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8 Cards in this Set

  • Front
  • Back
Proton gradient serves as an energy reservoir for the synthesis of ATP
Oxidative phosphorylation
the process by which NADH and QH2 are oxidized and ATP is formed
Respiratory electron-transport chain (ETC)
Series of enzyme complexes embedded in the inner mitochondrial membrane, which oxidize NADH and QH2. Oxidation energy is used to transport protons creating a proton gradient
ATP synthase
uses the proton gradient energy to produce ATP
Chemiosmotic theory
A proton concentration gradient serves as the energy reservoir for driving ATP formation
Respiration by mitochondria
Oxidation of substrates is coupled to the phosphorylation of ADP – don’t get oxidation when ADP is absent
Respiration (consumption of oxygen) proceeds only when ADP is present
The amount of O2 consumed depends upon the amount of ADP added
Coupled nature of respiration in mitochondria
(a) O2 consumed only with ADP, excess Pi - normal oxidative phosphorylation
(b) (+) Uncoupler DNP (O2 consumed without ADP) – oxidation reactions without conservation of energy into ATP
Uncouplers
stimulate the oxidation of substrates in the absence of ADP