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16 Cards in this Set
- Front
- Back
- 3rd side (hint)
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CPE (enterotoxin)--pore forming toxin; toxins A-E, lecithinase, spores
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Clostridium perfringens
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cellulitis, fasciitis, micronecrosis (gas gangrene), transmission is usually trauma to skin; also beef, poultry, gravies, dried or pre-cooked foods are common modes of transmission
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botulism toxin A-G; an AB toxin that cleaves T snares and V snares associated with acetylcholine vesicles
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Clostridium botulinim
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can lead to flaccid paralysis, blurred vision, trouble speaking, limp baby (due to honey), often spreads through canned foods, antitoxin available, toxin used as BOTOX; also has wound and inhalation forms
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AB toxin that cleaves V-snares and T-snares associated with GABA vesicles (and glycine)
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Clostridium tetani
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spread through puncture wounds, get tetanus shot, causes muscle spasms that can be generalized or localized, also a neonatal form; treatment includes using immunoglobulins
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toxin A (CDT A) disrupts tight junctions and recruits neutrophils, toxin B (CDT B) disrupts tight junctions and causes actin depolymerization
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Clostridium difficile
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associated with post-antibiotic therapy resulting in pseudomembranous colitis; bloody diarrhea
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not given
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Lactobacillus
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normal vaginal flora
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not given
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Actinomyces
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causes granulomatous lesions and absecess in cervofacial, thoracic, abdominal, pelvic, and CNS regions; pus has sulfur granules (PMNs surrounded by bacterial filaments); molar tooth like colonies
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capsule, catalase, superoxide dismutase
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Bacteroids (fragilis)
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most common clinically isolated anaerobe; causes intraabdominal infections, genital tract infections, brain, skin, and soft tissue infections, and bacteremia
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opportunistic
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Fusobacterum
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leads to trench mouth or Vincent's angina
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cellulitis, fasciitis, micronecrosis (gas gangrene), transmission is usually trauma to skin; also beef, poultry, gravies, dried or pre-cooked foods are common modes of transmission
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Clostridium perfringens
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G+ large, spore-forming bacilli, double zone of β_hemolysin, lecithinase production, toxin analysis
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can lead to flaccid paralysis, blurred vision, trouble speaking, limp baby (due to honey), often spreads through canned foods, antitoxin available, toxin used as BOTOX; also has wound and inhalation forms
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Clostridium botulinim
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G+ large spore forming bacilli, ID toxin, anaerobe
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spread through puncture wounds, get tetanus shot, causes muscle spasms that can be generalized or localized, also a neonatal form; treatment includes using immunoglobulins
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Clostridium tetani
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G+ large spore forming bacilli, ID toxin, anaerobe
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associated with post-antibiotic therapy resulting in pseudomembranous colitis; bloody diarrhea
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Clostridium difficile
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G+ large spore, anaerobe, forming bacilli, ID toxin using ELISA
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normal vaginal flora
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Lactobacillus
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G+ bacilli, anaerobe
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causes granulomatous lesions and absecess in cervofacial, thoracic, abdominal, pelvic, and CNS regions; pus has sulfur granules (PMNs surrounded by bacterial filaments); molar tooth like colonies
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Actinomyces
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G+ branching bacilli, anaerobe
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most common clinically isolated anaerobe; causes intraabdominal infections, genital tract infections, brain, skin, and soft tissue infections, and bacteremia
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Bacteroids (fragilis)
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G- bacilli, anaerobe, CAT+, black colonies on BBE ( __ bile esculine agar), check resistance to kanamycin, colistin, and vancomycin
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leads to trench mouth or Vincent's angina
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Fusobacterum
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G- bacilli, elongated with tapered ends
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