Bio 2117 Exam 4

Front 1

Which of the following may be inherited from HIV infection?
a) Immunologic enhancement
b) Immunologic surveillance
c) Immunotherapy
d) Immunodeficiency

Back 1

Immunodeficiency

Front 2

For which of the following hypersensitivity reactions are sensitived T cells responsible?
a) Tuberculin skin test
b) Contact dermatitis
c) Reaction to poison ivy
d) Transplant rejection
e) All of the above

Back 2

All of the above

Front 3

LYSOZYME protects the skin and mucous membranes from infection by:
a) Stimulating antibody productions
b) Mechanically flushing organisms
c) Killing bacteria
d) Preventing adhesions of organisms
e) None of the above

Back 3

Preventing adhesion s of organisms

Front 4

The VARIABLE PORTIONS of the H and L chains of an antibody determine:

Back 4

The antigen (epitope) to which the antibody binds

Front 5

In systemic lupus erythematous, IgM, IgG, and deposit in the kidney. This is an example of

Back 5

Immune Complex Autoimmunity

Front 6

IgE antibodies are assocaited with the immune response to

Back 6

Large Parasites

Front 7

The antibodies found in mucus, salvia, and tears are

Back 7

IgA

Front 8

Monocytes give rise to which of the following?
a) Basophil
b) Lymphocytes
c) Macrophages
d) Neutrophil
e) Eosinophil

Back 8

Macrophages

Front 9

Anaphylactic shock is an example of what type of hypersensitivity?

Back 9

Type I

Front 10

In an immunodiffusion test to diagose the fungal disease histoplasmosis, patient's serum is placed in a well in an agar plate. In a positive test, a precipitate forms as the serum diffuses from the well and meets material diffusing from a second well.

What immunodiffusion test is described?

Back 10

An ELISA Test

Front 11

Cytokines released by TH1 cells:
a) activate CD8 cells to CTLs
b) convert TH1 to TH2 cells
c) kill parasites
d) convert TH2 to TH1 cells
e) convert B cells to T cells

Back 11

Convert B cells to T cells

Front 12

The classical pathway of the complement protein cascade is initiated by activation of ?

Back 12

C3

Front 13

What type of vaccine contains purified antigens?
a) Conjugated vaccine
b) Subunit vaccine
c) Nucleic Acid vaccine
d) Inactive whole-agent vaccine
e) Toxoid vaccine

Back 13

Subunit vaccine

Front 14

Which of the following exhibits no phagocytic activity?
a) Neutrophils
b) Dendritic Cells
c) Lymphocytes
d) Macrophages
e) All the above cells have phagocytic activity

Back 14

All the above cells have phagocytic activity

Front 15

VACCINES commonly include all the following except:
a) Parts of bacteria cells
b) Antibodies
c) Live, attenuated bacteria
c) Inactivated viruses
d) Inactivated toxoin

Back 15

Parts of bacteria cells

Front 16

Live microorganisms can be used in a(n)?

Back 16

Attenuated whole-agent vaccine

Front 17

Inflammation is characterized by:
a) Redness
b) Pain
c) Local Heat
d) Swelling
e) All of the above

Back 17

All the Above

Front 18

Type II hypersensitivity reactions are also known as

Back 18

Cytotoxic reactions

Front 19

Virus-infected cells are destory by?

Back 19

TH

Front 20

A reaction between antibody and particulate antigen is called a(n)?

Back 20

Immunofluorescence

Front 21

All of the following are advantages of live vaccine EXCEPT:
a) The live vaccine may revert to a more virulent form.
b) Produces both humoral and cell-mediated immunity
c) Produces memory cells
d) Produces long lasting immunity
e) None of the above are advantages

Back 21

The live vaccine may revert to more virulent form

Front 22

A substance that elicits an antibody response and can combine with those antibodies is called?

Back 22

An Immunestimulant

Front 23

Multiple sclerosis is the result of?

Back 23

Acquired immunodeficiency

Front 24

Which of the following is an example of naturally aquired passive immunity?
a) Innate Immunity
b) Immunity due to vaccination
c) Immunity due to the transfer of antibodies across the placenta
d) Immunity due to exposure to the disease
e) Immunity due to to injection of antibodies

Back 24

Immunity due to exposure to the disease

Front 25

Opsonization results in

Back 25

Increase diapedesis of phagocytes

Front 26

Mucus and any microorganisms trapped in it are removed from the lower respiratory tract by

Back 26

The ciliary escalator

Front 27

Which of the following describes a cytotoxic autoimmune reaction such as occurs in Graves disease?
a) Antibodies react to cell-surface antigens
b) Medaited by T cells
c) Cells are killed
d) Immune complexes form
e) Antibodies are not made

Back 27

Cells are killed

Front 28

What of the following statements is true?
a) Alpha-interferon acts against specific viruses
b) Alpha-interferon is an antiviral protein
c) Gamma-interferon causes cell lysis
d) Beta-interferon attacks invading viruses
e) Alpha-interferon promotes phagocytosis

Back 28

Gamma-interferon causes cell lysis

Front 29

Which of the following is most useful in screening patients for HIV infection, due to its high sensitivity?
a) ELISA
b) Fluorescent antibody
c) Complement fixation
d) Agglutination
e) Neutralization

Back 29

Fluorescent antibody

Front 30

Normal microbiota provide protection from infection by all of the following EXCEPT:
a) they make the chemical environment unsuitable for non resident bacteria
b) They provide antibacterial chemicals
c) They produce lysozyme
d) They out-compete newcomers
e) Non of the above

Back 30

They out-compete newcomers

Front 31

What is the first line of defense (Innate Immunity)?

Back 31

* Intact Skin
* Mucous membranes and their secretions
* Normal microbiota

Front 32

What is the second line of defense (Innate Immunity)?

Back 32

* Natural killer cells and phagocytic white blood cells
* Inflammation
* Fever
* Antimicrobial substances

Front 33

What is the third line of defense (Acquired Immunity)?

Back 33

* Specialized lymphocytes: T cells and B cells
* Antibodies

Front 34

What are the physical factors in first line of defense?

Back 34

* Epidermis * Mucous Membranes
* Mucus *Lacrimal Apparatus
* Saliva * Hairs
* Cilia *Epiglottis
* Urine Vaginal Secreions
* Defecations & Vomiting

Front 35

What are the chemical factors in first line of defense?

Back 35

* Sebum
* Lysozyme
* Gastric Juice
* Vaginal Secretions

Front 36

What are the 4 types of antimicrobial substances?

Back 36

*complement system
*interferons
*transferrins
*antimicrobals peptides

Front 37

Define Complement System:

Back 37

causes cytolysis of microbes, promotes phagocytosis & contribes to inflammation

Front 38

Define Interferons:

Back 38

protect the infected host cells from viral infection

Front 39

Define transferrins:

Back 39

inhibit growth of certain bacteria by reducing the amount of available iron.

Front 40

Define Antimicrobals Peptide:

Back 40

cause lysis of bacteria