Bchs Final

Front 1

Evolution is ongoing and is constrained by its past

Back 1

TRUE

Front 2

the most abundant chemical element in the human body dry weight is hydrogen

Back 2

FALSE

Front 3

The 23.1 ms equals 2.31 x 10 ^ 13 fs

Back 3

TRUE

Front 4

in the following reaction 4NH3( g)-> 2N2 (g) + 6 H2(g) the entropy

Back 4

Increases

Front 5

Which of the following are a pair of acid and conjugate base

Back 5

HA and A-

Front 6

what form of this amino acid cannot exist in any pH

Back 6

E

Front 7

what is the identity of the following organic functional group

Back 7

A) Ester

Front 8

which molecular structure below is the predominant form of aspartic acid at pH 1

Back 8

C)

Front 9

Entropy is a measure of...

Back 9

D) the disorder of a system

Front 10

what is the H+ concentration of .1 M HAc (PK = 4.7) if the pH is adjusted to 4

Back 10

B) 1e-4

Front 11

what is the pk of the weak acid HA if the solution containing 0.2 M HA and 0.1 M A- exhibits a pH of 6.5

Back 11

A) 6.8

Front 12

The length of the alpha helix of 20 amino acid residue is...

Back 12

A) 30 A

Front 13

which residues in the seven residue- repeat ABCDEFG of the alpha keratin helical wheel provide a hydrophobic interaction to associate two coiled coils?

Back 13

B) a,d

Front 14

The GFP structure is shown below. The major motif in this protein is...

Back 14

B sheets

Front 15

Back 15

A) aef

Front 16

The misfolding of amyloid beta protein leads to

Back 16

C) Alzheimers disease

Front 17

Back 17

Pig

Front 18

Spontaneous oxidation of the heme-bound Fe (II) to Fe(III) is prevented in hemoglobin by:

Back 18

C) The surrounding protein structure in each subunit

Front 19

For beta sheets the terms parallel and antiparallel refer to

Back 19

A) the direction of the associated peptide strands

Front 20

Back 20

B) [100-S-S-80] [100-S-S-70]

Front 21

Which of the following shows resonance structures

Back 21

Front 22

Protein x has an absorption extinction coefficient of 0.8 mL/mg*cm at 280nm. What is the absorbance of a solution with 2.0 mg/mL of this protein (the pathlength is still 1 cm)?

Back 22

A) 1.6

Front 23

What is the fractional saturation of myoglobin (YO2) at an oxygen partial pressure of 45 torr?

Back 23

E) 0.94

Front 24

An enzyme cannot make a reaction thermodynamically favorable

Back 24

A) TRUE

Front 25

Phase 2 clinical trails are focused on evaluating the safety of new drug candidates

Back 25

B) False

Front 26

The reaction coordinate graph shown below, which locations are intermediate states

Back 26

C) none of the above

Front 27

In the presence of a competitive inhibitor at [I]=3mM, the apparent Km is three times the Km for the uninhibited reaction. What is KI?

Back 27

C) 1.5 mM

Front 28

The role of water in the lysozyme active site is to:

Back 28

B) Regenerate the active form of the catalytic residues at the active site

Front 29

A 1st order rxn has t1/2 of 20min. What is the rxn rate constant k?

Back 29

C) 0.035 min^-1

Front 30

In a serine protease enzyme, the catalytic triad drawing in the order of the "proton shuttle network" is:

Back 30

B) Ser- His-Asp

Front 31

For the elementary reaction A+B->P, the correct rate equation and reaction order are

Back 31

D) v=kAB, it is a second order reaction

Front 32

Which of the following types of inhibition does this figure below reflect?

Back 32

B) uncompetitive

Front 33

Which of the following is not true about enzymes?

Back 33

Enzymes catalyze rxns in the forward direction only