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16 Cards in this Set

  • Front
  • Back
Activation Energy (Ea)
the initial investment of energy for starting a reaction;

the energy required to break the bonds of the reactants
Catalysts
chemical agents that speed the rate of a chemical reaction without being consumed or changed
How are catalysts thought to work?
By lowering the activation energy needed for a reaction to occur.
Most catalysts in organisms are made up of what?
Enzymes (proteins)
What is ribozyme?
RNA acting as a catalyst for a few biochemical reactions
Structure of Enzymes:
Globular proteins.
Simple or conjugated.
Depending on the relative concentration of reactants and products, Enzymes can...
...catalyze a reaction in either direction.

It does not determine the direction
What are substrates?
Reactants in enzyme catalyzed reactions
Enzymes differ in _____?
specificity
2 specificities of enzymes and corresponding meaning
Very specific- only catalyze one specific type of reaction. (eg urease)

Non-specific -- will catalyze several different, but very similar reactions (eg lipase)
Enzymes work primarily based on their _____?
3D shape, which is distinctive for each type of enzyme.
What is the active site of an enzyme?
Portion of an enzyme that interacts with a substrate
2 theories of active site and substrate fit, and their differences?
Lock and Key model- enzyme won't change shape.

Induced-fit model (most common) - Enzyme changes shape temporarily
3 ways enzymes may help speed up a reaction
Bringing substrates close together.
Orient substrates correctly for reaction.
Weaken bonds in substrate so they will break.
3 Environmental factors that affect enzyme reaction rate
Temperature
pH
Inhibition
2 types of Inhibitors and their meaning
Competitive - very similar in structure to the normal substrate; they compete with the normal substrate for binding to the active site.


Non-competitive -- do not resemble the structure of the normal substrate; bind to the allosteric site and change the shape of the enzyme and its active site