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36 Cards in this Set
- Front
- Back
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What are 4 example of reversible cell changes?
2 irreversibe? |
cell swelling, mitocondria swelling, plasma membrane blebbing, and fatty changes
Necrosis and apoptosis |
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what is primary intention in wound healing?
secondary intention? |
the surgical edges are closed
surgical edges are not closed |
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what are the first inflam cells to appear at a wound?
second? |
PMN
Macrophages |
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what are 3 things that occur with acute swelling?
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vasodialtion
increase in permeability emigration of lymphocytes |
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which parts of the inflam process depend on prostoglandins?
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pain, vasodialtion, fever
hence taking something that blocks prostoglandin production such as an NSAID does not stop inflammation completely. |
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what interleukin activates T-cells?
what interleukins activate B-cells? what IL activates PMNs? What IL activates NK cells? |
IL-1
IL-2,4,5 IL-8 IL-2 |
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what does alpha interferon do?
what does Beta interferon do? what does gamma interferon do? |
induces MHC-I expression
induces MHC-I expression Induces MHC-II expression |
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What IL causes fever?
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IL-1
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mutation to what receptor leads to SCIDs? (server combined immunodifficency)
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IL-2 receptor
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what is the classical oathway of complement convertase?
alternate pathway convertase? what are both of these convertase directed at doing? |
C4b2a
C3bBb cleavage of C3 |
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what is amyloid?
What disease is sig of AL AA AB |
eosinophilic extracellular substance that forms aggregates in B-pleated sheat?
MM chonic inflam alzheimers |
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what cell mediates type 1 hypersensitive reaction and what are 2 examples?
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IgE; asthma and anaphylatic reaction
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what cell mediates type 2 hypersensitive reaction and what is an example?
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IgG and M
transfusion reaction |
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what cell mediates type 3 hypersensitive reaction?
example? |
IgG and M
serum sickness |
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what is an example of a type 4 hypersensitive reaction?
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tuberculin reaction (TB test)
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Oncogenes:
C-myc C-abl ras BCL-2 |
burkitts lymophoma
CML (chonic myelogenous leuk) colon cancer non-hodgkins lymphoma |
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what are 2 tumor markers for prostate carcinoma?
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PSA and acid phosphatase
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is CF AD or AR?
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AR
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In albanism, do you still have melanocytes?
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yes, but they contain unpigmented malanosomes
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what do von willibrand disease, marfans, and ether danlos disease all have in common?
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AD
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someone with familial polyposis is at increased risk for what?
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colon cancer
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what are 2 tumor markers for prostate carcinoma?
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PSA and acid phosphatase
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is CF AD or AR?
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AR
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In albanism, do you still have melanocytes?
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yes, but they contain unpigmented malanosomes
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what do von willibrand disease, marfans, and ether danlos disease all have in common?
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AD
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what are 2 tumor markers for prostate carcinoma?
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PSA and acid phosphatase
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someone with familial polyposis is at increased risk for what?
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colon cancer
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is CF AD or AR?
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AR
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In albanism, do you still have melanocytes?
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yes, but they contain unpigmented malanosomes
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what do von willibrand disease, marfans, and ether danlos disease all have in common?
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AD
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someone with familial polyposis is at increased risk for what?
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colon cancer
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what type of anemia is someone susseptible to of they have G-6-P-DH def?
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hemolytic anemia
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what is duchenne MD?
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lack of dystrophin that results in musclular dystrophy
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what is chronic granulomatous disease?
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defect in PMN to carry out respiratory burst. Cannot make free radicals.
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what is turners syndrome?
what is kelinfelters syndrome? |
45 X
47 XXY |
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a partial deletion in these chromosomes results in what?
5p 11p 13q |
cri du chat
congenital absense of iris retinoblastoma |
