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10 Cards in this Set
- Front
- Back
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2 types of immune response:
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humoral, cell mediated
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What happens in humoral response?
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cloning of B-cells that result in production of antibodies
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What happens when papain is used?
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2 Fab and 1 Fc fragments
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what happens in cell-mediated response?
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cytotoxic T lymphocytes kill cells that display
foreign peptide fragments on their surface involves MHCs |
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What is MHC I?
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presents antigen to cytotoxic t-cells, can bind like a little bit of sequence
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What about MHC II?
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presents the antigen to helper-t cells
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what do t-cell receptors recognize?
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both the antigen and the MHC
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Structure of Hb?
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4 subunits (2a+2b), hydrophobic center
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What happens to the heme in T and R?
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In T it protrudes onto the His F8, in R it is more planar, and pulls His F8 towards porphyrin ring
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What happens to the iron when it is bound?
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oxidized to +3
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