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24 Cards in this Set

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Bipolar 1

manic and depressive episodes , mixed

Bipolar 2

Hypomanic, depressive. No FULL ON MANIA

Mania: expansive vs irritable


need to see this for 1 week

Expansive: not normal behavior. They think all is right with the world. sex with stangers




- irritable form is irritable

For acute mania(bi polar1) there needs to be impairment of function:

stop going to work, drains bank account. EMPIRE




Buying sprees in Manic phase / poor judgement in business ventures

need at least 4 symptoms




microwave story

grandiosity / decreased need for sleep/pressured speech/ flights of speech/ involvment / easily distracted/ self importance



Some patients with acute mania may have?




anti deprressant to bipolar when in depressive phase will do what?

psychotic symptoms like hallucinations. some drs treat for schizo.




YOUll make them fluctuate outta depression into MANIa

HYPOmania

less severe form of mani. no dellusion / hallucinations

mixed features

manic and hypomanic at the same time

dont know why ppl have bipolar disorder

DONT KNOW but 90% of time its relative linked. genetic

presenting symptoms of mania diagnostic :

difficult dont want to confuse with schizo(manic) or depression.




some drugs trigger bipolar pt into manic phase

Life ling disorder: put pt into remission means put them into stable normal mood




what kind of treatment

mainstay treatment are mood stabalizers!




Lithium is the newest drugs. we use anticonvulsents valproic acid




anti psychotics are used

mood stabilizer is deceiving

cant use them interchnagebly. some drugs favor manic side some favor depressive side.




some drugs for manitance some for acute

Valproate (valproic acid) and Depakote used for

acute and Maintenance

Lithium used for

MANIA and is acute and maintenance

Lamotrigene or lamictal

Bipolar 1 MAINTENANCE ONLY! be aware of rash

Combo tretament : Symbyax

olanzapine + Fluoxetine approved for maintenance

Quetipapine and Lurasidone

mania and mixed actute and maintenance

Adjunctivly use

anti depressants

Lithium

GOLD STANDARD FOR TREATING BI POLAR DISORDER




NArrow theraputic window. ppl toxic from lithium ppl die from it. KNOW SIDE EFFECT PROFILE.



VALPROIC ACID

SILVER star therapy - VERY GOOD shows better efficacy in ppl who have mixed states )depression and manai same time)




-irritable /dysphorric mania




- rapid cycle




valproic acid works better!





lithium has a long half life

even with good renals ppl can be toxic with lithium

treat D Insipidius with

Diuretic loop and thiazide

toxic on lithium levels greater than


reversible ?




related to high level concentrations were and For HOW LONG will tell you what?




so you do what to see?

greater than 2


NON REVERSIBLE !




how severe and toxic it will be




take a level !!

if pt is on nsaid / indomethacin /ibu these drugs can increase or decrease lithium ?




also diuretic/ ace inhibitos salt restriced diet SALT in general increases levels




caffine theophyline : DECREASE levels

It can INCREASE lithium




so decrease lithium dose since these increase levels