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109 Cards in this Set

  • Front
  • Back
What are the upper airways?
External nose, Nasal Cavity, Pharynx
What are the lower airways?
Larynx, trachea, bronchi, & lungs
What is the path of air from nose to alveolus?
air > external nose > nasal cavity > nasopharynx > larynx > trachea > Lft & Rt bronchi > secondary bronchi > tertiary bronchi > bronchioles > alveoli (site of gas exchange)
What is Surfactant pressure?
What is Surfactant pressure?
~ decreases surface tension of fluid in the alveoli

~reduces lungs from collapsing

~lacks in babies with hyaline membrane disease

~decreases energy required to keep the lungs inflated.
What is Pleural pressure?
~is the pressure surrounding the lung, within the pleural space.

~pleural pressure in the cavity is less than alveolar pressure, causing aveoli to expand.
describe the respiratory center of brain
~located in the medulla oblongata and lower pons.

1) sends signals to the diaphragm through phrenic nerve
2) has neurons that produce action potentials for a short time and then fatigue
3)sends signals to some respiratory muscles through spinal nerves
White blood cell types

Granulocytes
~contain large cytoplasmic granules
White blood cell types

Agranulocytes
~contain very small granules that cannot be seen easily with the microscope
Granulocyte

Neutrophils
~most common WBC with 2-4 lobes that stain light pink/reddish purple.

~phagocytize microorganisms and other substances
Granulocyte

Basophils
~least common WBC with 2 distinct lobes that stain blue-purple

~releases histamine (promotes inflammation)

~releases heparin (prevents clot formation)
Granulocyte

Eosophils
~contain bilobed nucleus
~granules stain bright red
~releases chemicals that reduce inflammation
~attacks certain parasites
Agranulocytes

Lymphocytes
~smallest WBC with round nucleus whose cytoplasm forms a ring around nucleus
~produces antibodies & other chemicals responsible for killing microorganisms
~contribute to allergic reactions, tumor control and immune system regulation
Agranulocytes

Monocytes
~ largest WBC with round, kidney-shaped or horseshoe shaped nucleus
~has more cytoplasm than lymphocyte
~phagocytic cell in blood
~leaved blood to become macrophage, which phagocytizes bacteria, dead cells, cell fragments, and other debris
Medulla Oblongata
~regulation of heart rate, breathing, swallowing, vomiting, coughing, sneezing, balance & coordination
Medulla Oblongata
~Sensory nerves conduct action potentials to the cardioregulatory & vasomotor centers during a baroreceptor reflex
Medulla Oblangata
~Chemoreceptors monitor CO2 & PH, detects how much CO2 is in the bloodstream.
~Sends impulses through the nerves to the diaphragm which makes us breathe faster and get rid of CO2
Sympathetic system
~responsible for fight for flight
~prepared body for physical activity
~secretes norepinephrine
Relationship of CO2 to PH
As CO2 increases, blood PH decreases & becomes more acidic, because CO2 reacts with H2O to form H2CO3. ^PH=v H+. To fix his, we must urine out H2CO3 to = H2CO3 v = ^H+
Relationship of pressure and volume
~during inspiration alveoli pressure is less than atmospheric pressure
~When the diaphragm contracts, thoracic cavity volume increases
~during quiet breathing, passive recoil of the lung and thoracic wall causes expiration
~during labored breathing, the internal intercostals and abdominal muscle assist in expiration
Functions and components of the respiratory system
~gas exchange, regulation of blood PH, voice production, innate immunity
~Pulmonary ventilation = breathing
~External respiration-air in the lungs, gas exchange; load CO2 & unload O2
~transport of respiratory gases
~internal respiration
~cellular respiration
Inspiratory Reserve Volume (IRV)
~Largest lung volume that can be inspired forcefully beyond resting tidal volume (abt 3000ML)
Vital Capacity (VC)
~VC=Inspiratory reserve volume (IVR) +Tidal Volume(VT)+expiratory reserve volume(ERV)
~maximum volume a person can expel from the respiratory tract after maximum inpiration
Tidal Volume (VT)
~Volume of air inspired or expired with each breath at rest
~quiet breathing results in a tidal volume of abt 500ML
Respiratory Acidosis
~results when the respiratory system is unable to eliminate enough amts of CO2
~CO2 accumulates in the circulatory system, causing PH of the body fluids to decline
Respiratory Alkalosis
~results from hyperventilation
~occurs when blood PH is above 7.4
condition for gas exchange to move between the alveoli and the pulmonary capillary
~gas exchange occurs in the alveolar ducts and alveoli where there is contact with the pulmonary capillary = respiratory membrane
How does CO2 transport in the blood occur?`
~most CO2 is transported as bicarbonate ions in the blood
Formed elements

