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36 Cards in this Set
- Front
- Back
Excretory System
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Regulates blood pressure, blood osmolarity, acid-base balance, and removal of nitrogenous wastes products
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Role of Kidneys
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Filter blood by producing urine
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Parts of the Kidney
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Cortex (outer layer), medulla (middle layer) and center renal pelvis (center layer)
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Medulla
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Middle part of the kidney that is very salty (high concentration of salt ions)
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Kidney Portal Systems
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Blood flows from the renal artery into afferent arterioles to form the glomeruli inside the Bowman’s Capsule (first capillary bed) Blood then leaves from the efferent arterioles to the vasa recta surrounded by the nephron (second capillary bed) leaving kidney through renal vein
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Kidney Solute Movement
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Filtration, secretion, and reabsorption
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Filtration
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The movement of solutes from the blood to the filtrate at Bowman’s capsule Rate of filtration determined by Starling forces
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Starling forces
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The hydrostatic and oncotic pressure differentials between the glomerulus and Bowman’s space
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Secretion
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The movement of solutes from the blood to filtrate anywhere other than Bowman’s capsule
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Reabsorption
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The movement of solutes from the filtrate into the blood
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Proximal Convoluted Tubule (PCT)
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Site of bulk reabsorption of glucose, amino acids, soluble vitamins, salt and water Site of secretion of hydrogen ions, potassium ions, ammonia, and urea
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Descending Limb of the Loop of Henle
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Permeable to water but not salt causing water to be reabsorbed from the filtrate as it descends into the highly “salty” medulla
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Countercurrent Multiplier System
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The maximal reabsorption of water due to the fact that the vasa recta and nephron flow in opposite directions as the filtrate in the loop of Henle
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Ascending Limb of the Loop of Henle
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Permeable to salt but not water allowing salt to be reabsorbed both passively (inner medulla) and actively (outer medulla)
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Distal Convoluted Tubule (DCT)
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Site of salt reabsorption and waste product excretion (DUMP the HUNK: H+, urea, NH3, K+)
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Collecting Duct
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Variable permeability and responsive to both aldosterone and antidiuretic hormone allowing reabsorption of the right amount of water depending on the body’s needs
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Low Blood Pressure Kidney Responses
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Aldosterone: increases sodium and water reabsorption in the DCT and collecting duct, increasing blood volume but not changing osmolarity Antidiuretic Hormone: increases permeability of collecting duct to water increasing water reabsorption resulting in increased blood volume and decreased osmolarity
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Aldosterone
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Steroid hormone regulated by the renin-angiotensin-aldosterone system
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Antidiuretic Hormone
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ADH or vasopressin Peptide hormone synthesized by the hypothalamys and released by the posterior pituitary
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Kidney pH Moderating
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When pH is too low, the kidneys excrete more hydrogen ions and increase reabsorption of bicarbonate into the blood When pH is too high, the kidneys can excrete more bicarbonate and increase reabsorption of hydrogen ions
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Skin Major Layers
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Hypodermis, dermis, and epidermis
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Epidermis Layers
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All called stratum: corneum, lucidum, granulosum, spinosum, basale (superficial to deep)
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Stratum Basale
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Contains stem cells that proliferate to form keratinocytes
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Keratinocytes
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Produce keratin to resist damage and protect
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Stratum Granulosum
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Where the keratinocytes nuclei are lost
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Stratum Corneum
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Most superficial layer with many thin layers to serve as barriers to invasions by pathogens and prevent loss of fluid and salt
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Cells of the Epidermis
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Keratinocytes, melanocytes, and Langerhans cells
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Melanocytes
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Produce melanin which protects the skin from DNA damage caused by ultraviolet radiation (sun)
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Langerhans Cells
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Special macrophages that serve as antigen-presenting cells in the skin
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Dermis
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Two layers: loose papillary layer and more dense reticular layer
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Sensory Cells in the Dermis
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Merkel cells (deep pressure and texture), free nerve endings (pain), Meissner’s corpuscles (light touch), Ruffini endings (stretch), and Pacinian corpuscles (deep pressure and vibration)
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Hypodermis
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Contains fat and connective tissue to connect the skin to the rest of the body
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Role of Skin
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Thermoregulation, protection, and prevention of dehydration and salt loss from the body
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Thermoregulation Mechanisms
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Sweating, vasodilation, piloerection, vasoconstriction, shivering, and insulation (from body fat)
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Sweating
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Heat is absorbed from the body through evaporation of water from sweat
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Piloerection
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Arrector pili muscles contract raising hair on body thus trapping a layer of heated air around the skin
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