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124 Cards in this Set

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category of compounds containing carbon, hydrogen, and oxygen that are hydrophobic

lipids

4 functions of lipids

- energy storage


- insulation


- protein transporter in blood (lipoproteins)


- cell membranes

3 types of lipids

- triglycerides*


- phospholipids*


- sterols




* = basic unit is fatty acids

structure of fatty acids

chain of C and H, with a carboxylic acid (-COOH) at one end

fatty acids can vary by __________.

- length of chain


- whether C has any double bonds


- the # of C=C double bonds

2 categories of lipids

- saturated: all C-C, solid at room temp.


- unsaturated: 1 or more C=C, more liquid at room temp.

2 types of unsaturated fatty acids

- monounsaturated: one C=C


- polyunsaturated: > one C=C

glycerol backbone + 3 fatty acids = ?

triglycerides




*most common lipid


*referred to as fats

glycerol backbone + 2 fatty acids + phosphate = ?

phospholipids




*phosphate containing head is hydrophilic



an emulsifier (part of bile) found in food (eggs) or added (dressing)

lecithin

phospholipid + protein = ?

lipoprotein

- sterol


- important role in cell membrane structure


- precursor of important compounds in body


- hormone precursor


- not required in diet

cholesterol

enzyme that breaks down fats

lipase

fatty acid absorption:




small chain fatty acids + lecithin = micelles ->




longer chain fatty acids ->

small chain fatty acids + lecithin = micelles -> go to blood




longer chain fatty acids -> go to lymphatic system via chylomicrons

transport fat through lymphatic system and blood

lipoproteins (chylomicrons)

delivers fat from liver to cells then converts it into LDL

very low-density lipoprotein (VLDL)

"bad" lipoprotein:




"good" lipoprotein:

"bad": low-density lipoprotein (LDL), deposits cholesterol in artery walls


"good": high-density lipoprotein (HDL), removes chol. from body

2 types of essential fatty acids

- linoleic acid (omega-6)


- alpha-linoleic acid (omega-3)




*keep membranes healthy


*make eicosanoids

proportion of protein that comes from animal sources

2/3

the predominant structural and functional materials in every cell

proteins

proteins contain what four elements?

C, H, O, and N

the building blocks of proteins

amino acids

structure of amino acids

carbon with an attached H, amine group (-NH2), carboxylic acid (-COOH), and side chain (unique)

number of unique amino acids

20

amino acids are linked together by __________.

peptide bonds

interactions of the unique side chains in amino acids cause the protein to __________.

fold into its 3D shape

a protein's shape determines its __________.

function

change in protein shape can cause problems such as __________.

sickle-cell anemia

number of amino acids that are essential

9

a protein becoming unfolded and changing shape, but not changing the amino acid sequence

denaturing

causes of protein denaturing

- heat (cooking)


- acids/bases


- beating, mixing, mech. digestion


- salts (marinades)

proteins are digested and absorbed in the __________ and __________.

stomach and small intestine

breaks down proteins into polypeptides in the stomach

pepsin

small intestine breaks down polypeptides into these 3 things

tripeptides, dipeptides, and individual amino acids

amino acids enter blood and travel to __________ via the __________.

liver via the hepatic portal vein




*used to make new proteins or as an energy source

protein synthesis starts with __________.

DNA

occurs inside the nucleus and writes the code (mRNA) to create proteins

transcription

occurs inside the cytoplasm and is performed by ribosomes to translate the code for protein synthesis

translation

brings the amino acids to the ribosomes for building

tRNA

DNA segment that codes for protein

gene

proteins are used for these 4 things

- structural and mechanical support


- build most enzymes, hormones, and antibodies


- maintain fluid balance


- maintain acid/base balance

fibrous protein that is most abundant

collagen

most abundant tissue type that is made up of mostly collagen

connective tissue (bones, tendons, ligaments)

dietary proteins ---digestion---> __________


---protein synthesis---> body proteins

amino acid pool

1. eat proteins, break down to amino acids, absorb


2. amino acids go to amino acid pool

protein turnover

protein degraded = protein synthesized

protein balance

amino acids can be broken down and have their amine group removed, this amine group is converted into __________.

urea (urine)

protein requirements per day

multiply weight in kg by 0.8g of protein (divide lbs by 2.2kg)

easily digestible proteins that contain all of the essential amino acids

quality proteins

proteins that contain all of the essential amino acids

complete proteins (animal sources)

proteins that do not have all of the essential amino acids

incomplete proteins (plant sources, with exception of soy and quinoa)

proteins that can be combined to form a complete protein

complimentary proteins

deficiency in protein can cause __________ and __________.

kwashiorkor and marasmus (overall calorie deficiency)

organic, essential micronutrients

vitamins

2 categories of vitamins

- fat-soluble


- water-soluble

the 4 fat-soluble vitamins

vitamins A, D, E, and K

type of vitamins that can be stored in the body

fat-soluble

type of vitamins that are not stored in the body

water-soluble (excesses can still be harmful)

2 types of water-soluble vitamins

vitamin Bs and C

how a vitamin is absorbed from food

bioavailibilty

vitamins can be destroyed with what 3 things?

