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49 Cards in this Set
- Front
- Back
Components of the Plasma Membrane (4)
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I. Phopholipid bilayer
II. Proteins III. Carbohydrates IV. Cholesterol (animals) |
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What is the name of the layers of the phospholipid bilayer called?
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Leaflets
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What is the outward leaflet called?
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Exoplasmic leaflet
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What is the inward leaflet called?
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Cytoplasmic leaflet
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What are the functions of the membrane proteins? (6)
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I. Transport proteins
II. Enzymes III. Receptors IV. Cell Adhesion Protein V. Cell Surface markers VI. Cytoskeleton attachment site |
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What do the Cell Surface markers do for the cell?
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A. Identify Cell Types (cell recognition)
B. Self vs. Non-self (white blood cells) |
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What was the function of the membrane carbohydrates? (3)
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I. Cell recognition
II. Cell coat (glycocalyx) -protects from harsh environments (stomach) and mechanical abrasions (mouth) III. Determines ABO blood types |
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What were the 3 movements of the membrane lipids?
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I. Lateral Diffusion
II. Flexion III. Flip Flop |
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Why are Flip Flops needed?
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Lipids are only added to the cytoplasmic leaflet and flip flops are needed to get the lipids exoplasmic leaflet
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What influences membrane fluidity? (3)
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I. Temperature
II. Saturated vs Unsaturated III. Cholesterol (animals) |
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How does temperature affect fluidity?
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Higher temp - increased fluidity
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How does saturated vs unsaturated fatty acid tails affect fluidity?
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More saturated - decreased fluidity
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How does cholesterol affect the fluidity?
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More cholesterol - decreased fluidity
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How does the membrane stay fluid at low temperatures? (4)
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I. Desaturation
II. Reshuffling III. Alter phospholipid synthesis IV. Increased cholesterol content (animals) |
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How does desaturation help fluidity?
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Creates double bonds to increase fluidity
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How does reshuffling help fluidity?
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Reshuffling the fatty acid tails so the bent tails are on the same polar head
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How does altering the phospholipid synthesis help fluidity?
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Favors synthesis of unsaturated phospholipids
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How does the cholesterol help fluidity?
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Increase cholesterol content seen in hibernating animals
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Two forms of bulk transport
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I. Endocytosis
II. Exocytosis |
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What's the general mechanism of endocytosis?
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Involves invagination of the plasma membrane which removes a portion of the membrane
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What are the three forms of endocytosis?
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I. Phagocytosis
II. Pinocytosis III.Receptor mediated endocytosis |
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What does Pinocytosis do?
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Ingests liquids and dissolved substances
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What does Phagocytosis do?
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Ingests large matter
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What does receptor mediated endocytosis do?
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Ingests specific substances by target molecules attaching to receptors an the pit folding in on itself
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Define exocytosis
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Excretion of substances
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What's the general mechanism of exocytosis?
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secretory vesicles merge with membrane and release materials out of the cell
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How does selective transport occur? (2)
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I. Directly through membrane
II. Through transport proteins |
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What molecules can pass directly through the membrane?
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-Very small
-Small uncharged and polar molecules |
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What molecules can't pass through the membrane?
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-Very large
-Ions |
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Two types of membrane transport proteins
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I. Channel protein
II. Carrier protein |
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What are the properties of membrane transport proteins? (3)
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I. Selective
II. Mostly Ion Channels III. Gates regulate amount |
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What's the general mechanism of carrier proteins?
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Changes shape to allow molecules through
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What are three types of carrier proteins?
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I. Uniport
II. Symport III. Antiport |
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Define Uniport
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Transports one substance in one direction
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Define symport
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2 substances in one direction
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Define antiport
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2 substances in opposite directions
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What group is symport and antiport a part of?
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Coupled transport
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Define ATP
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energy source
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Define ATPase
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enzyme that hydrolyzes ATP which releases energy
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What are the steps for Na+/K+ ATPase?
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1. 3 Na+ bind
2. ATP binds 3. ATP hydrolysis 4. Shape change and release of Na+ 5. Potassium binds 6. Dephosphorylation 7. Release 2 K+ |
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What are the 3 important things of ATPase cycle?
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I. Establishes Na+ gradient to drive active transport
II. Establishes membrane potential III. Raises ion concentration and causes water to leave the cell |
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Define osmosis
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diffusion of water across a selective membrane
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2 ways water diffuses through a membrane
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I. Directly through (limited)
II. Channel proteins (aquaporins) |
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3 ways animal cells are affected by osmosis
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I. Hypertonic (shrivel cell)
II. Isotonic (normal cell) III. Hypotonic (burst cell) |
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Why don't Hypotonic enviroments affect plants?
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Cell wall prevents excessive uptake of water
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How does a hypertonic enviroment affect plants?
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Causes central vacuole to pull away from the cell wall
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Define osmoregulation
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control of water balance
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3 ways to counter excessive water uptake
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I. Live in isotonic environment
II. Bathe cell in isotonic fluid (blood) III. Special adaptions |
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What are 3 special adaptions?
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I. Less permeable plasma membrane
II. Contractile vacuole that stores water and discharges it outside the cell when full |