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124 Cards in this Set
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category of compounds containing carbon, hydrogen, and oxygen that are hydrophobic |
lipids |
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4 functions of lipids |
- energy storage - insulation - protein transporter in blood (lipoproteins) - cell membranes |
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3 types of lipids |
- triglycerides* - phospholipids* - sterols * = basic unit is fatty acids |
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structure of fatty acids |
chain of C and H, with a carboxylic acid (-COOH) at one end |
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fatty acids can vary by __________. |
- length of chain - whether C has any double bonds - the # of C=C double bonds |
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2 categories of lipids |
- saturated: all C-C, solid at room temp. - unsaturated: 1 or more C=C, more liquid at room temp. |
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2 types of unsaturated fatty acids |
- monounsaturated: one C=C - polyunsaturated: > one C=C |
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glycerol backbone + 3 fatty acids = ? |
triglycerides *most common lipid *referred to as fats |
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glycerol backbone + 2 fatty acids + phosphate = ? |
phospholipids *phosphate containing head is hydrophilic |
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an emulsifier (part of bile) found in food (eggs) or added (dressing) |
lecithin |
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phospholipid + protein = ? |
lipoprotein |
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- sterol - important role in cell membrane structure - precursor of important compounds in body - hormone precursor - not required in diet |
cholesterol |
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enzyme that breaks down fats |
lipase |
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fatty acid absorption: small chain fatty acids + lecithin = micelles -> longer chain fatty acids -> |
small chain fatty acids + lecithin = micelles -> go to blood longer chain fatty acids -> go to lymphatic system via chylomicrons |
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transport fat through lymphatic system and blood |
lipoproteins (chylomicrons) |
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delivers fat from liver to cells then converts it into LDL |
very low-density lipoprotein (VLDL) |
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"bad" lipoprotein: "good" lipoprotein: |
"bad": low-density lipoprotein (LDL), deposits cholesterol in artery walls "good": high-density lipoprotein (HDL), removes chol. from body |
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2 types of essential fatty acids |
- linoleic acid (omega-6) - alpha-linoleic acid (omega-3) *keep membranes healthy *make eicosanoids |
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proportion of protein that comes from animal sources |
2/3 |
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the predominant structural and functional materials in every cell |
proteins |
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proteins contain what four elements? |
C, H, O, and N |
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the building blocks of proteins |
amino acids |
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structure of amino acids |
carbon with an attached H, amine group (-NH2), carboxylic acid (-COOH), and side chain (unique) |
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number of unique amino acids |
20 |
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amino acids are linked together by __________. |
peptide bonds |
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interactions of the unique side chains in amino acids cause the protein to __________. |
fold into its 3D shape |
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a protein's shape determines its __________. |
function |
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change in protein shape can cause problems such as __________. |
sickle-cell anemia |
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number of amino acids that are essential |
9 |
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a protein becoming unfolded and changing shape, but not changing the amino acid sequence |
denaturing |
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causes of protein denaturing |
- heat (cooking) - acids/bases - beating, mixing, mech. digestion - salts (marinades) |
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proteins are digested and absorbed in the __________ and __________. |
stomach and small intestine |
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breaks down proteins into polypeptides in the stomach |
pepsin |
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small intestine breaks down polypeptides into these 3 things |
tripeptides, dipeptides, and individual amino acids |
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amino acids enter blood and travel to __________ via the __________. |
liver via the hepatic portal vein *used to make new proteins or as an energy source |
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protein synthesis starts with __________. |
DNA |
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occurs inside the nucleus and writes the code (mRNA) to create proteins |
transcription |
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occurs inside the cytoplasm and is performed by ribosomes to translate the code for protein synthesis |
translation |
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brings the amino acids to the ribosomes for building |
tRNA |
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DNA segment that codes for protein |
gene |
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proteins are used for these 4 things |
- structural and mechanical support - build most enzymes, hormones, and antibodies - maintain fluid balance - maintain acid/base balance |
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fibrous protein that is most abundant |
collagen |
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most abundant tissue type that is made up of mostly collagen |
connective tissue (bones, tendons, ligaments) |
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dietary proteins ---digestion---> __________ ---protein synthesis---> body proteins |
amino acid pool |
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1. eat proteins, break down to amino acids, absorb 2. amino acids go to amino acid pool |
protein turnover |
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protein degraded = protein synthesized |
protein balance |
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amino acids can be broken down and have their amine group removed, this amine group is converted into __________. |
urea (urine) |
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protein requirements per day |
multiply weight in kg by 0.8g of protein (divide lbs by 2.2kg) |
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easily digestible proteins that contain all of the essential amino acids |
quality proteins |
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proteins that contain all of the essential amino acids |
complete proteins (animal sources) |
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proteins that do not have all of the essential amino acids |
incomplete proteins (plant sources, with exception of soy and quinoa) |
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proteins that can be combined to form a complete protein |
complimentary proteins |
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deficiency in protein can cause __________ and __________. |
kwashiorkor and marasmus (overall calorie deficiency) |
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organic, essential micronutrients |
vitamins |
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2 categories of vitamins |
- fat-soluble - water-soluble |
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the 4 fat-soluble vitamins |
vitamins A, D, E, and K |
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type of vitamins that can be stored in the body |
fat-soluble |
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type of vitamins that are not stored in the body |
water-soluble (excesses can still be harmful) |
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2 types of water-soluble vitamins |
