Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
120 Cards in this Set
- Front
- Back
- 3rd side (hint)
sensory receptors
|
detect & respond to a specific stimulus
-act as transducers - convert stimulus energy into changes in membrane potential -sensory information is communicated via action potentials carried by sensory neurons |
monitor specific conditions within body or in external environment:
arriving information is called a sensation awareness of a sensation is a perception |
|
Each receptor responds best to ______ of stimulus.
|
Each receptor responds best to a specific type of stimulus.
|
|
|
transduction
|
conversion of one form of energy into another
|
|
|
sensation
|
arriving information
|
|
|
perception
|
awareness of a sensation
|
|
|
general senses
|
pain, temperature, touch, pressure, vibration
|
|
|
special senses
|
olfaction (smell), vision (sight), gustation (taste), equilibrium (balance), and hearing
|
located in specific sense organs → structurally more complex
|
|
general senses receptors
|
throughout body, relatively simple structure; most cell processes (dendrites) that monitor conditions in body & environment
|
|
|
smaller receptive field =
|
more precise location
|
|
|
What are the classes of sensory receptors?
|
photoreceptors, mechanoreceptors, chemoreceptors, thermoreceptors, nociceptors
|
|
|
photoreceptors
|
light
|
|
|
mechanoreceptors
|
touch, pressure, stretch, vibration, sound, acceleration
|
use mechanically gated ion channels
|
|
chemoreceptors
|
monitor chemicals (taste, olfaction, pH O₂)
|
use chemically gated ion channels (ligand-gated)
|
|
thermoreceptors
|
warm, cold
|
|
|
nociceptors
|
pain
|
|
|
Sensory receptors produce _______ (depolarization or hyperpolarization) in response to sensory stimuli
|
Sensory receptors produce graded receptor potentials (depolarization or hyperpolarization) in response to sensory stimuli
-caused by opening/closing of ion channels |
greater the stimulus = greater the change in membrane potential
ADD MORE INFO |
|
sensory receptors can be:
|
modified nerve endings or separate sensory cells
|
|
|
What is an example of modified nerve endings
|
touch receptors in skin
|
|
|
What is an example of separate sensory cell
|
photoreceptors in the eye
|
|
|
sensory unit
|
1 sensory unit + all sensory receptors associated with it
-each sensory neuron is associated with one type of receptor |
|
|
receptive field
|
area of body supplied by 1 sensory neuron
- smaller receptive fields results in greater acuity (e.g. two point discrimination threshold) |
|
|
tonic receptors
|
non-adapting or slowly adapting
|
fairly constant response to sustained stimulus (e.g. muscle stretch receptors)
|
|
phasic receptors
|
rapidly adapting
|
respond to initial change in stimulus, then decrease response (e.g. olfactory receptors)
|
|
Sensory Pathways to CNS
|
First Order Neuron
sensory neuron (receptor) delivers sensation to CNS cell body located in dorsal root ganglion |
Second order neuron
axon of sensory neuron synapses on interneuron in CNS; from spinal cord/brainstem to thalamus Third order neuron if sensation is to reach our "awareness," the second-order neuron synapses on a third-order neuron in the thalamus and thalamus relays info to the cerebral cortex for "perception" |
|
Third order neuron
|
thalamus relays info to the cerebral cortex for "perception"
|
|
|
somatosensory cortex
|
(perception of somatic sensations) parietal lobe (postcentral gyrus)
|
|
|
visual cortex
|
(vision) occipital lobe
|
|
|
auditory cortex
|
(sound) temporal lobe
|
|
|
olfactory cortex
|
(smell) temporal lobe
|
|
|
gustatory cortex
|
(taste) parietal lobe
|
|
|
3 layers (tunics) of eye
|
fibrous, vascular, sensory
|
|
|
fibrous tunic
|
forms outermost coat of eye, composed of: opaque sclera and clear cornea
|
ADD MORE
|
|
vascular tunic
|
three regions:
choroid, ciliary body, iris |
ADD MORE
|
|
iris
|
2 smooth muscle layers
|
ADD MORE
|
|
sensory tunic
|
retina
|
neural tissue with photoreceptors (cells that detect light waves)
ADD MORE |
|
Internal cavities filled with ______.
|
Internal cavities filled with ______.
