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36 Cards in this Set

  • Front
  • Back
Excretory System
Regulates blood pressure, blood osmolarity, acid-base balance, and removal of nitrogenous wastes products
Role of Kidneys
Filter blood by producing urine
Parts of the Kidney
Cortex (outer layer), medulla (middle layer) and center renal pelvis (center layer)
Medulla
Middle part of the kidney that is very salty (high concentration of salt ions)
Kidney Portal Systems
Blood flows from the renal artery into afferent arterioles to form the glomeruli inside the Bowman’s Capsule (first capillary bed) Blood then leaves from the efferent arterioles to the vasa recta surrounded by the nephron (second capillary bed) leaving kidney through renal vein
Kidney Solute Movement
Filtration, secretion, and reabsorption
Filtration
The movement of solutes from the blood to the filtrate at Bowman’s capsule Rate of filtration determined by Starling forces
Starling forces
The hydrostatic and oncotic pressure differentials between the glomerulus and Bowman’s space
Secretion
The movement of solutes from the blood to filtrate anywhere other than Bowman’s capsule
Reabsorption
The movement of solutes from the filtrate into the blood
Proximal Convoluted Tubule (PCT)
Site of bulk reabsorption of glucose, amino acids, soluble vitamins, salt and water Site of secretion of hydrogen ions, potassium ions, ammonia, and urea
Descending Limb of the Loop of Henle
Permeable to water but not salt causing water to be reabsorbed from the filtrate as it descends into the highly “salty” medulla
Countercurrent Multiplier System
The maximal reabsorption of water due to the fact that the vasa recta and nephron flow in opposite directions as the filtrate in the loop of Henle
Ascending Limb of the Loop of Henle
Permeable to salt but not water allowing salt to be reabsorbed both passively (inner medulla) and actively (outer medulla)
Distal Convoluted Tubule (DCT)
Site of salt reabsorption and waste product excretion (DUMP the HUNK: H+, urea, NH3, K+)
Collecting Duct
Variable permeability and responsive to both aldosterone and antidiuretic hormone allowing reabsorption of the right amount of water depending on the body’s needs
Low Blood Pressure Kidney Responses
Aldosterone: increases sodium and water reabsorption in the DCT and collecting duct, increasing blood volume but not changing osmolarity Antidiuretic Hormone: increases permeability of collecting duct to water increasing water reabsorption resulting in increased blood volume and decreased osmolarity
Aldosterone
Steroid hormone regulated by the renin-angiotensin-aldosterone system
Antidiuretic Hormone
ADH or vasopressin Peptide hormone synthesized by the hypothalamys and released by the posterior pituitary
Kidney pH Moderating
When pH is too low, the kidneys excrete more hydrogen ions and increase reabsorption of bicarbonate into the blood When pH is too high, the kidneys can excrete more bicarbonate and increase reabsorption of hydrogen ions
Skin Major Layers
Hypodermis, dermis, and epidermis
Epidermis Layers
All called stratum: corneum, lucidum, granulosum, spinosum, basale (superficial to deep)
Stratum Basale
Contains stem cells that proliferate to form keratinocytes
Keratinocytes
Produce keratin to resist damage and protect
Stratum Granulosum
Where the keratinocytes nuclei are lost
Stratum Corneum
Most superficial layer with many thin layers to serve as barriers to invasions by pathogens and prevent loss of fluid and salt
Cells of the Epidermis
Keratinocytes, melanocytes, and Langerhans cells
Melanocytes
Produce melanin which protects the skin from DNA damage caused by ultraviolet radiation (sun)
Langerhans Cells
Special macrophages that serve as antigen-presenting cells in the skin
Dermis
Two layers: loose papillary layer and more dense reticular layer
Sensory Cells in the Dermis
Merkel cells (deep pressure and texture), free nerve endings (pain), Meissner’s corpuscles (light touch), Ruffini endings (stretch), and Pacinian corpuscles (deep pressure and vibration)
Hypodermis
Contains fat and connective tissue to connect the skin to the rest of the body
Role of Skin
Thermoregulation, protection, and prevention of dehydration and salt loss from the body
Thermoregulation Mechanisms
Sweating, vasodilation, piloerection, vasoconstriction, shivering, and insulation (from body fat)
Sweating
Heat is absorbed from the body through evaporation of water from sweat
Piloerection
Arrector pili muscles contract raising hair on body thus trapping a layer of heated air around the skin