vitamin Bs and C |
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how a vitamin is absorbed from food |
bioavailibilty |
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vitamins can be destroyed with what 3 things? |
air, water, or heat |
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retinoids are what vitamin? |
vitamin A |
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most-usable form of retinoids in the body |
retinol |
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pre-formed vitamin A is only found in __________. |
animal foods |
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provitamin A that some plants contain |
carotenoids (such as beta-carotene in carrots) |
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4 functions of vitamin A |
- healthy eyes and skin - cell differentiation - bone health - immunity |
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carotenoids are not toxic, but can cause __________. |
carotenodermia (orange skin) |
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a chronic deficiency of vitamin A causes __________, and eventually __________. |
nightblindness, and eventually xerophthalmia (#1 cause of blindness in children in developing countries) |
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alpha-tocopherol is the most active form of this vitamin |
vitamin E (tocopheryl is the synthetic version) |
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the function of vitamin E |
powerful antioxidant that protects cell membranes from free radicals (free radicals can cause macular degeneration) |
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vitamins C and E, the mineral selenium, and the phytochemicals carotenoids and flavenoids are all __________. |
antioxidants |
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menaquinone and phylloquinone are both this type of vitamin |
vitamin K |
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2 functions of vitamin K |
- blood clotting - bone health |
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this vitamin is called the sunshine vitamin |
vitamin D |
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__________ in skin is converted to the inactive form of vitamin D |
cholesterol |
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the inactive form of vitamin D is converted into the circulating form in the __________ and to the active form in the __________. |
liver and kidneys |
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2 functions of vitamin D |
- active form acts as a hormone - regulates calcium and phosphorus in bones |
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an excess of vitamin D can cause __________. |
hypercalcemia (calcium deposits in kidneys, lungs, and blood vessels) |
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a deficiency of vitamin D can cause __________. |
rickets in children and osteomalacia in adults |
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the first B vitamin discovered, thiamin, is which B vitamin? |
B1 |
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3 functions of vitamin B1 thiamin |
- nerve impulse - metabolism - breaks down alcohol |
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a deficiency of vitamin B1 thiamin can cause __________. |
beriberi (loss of appetite, weight, memory, and confusion) |
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light-sensitive B vitamin, riboflavin |
B2 |
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function of vitamin B2 riboflavin |
energy metabolism |
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an excess of vitamin B2 riboflavin can cause __________. |
bright yellow urine (not toxic) |
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niacin is which B vitamin? |
B3 |
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3 functions of vitamin B3 niacin |
- energy metabolism - synthesize fat and cholesterol - healthy skin and digestive system |
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B3 vitamin niacin can be made in the body from __________. |
tryptophan |
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an excess of B3 vitamin niacin can cause __________. |
toxicity to liver |
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a deficiency of B3 vitamin niacin can cause __________. |
pellagra (four D's): dermatitis, diarrhea, dementia, death |
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pyridoxine and related compounds are which B vitamin? |
B6 |
|
4 functions of vitamin B6 pyridoxine |
- coenzyme - make amino acids, converts tryptophan into B3 - immune and nervous system health - metabolize fats and carbs |
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an excess of vitamin B6 pyridoxine can cause __________. |
nerve damage |
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a deficiency of vitamin B6 pyridoxine can cause ___________. |
sore tongue, depression, and confusion |
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folate is which type of B vitamin? |
B9 (synthetic form is folic acid) |
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function of B9 vitamin folate |
DNA synthesis |
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deficiency of vitamin B9 folate can cause __________. |
deformations during pregnancy, macrocytic anemia |
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B vitamin that contains cobalt |
B12 |
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3 functions of B12 vitamin |
- make DNA - use certain fatty acids and amino acids - healthy nerves and cells |
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vitamin B12 requires this to be absorbed |
intrinsic factor |
|
a deficiency in B12 vitamin can cause __________. |
macrocytic anemia |
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ascorbic acid is what vitamin? |
vitamin C |
|
7 functions of vitamin C |
- coenzyme - makes collagen - healthy bones, skin, blood vessels, and teeth - immune system - antioxidant - helps absorb iron - breaks down histamine |
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a deficiency in vitamin C can cause __________. |
scurvy |
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pantothenic acid (B5) and biotin function as __________. |
a coenzyme |
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lubricant for joints, eyes, and saliva, and protective cushion for brain, organs, and a fetus |
water |
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minerals that help maintain fluid balance |
electrolytes (Na, K, and Cl) |
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dehydration can cause the concentration of this electrolyte to increase in the blood |
Na (decreased volume of blood) |
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the thirst mechanism triggers the secretion of this to reduce urine production |
anti-diuretic hormone (ADH) |
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too much water intake can cause __________. |
hyponatremia (water intoxication) |
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how much water do you need daily? |
approximately 1/2 your body weight |
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minerals that you need >100 micrograms per day |
major minerals (macrominerals) |
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minerals that you need <20 micrograms per day |
trace minerals (microminerals) |
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the 4 trace minerals |
Fe, Zn, Cu, and I |
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__________ increases the risk of hypertension |
Na |
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most abundant mineral |
Ca |
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not enough Ca mineral will cause __________. |
the release of Ca from bones |
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2nd most abundant mineral |
P |
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P mineral deficiency can cause __________. |
osteoperosis (low bone density is osteopenia, very low is osteoperosis) |
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Mg mineral functions |
- coenzyme - synthesizes protein |
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2 types of Fe mineral |
heme and non-heme Fe |
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functions of Zn mineral |
- coenzyme - DNA synthesis, growth, and immune system |
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function of F mineral |
protects teeth |
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I mineral is needed by the __________. |
thyroid |