(vitreous humor and aqueous humor) |
|
|
vitreous humor
|
posterior cavity (clear gel) helps maintain shape
|
|
|
aqueous humor
|
anterior cavity (clear fluid) nourishment
|
|
|
lens
|
biconvex, transparent, flexible, avascular structure
|
ADD MORE
|
|
fovea centralis
|
region of retina where image focuses
|
highest density of cones (no rods)
|
|
optic disc
|
"blind spot" exit for optic nerve → no photoreceptors
|
|
|
Visual pathway
|
photoreceptors → bipolar cells → ganglion cells → optic nerve → crosses at optic chiasm → optic tracts → thalamus → visual cortex
|
|
|
6 extrinsic eye muscles →
|
allow eyes to follow a moving object while maintaining image on fovea centralis
|
|
|
visual acuity and astigmatism
|
light rays → bend (refraction) as they pass through convex cornea & lens
• passing from air to higher density structures (pass through slower) • cornea is fixed; shape of lens is adjustable |
concave and convex
|
|
concave
|
surfaces diverge light waves
|
|
|
convex
|
surfaces converge light waves to a focal point
|
|
|
emmetropia
|
• normal eye has good visual acuity (sharpness of vision)
• incoming light is sharply focused on fovea centralist of retina • lens inverts image on retina ∙ left side of visual field → projected only right side of retina ∙ upper portion of field → projected downward |
|
|
myopia
|
(nearsightedness) eyes are too long, light rays focus in front of retina
• individuals can see near; not far • corrected with a concave lens • tested for with Snellen chart |
|
|
snellen eye chart
|
tests for myopia
|
normal vision - person can read to line marked 20/20
20/40 vision - individual must stand 20 ft from line that normal person can see at 40ft |
|
hyperopia
|
(farsightedness) eye is too short light rays focus behind retina
• individuals can see far; not near • corrected with a convex lens |
|
|
astigmatism
|
visual defect produced by abnormal curvature of cornea or lens or irregularity on their surface
• vision is distorted & blurred • corrected with uneven lens • tested with an astigmatism chart |
|
|
accommodation
|
ability of eye to focus on objects at different distances
|
|
|
lens is flattened for distant vision →
|
ciliary muscles are relaxed & suspensory ligaments are taut
no PNS stimulation |
|
|
lens is more spherical for close-up vision →
|
ciliary muscles are contracted & suspensory ligaments are relaxed
PNS stimulation |
|
|
presbyopia
|
("old eyes") ability to lose focus on close objects decrease with age
• decline in elasticity of lens • tested by measuring the closest point at which an individual can focus clearly • e.g. 10 year old near pt of vision ~ 8cm; 70 year old ~ 100cm |
|
|
6 extrinsic eye muscles →
|
allow eyes to follow a moving object while maintaining image on fovea centralis
• 3 cranial nerves control muscles |
|
|
nystagmus
|
if tone of 1 muscle is weak or nerve is damaged → eye can drift slowly in 1 direction, followed by rapid movement in opposite direction to correct position
|
|
|
ophthalmoscope
|
used to observer posterior portion of eye
|
|
|
macula lutea
|
"yellow spot"
• no rods • fovea centralis - highest concentration of cones • optic disc - blind spot |
|
|
optic disc
|
blind spot
• area where axons of all ganglion cells gather to form optic nerve (no rods or cones) • normally we are unaware of blind spot → brain "fills in" missing visual field |
|
|
phototransduction
|
conversion of light energy into electrical signals
• carried out by rods and cones • outer segment - molecules in disks that absorb light • inner segment - nuclei & organelles • synaptic terminal - storage & releases of chemical messengers |
|
|
4 photoreceptor types
|
• 1 rod type
• 3 cone types ∙ blue cones ∙ red cones ∙ yellow cones |
|
|
photopigments
|
organic compounds that absorb light waves
•derivatives of rhodopsin |
|
|
rhodopsin
|
made of opsin (protein) bound to retinal (pigment) synthesized from vitamin A
|
|
|
retinal pigment
|
same in rods & cones
|
|
|
opsin
|
differs in each cone type
• opsin type within a cone determines which wavelength will be absorbed |
|
|
phototransduction
|
retinal can assume various 3-D shapes (called isomers)
• When bound to opsin - retinal is kinked (11-cis-isomer) • When pigment absorbs light - twists into different shape (all-trans isomer) • Retinal = activated → ultimately causes AP to be transmitted down optic nerve |
|
|
bleaching
|
rhodopsin breaks down into retinal & opsin
• regeneration requires ATP & takes time causes lingering visual impression |
|
|
afterimage
|
appears after "bleaching" of the visual pigment of affected receptors
|
|
|
Humans have _____ color vision
|
Humans have trichromatic color vision
• color vision → provided by stimulation of 3 cone types |
|
|
colorblindness
|
can be cause by:
|
Genetic defect in photopigments (typically red and green)
• located on X chromosome • more common in males (inherited by mother) • females would have to inherit from mother and father |
|
auditory system
|
responsible for hearing
|
|
|
vestibular system
|
responsible for balance or equilibrium
|
|
|
What are the two sensory systems?
|
auditory system and vestibular system
|
|
|
Both sensory systems (auditory and vestibular) rely on ___ to detect movement of fluid within the cavities of the ear
|
Both sensory systems (auditory and vestibular) rely on hair cells (mechanoreceptors) to detect movement of fluid within the cavities of the ear
-causes a receptor potential → afferent neuron → CNS |
|
|
Hair cells in the ___ detect vibration produced by sound waves
|
Hair cells in the cochlear detect vibration produced by sound waves
|
|
|
Hair cells in the ______ respond to acceleration (motion and gravity)
|
Hair cells in the vestibular system respond to acceleration (motion and gravity)
|
|
|
Tympanic membrane
|
(eardrum)
• thin connective tissue membrane that vibrates in response to sound • transfers sound energy to the middle ear ossicles • boundary between outer and middle ears |
|
|
What are components of the external ear?
