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53 Cards in this Set
- Front
- Back
hormone
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chemical signal that is secreted into the circulatory system and communicates regulatory messages within the body
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nervous system
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Conveys high-speed electrical signals along specialized cells called neurons
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endocrine system
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Secretes hormones that coordinate slower but longer-acting responses to stimuli
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neurosecretory cells
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Specialized nerve cells
-Release neurohormones into the blood -long-distance regulators of many physiological processes |
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control pathways
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Is a feedback loop connecting the response to the initial stimulus
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negative feedback
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Regulates many hormonal pathways involved in homeostasis
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signaling
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Reception
Signal transduction Response |
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The receptors for most water-soluble hormones
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Are embedded in the plasma membrane, projecting outward from the cell surface
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Binding of a hormone to its receptor
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Initiates a signal transduction pathway leading to specific responses in the cytoplasm or a change in gene expression
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epinephrine
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Has multiple effects in mediating the body’s response to short-term stress
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Steroids, thyroid hormones, and the hormonal form of vitamin D
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Enter target cells and bind to specific protein receptors in the cytoplasm or nucleus
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protein receptor complexes
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act as transcription factors in the nucleus, regulating transcription of specific genes
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paracrine signaling
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Various types of chemical signals elicit responses in nearby target cells
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Local regulators
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Neurotransmitters
Cytokines and growth factors Nitric oxide Prostaglandins |
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prostaglandins
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help regulate the aggregation of platelets
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hypothalmus
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hormones released form the posterier pitituary that regulate anterior pitutary
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oxytocin
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stimulates contraction of uterus and mammary gland cells
-regulated by nervous system |
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antiduretic hormone (ADH)
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retention of water by kidneys
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growth hormone (GH)
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promotes growth
-hypothalmic hormone |
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prolactin (PRL)
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stimulates milk production and secretion (hypothalmic)
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follicle stimulating hormone (FSH)
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stimulates production of ova and sperm (hypothalmic)
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lutinizing hormone (LH)
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stimulates ovaries and testes (hypothalmic)
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thyroid stimulating hormone (TSH)
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stimulates thyriod gland
-thyroxin in blood -hypothalmic |
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adrenocorticotropic hormone (ACTH)
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stimulates adrenal cortex to secret glucocorticoids
(hypothalmic) |
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T3, T4
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stimulates and maintains metabolic processes (TSH)
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calcitonin
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lowers blood calcium level
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parathyroid hormone
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raises blood calcium level
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insulin
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lowers blood glucose
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epindephrine and norepiniphrine
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raise blood glucose; constrict blood vessles
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androgens
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support sperm formation, secondary sex characteristics
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progesterine
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promote uterine lining growth
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anterior pituitary
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Is a true-endocrine gland
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The tropic hormones
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Control release of hormones from the anterior pituitary
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nontropic hormones
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Prolactin
Melanocyte-stimulating hormone (MSH) -endorphin |
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endorphins
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Inhibit the sensation of pain
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Nonpituitary hormones
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help regulate metabolism, homeostasis, development, and behavior
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thyroid gland
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Consists of two lobes located on the ventral surface of the trachea
Produces two iodine-containing hormones, triiodothyronine (T3) and thyroxine (T4) |
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Hyperthyroidism
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excessive secretion of thyroid hormones
Can cause Graves’ disease in humans |
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islets of Langerhans
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antagonistic hormones that help maintain glucose homeostasis and are found in clusters
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glucagon
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Is produced by alpha cells
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insulin
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Is produced by beta cells
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Insulin reduces blood glucose levels by
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Promoting the cellular uptake of glucose
Slowing glycogen breakdown in the liver Promoting fat storage |
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Glucagon increases blood glucose levels by
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Stimulating the conversion of glycogen to glucose in the liver
Stimulating the breakdown of fat and protein into glucose |
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Diabetes mellitus (endocrine disorder)
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Is caused by a deficiency of insulin or a decreased response to insulin in target tissues
Is marked by elevated blood glucose levels |
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type 1 diabetes (insulin dependent)
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Is an autoimmune disorder in which the immune system destroys the beta cells of the pancreas
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type 2 diabetes (non-insulin dependent)
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Is characterized either by a deficiency of insulin or, more commonly, by reduced responsiveness of target cells due to some change in insulin receptors
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adrenal glands
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Are adjacent to the kidneys
Are actually made up of two glands: the adrenal medulla and the adrenal cortex |
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adrenal medulla
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secretes epinephrine and norepinephrine
Hormones which are members of a class of compounds called catecholamines -Are secreted in response to stress-activated impulses from the nervous system |
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testostorone
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causes an increase in muscle and bone mass
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pineal gland
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located within the brain
Secretes melatonin -Appear to be related to biological rhythms associated with reproduction |
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brain hormone
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Is produced by neurosecretory cells
Stimulates the release of ecdysone from the prothoracic glands |
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ecdysone
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Promotes molting and the development of adult characteristics
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juvinile hormone
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Promotes the retention of larval characteristics
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