Red blood cells
~Also named erythrocytes
~take up 95% volume
Formed elements

White Blood cells
~Also called leukocytes
~make - up remaining 5%
Formed elements

Platelets
~Also called thrombocytes
~makeup remaining 5%
ABO Blood typing
~type A = type b antibody
~type B = type A antibody
~type AB = no antibody (known as the universal recipient)
~type O = type A and type B antibodies (known as the universal donor)
Right side of heart
~consists of rt atrium, rt ventricle, & pulmonary trunk
~carried deoxygenated blood
~forces blood to flow to the lungs
Left side of heart
~consists of lft atrium, lft ventricle, aorta, pulmonary veins.
~carries oxygenated blood to the body
Pulmonary veins
~consists of 4 veins
~2 from lft lung, 2 from rt lung
~They carry oxygenated blood from lungs & deposits this blood into the left atrium
Coronary Arteries
~there are 2 arteries that originate from the base of the aorta that supply oxygenated blood to the wall of the hrt
Coronary sinuses
~large vein located within the coronary sulcus
~collects deoxygenated blood from the heart muscle by way of the coronary veins & drains into the rt atrium
Pulmonary trunk
~receives deoxygenated blood pumped through the pulmonary semilunar valves
~divides to form rt & lft arteries that carry deoxygenated blood to the rt lungs where the blood gas exchange happens
Superior Vena Cava
returns deoxygenated blood from the head, neck, thorax, & upper limbs to the rt atrium
Inferior Vena Cava
~returns deoxygenated blood from the abdomen, pelvis, & lower limbs to the rt atrium
Tricuspid valve
~has 3 cusps
~located between rt atrium and rt ventricle
Bicuspid (mitral) valve
~has 2 cusps
~located between the the lft arium and lft ventricle
Aortic Semilunar valve
~prevents backflow from the aorta back toward the lft ventricle
pulmonary Semilunar valve
prevents backflow from the pulmonary trunk back toward the rt ventricle.
Interventricular septum
~partition that separates the rt & lft atria
Normal pathway of blood flow
1)superior/inferior vena cava drain deoxygenated blood into rt atrium
2)blood flows through tricuspid valve into rt ventricle. Atria contracts & ejects remaining blood into ventricle
3) rt ventricle contracts & ejects blood through pulmonary trunk
4)deoxygenated blood travels through pulmonary trunk & goes through lft & rt arteries. Goes to lungs for gas exchange
5)Oxygenated blood is carried out of lungs by pulmonary veins & drains into lft atrium
6)lft atrium pushes blood through bicuspid valve into lft ventricle
7)lft ventricle contracts & oxygenated blood is pumped through the aortic semilunar valve, & out of aorta, sending oxygenated blood back into circulation
SA Node
~functions as the hearts pacemaker
~located in the superior wall of the rt atrium
~initiates heart contraction
~produce action potential that spread over the rt & Lft atrium, causing them to contract
AV Node
~located in the lower portion of the rt atrium in the interatrial septum
~serves as a delay signal to allow the atria to complete contraction before action potentials are delivered to the ventricles
Atrial ventricular bundle (Bundle of His)
~Only electrical connection between the atria & ventricles.

~located in the superior inter-ventricular septum
Bundle Branches
~divides into left & right bundle branches

~leads down towards the apex of the hrt
Purkinje fibers
~conduction myofibers located within the papillary muscles of the ventricles.

~conduct impulses into mass of ventricular muscle tissue, which causes ventricles to contract & forces blood out of lower chamber
pwave
~small upward wave that represents atrial depolarization

~beginning of pwave precedes the onset of atrial contraction
QRS
~represents onset ventricular depolarization

~beginning of QRS complex precedes ventricular contraction
T-wave
~dome shaped upward reflection