|
tympanic membrane
|
|
|
What are components of the middle ear?
|
auditory tube, ear ossicles (malleus, incus, stapes), oval window, round window
|
|
|
Middle ear
|
small, air-filled cavity
flanked laterally by the eardrum; medically by the oval & round windows |
|
|
Auditory (eustachian) tube
|
connects middle ear with pharynx (or throat)
• helps maintain normal pressure in middle ear |
|
|
What are the ear ossicle?
|
malleus, incus, and stapes
|
|
|
Three ear ossicles
|
transmit vibratory motion of the eardrum to the oval window
|
|
|
oval window
|
thin membrane that separates air-filled middle ear from fluid filled inner ear
|
|
|
round window
|
thin membrane that separates air-filled middle ear from fluid filled inner ear
|
|
|
malleus
|
hammer
|
|
|
incus
|
anvil
|
|
|
stapes
|
stirrup
|
|
|
bony labyrinth
|
surrounds and protects membranous labyrinth
• channels worm way through temporal bone |
|
|
bony labyrinth is subdivided into:
|
vestibule
semicircular canals cochlea |
|
|
endolymph
|
within membranous labyrinth —> potassium-rich fluid
|
|
|
perilymph
|
between bony and membranous labyrinth —> similar to extracellular fluid (high in sodium, low in potassium)
|
|
|
cochlea
|
spiral bony tube, located withing temporal bone
|
|
|
cochlear duct
|
tube within cochlea, contains endolymph lies between 2 chambers:
|
vestibular duct and tympanic duct
|
|
vestibular duct
|
contains perilymph
|
|
|
tympanic duct
|
contains perilymph
|
|
|
vestibular membrane
|
separates vestibular duct & cochlear duct
|
|
|
basilar membrane
|
separates tympanic duct & cochlear duct
|
|
|
spiral organ
|
(organ of Corti) sensory organ for sound
|
• located on top of basilar membrane
• contains hair cells & overlying tectorial membrane |
|
tectorial membrane
|
attached to inner wall of cochlear duct
|
|
|
hair cells
|
stereocilia tips embedded within tectorial membrane
|
|
|
Sounds and Mechanism of Hearing
|
sound -
|
consists of waves of pressure through air or water
ADD MORE |
|
Hair Cilia
|
Stereocilia
|
tips embedded in tectorial membrane
ADD MORE |
|
Coding of Sound Intensity and Pitch in the Cochlea
|
pitch -
|
encoded based on which portion of the basilar membrane vibrates
ADD MORE |
|
volume
|
(intensity) encoded by the frequency of action potentials
|
|
|
semicircular canals
|
detect rotational acceleration
• 3 canals oriented in perpendicular planes to detect 3-dimensional motion |
|
|
vestibule
|
2 components
|
utricle & saccule
ADD MORE |
|
cupula
|
gelatinous membrane, bends hair cells when fluid moves in semicircular ducts
|
ADD MORE HERE
|
|
Utricle and Saccule
|
otoliths
|
"ear stones" attached to membrane, bend hair cells when head moves
|
|
utricle
|
detect forward & backward accleration
|
|
|
saccule
|
detect up and down linear acceleration
|
|
|
conduction deafness
|
middle ear damage (e.g. middle ear infection, ossification of bones)
|
|
|
sensory deafness
|
cochlea or vestibulocochlear damage (e.g. infections, prolonged exposure to loud sounds)
|
|
|
Tuning Fork Tests:
|
Rinne's Test and Weber's Test
|
Vibrations from tuning fork are transmitted through skull bones to fluid in cochlea
|
|
Weber's Test
|
tuning fork placed on midsagittal line
|
• sound seems louder in conduction deaf ear
∙ cochlear hair cells are stimulated but room noise is excluded ∙ can stimulate with cotton in ear • sound is louder in normal ear in sensory deafness |
|
Rinne's Test
|
tuning fork placed on mastoid process; when sound is gone → place near external ear
|
• if sound re-appears (=no damage to middle ear/conduction deafness)
• put cotton in ear for 2nd test to stimulate conduction deafness |
|
Equilibrium
|
Afferent impulses from vestibular apparatus:
|
• make us aware of our position in space
• affect efferent somatic motor nerves (e.g. voluntary extrinsic eye muscles) |
|
vestibular nystagmus
|
involuntary eye oscillations produced by vestibular activity's affect on extrinsic eye muscles
|
|
|
test with swivel chair
|
note: after ~ 20 seconds of rotation →
|
fluid in semicircular canals has stabalized
• if abruptly stop → causes fluid to move again (activated response) |