air, water, or heat

retinoids are what vitamin?

vitamin A

most-usable form of retinoids in the body

retinol

pre-formed vitamin A is only found in __________.

animal foods

provitamin A that some plants contain

carotenoids (such as beta-carotene in carrots)

4 functions of vitamin A

- healthy eyes and skin


- cell differentiation


- bone health


- immunity

carotenoids are not toxic, but can cause __________.

carotenodermia (orange skin)

a chronic deficiency of vitamin A causes __________, and eventually __________.

nightblindness, and eventually xerophthalmia (#1 cause of blindness in children in developing countries)

alpha-tocopherol is the most active form of this vitamin

vitamin E (tocopheryl is the synthetic version)

the function of vitamin E

powerful antioxidant that protects cell membranes from free radicals (free radicals can cause macular degeneration)

vitamins C and E, the mineral selenium, and the phytochemicals carotenoids and flavenoids are all __________.

antioxidants

menaquinone and phylloquinone are both this type of vitamin

vitamin K

2 functions of vitamin K

- blood clotting


- bone health

this vitamin is called the sunshine vitamin

vitamin D

__________ in skin is converted to the inactive form of vitamin D

cholesterol

the inactive form of vitamin D is converted into the circulating form in the __________ and to the active form in the __________.

liver and kidneys

2 functions of vitamin D

- active form acts as a hormone


- regulates calcium and phosphorus in bones

an excess of vitamin D can cause __________.

hypercalcemia (calcium deposits in kidneys, lungs, and blood vessels)

a deficiency of vitamin D can cause __________.

rickets in children and osteomalacia in adults

the first B vitamin discovered, thiamin, is which B vitamin?

B1

3 functions of vitamin B1 thiamin

- nerve impulse


- metabolism


- breaks down alcohol

a deficiency of vitamin B1 thiamin can cause __________.

beriberi (loss of appetite, weight, memory, and confusion)

light-sensitive B vitamin, riboflavin

B2

function of vitamin B2 riboflavin

energy metabolism

an excess of vitamin B2 riboflavin can cause __________.

bright yellow urine (not toxic)

niacin is which B vitamin?

B3

3 functions of vitamin B3 niacin

- energy metabolism


- synthesize fat and cholesterol


- healthy skin and digestive system

B3 vitamin niacin can be made in the body from __________.

tryptophan

an excess of B3 vitamin niacin can cause __________.

toxicity to liver

a deficiency of B3 vitamin niacin can cause __________.

pellagra (four D's): dermatitis, diarrhea, dementia, death

pyridoxine and related compounds are which B vitamin?

B6

4 functions of vitamin B6 pyridoxine

- coenzyme


- make amino acids, converts tryptophan into B3


- immune and nervous system health


- metabolize fats and carbs

an excess of vitamin B6 pyridoxine can cause __________.

nerve damage

a deficiency of vitamin B6 pyridoxine can cause ___________.

sore tongue, depression, and confusion

folate is which type of B vitamin?

B9 (synthetic form is folic acid)

function of B9 vitamin folate

DNA synthesis

deficiency of vitamin B9 folate can cause __________.

deformations during pregnancy, macrocytic anemia

B vitamin that contains cobalt

B12

3 functions of B12 vitamin

- make DNA


- use certain fatty acids and amino acids


- healthy nerves and cells

vitamin B12 requires this to be absorbed

intrinsic factor

a deficiency in B12 vitamin can cause __________.

macrocytic anemia

ascorbic acid is what vitamin?

vitamin C

7 functions of vitamin C

- coenzyme


- makes collagen


- healthy bones, skin, blood vessels, and teeth


- immune system


- antioxidant


- helps absorb iron


- breaks down histamine

a deficiency in vitamin C can cause __________.

scurvy

pantothenic acid (B5) and biotin function as __________.

a coenzyme

lubricant for joints, eyes, and saliva, and protective cushion for brain, organs, and a fetus

water

minerals that help maintain fluid balance

electrolytes (Na, K, and Cl)

dehydration can cause the concentration of this electrolyte to increase in the blood

Na (decreased volume of blood)

the thirst mechanism triggers the secretion of this to reduce urine production

anti-diuretic hormone (ADH)

too much water intake can cause __________.

hyponatremia (water intoxication)

how much water do you need daily?

approximately 1/2 your body weight

minerals that you need >100 micrograms per day

major minerals (macrominerals)

minerals that you need <20 micrograms per day

trace minerals (microminerals)

the 4 trace minerals

Fe, Zn, Cu, and I

__________ increases the risk of hypertension

Na

most abundant mineral

Ca

not enough Ca mineral will cause __________.

the release of Ca from bones

2nd most abundant mineral

P

P mineral deficiency can cause __________.

osteoperosis (low bone density is osteopenia, very low is osteoperosis)

Mg mineral functions

- coenzyme


- synthesizes protein

2 types of Fe mineral

heme and non-heme Fe

functions of Zn mineral

- coenzyme


- DNA synthesis, growth, and immune system

function of F mineral

protects teeth

I mineral is needed by the __________.

thyroid