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22 Cards in this Set
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- Back
Buprenorphine
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(partial opioid agonist) – opiate detoxification.
(subtex) Or formulation containing buprenorphine and naloxone (suboxone) available for outpatient. Greater safety of margin than methadone regarding safety margin |
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Tacrine
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(Cognex)
Anticholinergic used for alzheimers First line in treatment of neuroleptic induced parkinsonism and for acute dystonia CNS muscarinic antagonists s/e: blurry vision (cycloplegia), constipation, urinary retention, sedation and delirium |
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Galantamine
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(reminyl)
Anticholinergic used for alzheimers First line in treatment of neuroleptic induced parkinsonism and for acute dystonia CNS muscarinic antagonists s/e: blurry vision (cycloplegia), constipation, urinary retention, sedation and delirium |
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Rivastigmine
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(exelon)
Anticholinergic used for alzheimers First line in treatment of neuroleptic induced parkinsonism and for acute dystonia CNS muscarinic antagonists s/e: blurry vision (cycloplegia), constipation, urinary retention, sedation and delirium |
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Donepezil
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(aricept)
Anticholinergic used for alzheimers First line in treatment of neuroleptic induced parkinsonism and for acute dystonia CNS muscarinic antagonists s/e: blurry vision (cycloplegia), constipation, urinary retention, sedation and delirium |
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Selegiline
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MAOI type B
Increases extracellular DA in the striatum For parkinson dz/ parkinsonism/ dystonia S/e: hypertensive crisis, arrhythmias, orthostatic HoTN, compulsive behaviors, hallucinations, EPS, dyskinesia Avoid abrupt cessation |
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Duloxetine
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CYMBALTA
Heterocyclic antidepressant – SNRIs Inhibits NE and serotonin reuptake MDD, GAD, DM neuropathy s/e hepatotoxicity, seizures, SIAH, hyponatremia |
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Oxcarbazepine
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Anticonvulsants
And for bipolar d/o Blocks voltage-sensitive Na channels and stabilizes neural membranes, inhibits repetitive firing and decreases synaptic impulse propagation Check Creatinine at baseline Stevens-Johnson, thrombocytopenia, leukopenia, hyponatremia |
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topiramate
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(topomax)
Anticonvulsants Partial seizures, and Migraine HA s/e: nephrolithiasis, metabolic acidosis, osteomalacia and osteoporosis |
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Benztropine
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For parkinsonism and extrapyramidal rxns and dystonic rxns
Antagonizes acetylcholine and histamine receptors s/e: tachycardia, psychosis (anticholinergic), dry mouth, constipation, urinary retention |
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Diphenylhydramine
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Anxiolytic
Hypnotic/sleep med Useful for extrapyramidal sx and short term insomnia Nonselective antihistamine s/e: hemolytic anemia, agranulocytosis, pancytopenia, constipation, blurred vision |
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Amantadine
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For influenza, parkinsonism, extrapyramidal disorders
Potentiates CNS dopaminergic responses Check Cr at baseline |
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Naltrexone
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Mu opioid antagonist that is used to prevent alcohol relapse and to lessen the severity of relapse in pts with alcohol dependence.
Initiated once pt has been DETOXIFIED. At least 1 wk after last opioid exposure otherwise can result in withdrawal. Reduces alcohol craving. Best when combined with psychosocial interventions. |
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Clonidine
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CNS alpha 2 adrenoreceptor agonist. Presynaptic autoreceptor that inhibits release of CNS NE.
Primarily used as anti-HTN. Decreases autonomic symptoms. Treatment of ADHD and tourette’s syndrome may be useful for impulsiveness and other forms of behavioral dyscontrol. s/e include sedation, dizziness and HoTN. |
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Methylphenidate
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Ritalin
psychostimulant ADHD, narcolepsy, and some forms of depression Alteration of CNS monoamine function Facilitating endogenous NT release Labilities inducing tolerance and psychological dependence leading to abuse. S/e sympathomimetic: tachy, insomnia, anxiety, HTN and diaphoresis. |
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Dexmethylphenidate
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Dexedrine
A psychostimulant ADHD, narcolepsy, and some forms of depression Alteration of CNS monoamine function Facilitating endogenous NT release Labilities inducing tolerance and psychological dependence leading to abuse. S/e sympathomimetic: tachy, insomnia, anxiety, HTN and diaphoresis. |
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D and L amphetamine
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Adderall
psychostimulant ADHD, narcolepsy, and some forms of depression Alteration of CNS monoamine function Facilitating endogenous NT release Labilities inducing tolerance and psychological dependence leading to abuse. S/e sympathomimetic: tachy, insomnia, anxiety, HTN and diaphoresis. |
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Atomoxetine
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(Strattera)
ADHD Selective NE reuptake inhibitor. |
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Propranolol
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Anxiolytic
Beta blocker Alter behavior and mood states by altering both CNS and peripheral catecholamine function. Diminish central arousal Peripherally reduce tachycardia, tremor, sweating and hyperventilation. s/e: bradycardia, HoTN, asthma exacerbation and masking hypoglycemia. |
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Eszopiclone
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LUNESTA
Hypnotic/sleep med Interacts w/ GABA receptor complexes s/e: withdrawal if abrupt, amnesia, hallucinations, aggressive behavior, dry mouth, |
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Ramelteon
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ROZEREM
Hypnotic/sleep med Binds to melatonin MT1 and MT2 receptors (agonist) s/e: HA, nausea, diarrhea, dizziness, fatigue |
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Memantine
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(namenda)
Antagonist at the excitatory glutamatergic NMDA receptor. Approved for moderate-to-severe dementia of Alzheimer type. Antagonism of the NMDA receptor may help prevent glutamate-mediated excitotoxicity and improve function of neurons in some forms of memory. |