~represents ventricular repolarization
~occurs right before ventricles relax
Tachychardia
~occurs when heart rate is more than 100beats per minute
Bradychardia
~occurs when hear rate is less than 60 beats/min
Pulmonary Arteries
~2 vessels that branch off from the pulmonary trunk: left & rt pulmonary artery
~each extend into lungs where deoxygenated blood undergoes blood exchange
pulmonary capillaries
~smallest, thinnest blood vessels in the lungs that permit the exchange of gases, nutrients & wastes between blood and tissues
systemic vessels
~transport blood through all parts of body from lft ventricle to rt atrium
~supply oxygen & nutrients to all cells of the body
~are part of of the peripheral circulation
~carry away CO2 & waste from all cells of the body
all involved in respiration
~gas exchange between blood & tissue = internal , ventilation, movement of air in & out of lungs, gas exchange b/w air in lungs & blood = external respiration
pulmonary veins
~there are 4 pulmonary veins (2 frm each lung) that exit the lungs & carry deoxygenated blood to lft atrium, which pumps blood through bicuspid valve into lft ventricle, then through the aortic semilunar valve into the aorta to be circulated to the body
hemoglobin recycling in the spleen
old, abnormal or damaged rbc's are removed from blood by macrophages found the spleen or liver. .macrophages the globin part of the hemoglobin molecules is broken down into amino acid that is reused to produce other proteins. The iron released from the heme part of the hemoglobin molecule is transported in the blood to the red bone marrow and reused to produce new hemoglobin.
~the heme molecules are converted to bilirubin that is normally taken up by the liver & released into the small intestine as part of bile.
correct sequence of the pharynx
~nasopharynx
~oropharynx
~laryngopharynx
Respiratory passages largest to smallest
1)bronchi
2)bronchioles
3)terminal bronchioles
4)respiratory bronchioles
5)alveoli
Respiratory membrane
~membrane in the lungs across in which gas exchange occurs with blood
~consists of a thin layer of fluid, alveolar epithelium, basement membrane of the alveolar epithelium, interstitial space, basement membrane of capillary endothelium, & capillary endothelium
pleural cavity
~lie between the visceral and parietal
~parietal pleura are filled with pleural fluid
pressure during inspiration
~As the external intercostals & diaphragm contract, the lungs expand. The expansion of the lungs causes the pressure in the lungs (and alveoli) to become slightly negative relative to atmospheric pressure. As a result, air moves from an area of higher pressure (the air) to an area of lower pressure (our lungs & alveoli).
pressure during expiration
~the respiration muscles relax & lung volume descreases. This causes pressure in the lungs (and alveoli) to become slight positive relative to atmospheric pressure. As a result, air leaves the lungs.
relation b/w the diaphragm and thoracic cavity
~When the diaphragm contracts, thoracic cavity volume increases the pressure in the thoracic cavity decreases
~the air pressure inside the thoracic cavity is less than the atmospheric pressure & air rushes into lungs to equalize pressure greadient
quiet breathing and passive recoil
~during quiet breathing , passive recoil of the lung & thoracic wall cause expiration
labored breathing
~during labored, the internal intercostals & abdominal muscle assist in expiration
oxygen transport
~O2 combines with the heme group of the hemoglobin to form oxyhemoglobin
~an increase in temperature increases the amt of O2 released in the tissue capillaries
gas exchange across respiratory membrane
~thickness of the membrane
~total surface area of membrane, if reduced there is a reduced rate of diffusion across the membrane
~rate at which gas diffuses through the fluids
~the concentration gradient for gases across the membrane
pulmonary circulation
~system of blood vessels that carries blood from rt ventricle to to the lungs, and back to lft atrium
~brings deoxygenated blood from the systemic circulation back to the heart to be oxygenated in lungs
systematic circulation
~carry blood back from lft ventricle to tissues th blood troughout the body.
~oxygenated blood from pulmonary veins pass from lect atrium onto lft ventricle, and from left ventricle into the aorta
~arteries distribute blood from the aorta throughout the rest of the body's circulation
hemoglobin
~main component of the RBC's
~heme gives it its red pigment and contains iron atom necessary for oxygen transport
~iron binds to O2 molecule, which is picked up in lungs and released to other tissues
~hemoglobin that is bound to an O2 molecule is bright red
~hemoglobin with no O2 molecule is darker red
pacemaker of heart
~the sa is the pacemaker of hrt located in the superior wall of the rt atrium & initiates the hear to contract
~produces action potential that spreads over rt & lft atria which produces contraction
~SA node has a larger # of CA2+ channels than other heart cells
~along with na+ channels, the ca2+ channels open spontaneously open & close at a rhythmic rate
primary bronchus
