G1 phase (first gap) S phase (synthesis) G2 phase (second gap)





Prophase

Chromosomes are condensing

Prometaphase

Chromosomes apparent, nuclear envelope fragments

Metaphase

Spindle complete, chromosomes attach to microtubles, chromosomes aligned along metaphase plate

Anaphase

sister chromatids seperate

Telophase

daughter nuclei form(Cytokinesis is well underway late in this phase)

centrosome
the microtubule organizing center of the cell
An aster
(a radial array of short microtubules) extends from each centrosome
kinetochores
During prometaphase, some spindle microtubules attach to the _______ of chromosomes and begin to move the chromosomes
metaphase plate
chromosomes are all lined up at the this, the midway point between the spindle’s two poles.
Nonkinetochore
microtubules from opposite poles overlap and push against each other, elongating the cell
a cleavage furrow in animal cell and a cell plate in plant cells
forms during cytokinesis
binary fission
Prokaryotes (bacteria and archaea) reproduce by a type of cell division
origin of replication
In binary fission, the chromosome replicates beginning here
cell cycle control system
The sequential events of the cell cycle are directed by a distinct _________, which is similar to a clock,



which has specific




Checkpoints




where the cell cycle stops until a go-ahead signal is received.

G0 (Gzero) phase
If the cell does not receive the go-ahead signal, it will exit the cycle, switching into a nondividing state.
cyclins and

cyclin-dependent kinases (Cdks)

Two types of regulatory proteins are involved in cell cycle control
MPF (maturation-promoting factor)
is a cyclin-Cdk complex that triggers a cell’s passage past the G2 checkpoint into the M phase
growth factors, external signals
proteins released by certain cells that stimulate other cells to divide



For example, platelet-derived growth factor (PDGF) stimulates the division of human fibroblast cells in culture

internal signal
An example is that kinetochores not attached to spindle microtubules send a molecular signal that delays anaphase
density-dependent inhibition
Another example of external signals in which crowded cells stop dividing
anchorage dependence
Most animal cells also exhibit this, in which they must be attached to a substratum in order to divide
transformation
A normal cell is converted to a cancerous cell.
benign tumor
If abnormal cells remain at the original site,
Malignant tumors
invade surrounding tissues and can

metastasize,


exporting cancer cells to other parts of the body, where they may form secondary tumors