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49 Cards in this Set

  • Front
  • Back
Components of the Plasma Membrane (4)
I. Phopholipid bilayer
II. Proteins
III. Carbohydrates
IV. Cholesterol (animals)
What is the name of the layers of the phospholipid bilayer called?
Leaflets
What is the outward leaflet called?
Exoplasmic leaflet
What is the inward leaflet called?
Cytoplasmic leaflet
What are the functions of the membrane proteins? (6)
I. Transport proteins
II. Enzymes
III. Receptors
IV. Cell Adhesion Protein
V. Cell Surface markers
VI. Cytoskeleton attachment site
What do the Cell Surface markers do for the cell?
A. Identify Cell Types (cell recognition)
B. Self vs. Non-self (white blood cells)
What was the function of the membrane carbohydrates? (3)
I. Cell recognition
II. Cell coat (glycocalyx)
-protects from harsh environments (stomach) and mechanical abrasions (mouth)
III. Determines ABO blood types
What were the 3 movements of the membrane lipids?
I. Lateral Diffusion
II. Flexion
III. Flip Flop
Why are Flip Flops needed?
Lipids are only added to the cytoplasmic leaflet and flip flops are needed to get the lipids exoplasmic leaflet
What influences membrane fluidity? (3)
I. Temperature
II. Saturated vs Unsaturated
III. Cholesterol (animals)
How does temperature affect fluidity?
Higher temp - increased fluidity
How does saturated vs unsaturated fatty acid tails affect fluidity?
More saturated - decreased fluidity
How does cholesterol affect the fluidity?
More cholesterol - decreased fluidity
How does the membrane stay fluid at low temperatures? (4)
I. Desaturation
II. Reshuffling
III. Alter phospholipid synthesis
IV. Increased cholesterol content (animals)
How does desaturation help fluidity?
Creates double bonds to increase fluidity
How does reshuffling help fluidity?
Reshuffling the fatty acid tails so the bent tails are on the same polar head
How does altering the phospholipid synthesis help fluidity?
Favors synthesis of unsaturated phospholipids
How does the cholesterol help fluidity?
Increase cholesterol content seen in hibernating animals
Two forms of bulk transport
I. Endocytosis
II. Exocytosis
What's the general mechanism of endocytosis?
Involves invagination of the plasma membrane which removes a portion of the membrane
What are the three forms of endocytosis?
I. Phagocytosis
II. Pinocytosis
III.Receptor mediated endocytosis
What does Pinocytosis do?
Ingests liquids and dissolved substances
What does Phagocytosis do?
Ingests large matter
What does receptor mediated endocytosis do?
Ingests specific substances by target molecules attaching to receptors an the pit folding in on itself
Define exocytosis
Excretion of substances
What's the general mechanism of exocytosis?
secretory vesicles merge with membrane and release materials out of the cell
How does selective transport occur? (2)
I. Directly through membrane
II. Through transport proteins
What molecules can pass directly through the membrane?
-Very small
-Small uncharged and polar molecules
What molecules can't pass through the membrane?
-Very large
-Ions
Two types of membrane transport proteins
I. Channel protein
II. Carrier protein
What are the properties of membrane transport proteins? (3)
I. Selective
II. Mostly Ion Channels
III. Gates regulate amount
What's the general mechanism of carrier proteins?
Changes shape to allow molecules through
What are three types of carrier proteins?
I. Uniport
II. Symport
III. Antiport
Define Uniport
Transports one substance in one direction
Define symport
2 substances in one direction
Define antiport
2 substances in opposite directions
What group is symport and antiport a part of?
Coupled transport
Define ATP
energy source
Define ATPase
enzyme that hydrolyzes ATP which releases energy
What are the steps for Na+/K+ ATPase?
1. 3 Na+ bind
2. ATP binds
3. ATP hydrolysis
4. Shape change and release of Na+
5. Potassium binds
6. Dephosphorylation
7. Release 2 K+
What are the 3 important things of ATPase cycle?
I. Establishes Na+ gradient to drive active transport
II. Establishes membrane potential
III. Raises ion concentration and causes water to leave the cell
Define osmosis
diffusion of water across a selective membrane
2 ways water diffuses through a membrane
I. Directly through (limited)
II. Channel proteins (aquaporins)
3 ways animal cells are affected by osmosis
I. Hypertonic (shrivel cell)
II. Isotonic (normal cell)
III. Hypotonic (burst cell)
Why don't Hypotonic enviroments affect plants?
Cell wall prevents excessive uptake of water
How does a hypertonic enviroment affect plants?
Causes central vacuole to pull away from the cell wall
Define osmoregulation
control of water balance
3 ways to counter excessive water uptake
I. Live in isotonic environment
II. Bathe cell in isotonic fluid (blood)
III. Special adaptions
What are 3 special adaptions?
I. Less permeable plasma membrane
II. Contractile vacuole that stores water and discharges it outside the cell when full