~one of the two main air passages that branch from the trachea and convey air to the lungs as part of the respiratory system. The right primary bronchus enters the right lung nearly opposite the fifth thoracic vertebra. The left primary bronchus divides into bronchi for the superior and anterior lobes of the lung.
secondary bronchus
~Secondary bronchi (also known as lobar bronchi) arise from the primary bronchi, with each one serving as the airway to a specific lobe of the lung.
respiratory bronchiole
~the smallest bronchioles (0.5 mm in diameter) that connect the terminal bronchioles to alveolar ducts; alveoli rise from part of the wall, thus permitting the exchange of gases.
terminal bronchiole
~the smallest bronchioles (0.5 mm in diameter) that connect the terminal bronchioles to alveolar ducts; alveoli rise from part of the wall, thus permitting the exchange of gases.
Sensory neuron
~responsible for converting various external stimuli that come from the environment into corresponding internal stimuli
sensory receptor
~responsible for converting various external stimuli that come from the environment into corresponding internal stimuli
motor neuron
~A neuron that conveys impulses from the central nervous system to a muscle, gland, or other effector tissue.
Effector organ
~A neuron that conveys impulses from the central nervous system to a muscle, gland, or other effector tissue.
vagus
~sensory to pharynx, larynx, and viscera
~motor to palate, pharynx, and larynx
~parasympathetic to viscera of thorax and abdomen
total lung capacity
~inspiratory=reserve volume+expiratory reserve volume+tidal volume+residual volume
tidal volume
~volume of air inspired or expired w/each breath.
~at rest, quiet breathing results in a tidal volume of abt 500ML
expiratory reserve volume
~amt of air that can be expired forcefully beyond the resting tidal volume
inspiratory capacity
~amt of air that can be inspired forcefully beyond the resting tidal volume
residual volume
~volume of air still remaining in the respiratory passages & lungs after maximum expiration
active transport
~ movement of all types of molecules across a cell membrane against its concentration gradient (from low to high concentration). In all cells, this is usually concerned with accumulating high concentrations of molecules that the cell needs, such as ions, glucose and amino acids.
endocardium
~smooth inner surface of the heart chambers consisting of simple squamous epithelium over a layer of connective tissue
~allows blood to easily move through the heart
epicardium
~visceral pericardium
~thin, serous membrane forming the smooth outer surface of the heart
myocardium
~thick middle layer of the heart
~composed of cardiac muscle cells
~responsible for contraction of muscle heart chambers
HDN
~stands for hemolytic ditsease of the newborn
~caused by rh incompatibility between an Rh-negative mother and an rh-positive fetus
~can be prevented by injecting rhogam
type 1cells
~form a simple squamous lining of the alveolar wall
type 2 cells
~interrupt above lining and secrete surfactant
heart sounds
Lubb
~the first heart sound
~lower pitch than the second sound
~occurs at the beginning of the ventricular systole
~results from closure of the AV valves
heart sounds
Dupp
~the second heart sound
~occurs at the beginning of ventricular diastole
~results from closure of the semilunar valves
internodal atrial muscle
~INTERNODAL ATRIAL MUSCLE FIBERS CONDUCT IMPULSES TO DISTANT REGIONS OF ATRIA
regulation of acid base balance
blood ph increases
~H+ secretes into urine and decreases hco3
~must release H+ to increase HCO3 (in kidneys you urine it out, in lungs you hypoventilate)
kidneys
~produce urine, which is conducted by the ureters to the bladder
~excrete nitrogenous wastes including urea, uric acid, and creatinine
~maintain normal water-salt balance &acid base balance of blood
~divided into renal cortex, renal medulla, & renal pelvis
nephrons
~functional unit of the kidneys
~each has its own blood supply
~afferent arteriole approaches the glomerular capsule &divides to become glomerulus, a capillary tuft
~the efferent arteriole leaves the capsule & branches into the peritubular capillary network
nephrons
~each region of the nephron is anatomically suited to its task in urine formation
~spaces between the podocytes of the glomerular capsule allow small molecules to enter the capsule from the glomerulus
urine formation steps
1) glomerular filtration
2)tubular reabsorption
3)tubular secretion
filtration
~filtering materials from glomariolous into bowmans capsule
tubular reabsorption
~reabsorption of solutes from the glomerular filtrate by the tubules, the conservation of protein, glucose and bicarbonate, and the conservation of the water that accompanies them.
~going from the tubule back to the peritubular capillaries
tubular secretion
~everything secreted & not reabsorbed will be peed out
~solutes are secreted across the wall of the nephron into the filtrate
regulation of acid base balance
blood ph increases
~HCO3 secretes into urine and decreases H+
~must release HCO3 to increase H+ (in kidneys you urine it out, in lungs you hyperventilate)