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10 Cards in this Set
- Front
- Back
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what are drugs that are easily displaced from albumin
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these are drugs that bind albumin but are easily knocked off
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Is a drug inactive or active when bound to albumin?
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inactive. the active is not bound to albumin
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what type of drugs more readily bind to albumin?
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hydrophobic
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what are drugs that induce p-450s and what might occur?
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these cause an increase in activity of p-450s. this may lead to less drugs in blood due to increase in metabolism
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what are inhibitor of p-450s and what might this cause
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decreased/inhibit p450s. this means there may be more drug in the body than expected bc of a decrease in metabolism.
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what is the pneumonic for drugs easily displaced from albumin?
drugs? |
serum proteins can spew
sulfonamides phenylbutazone coumadin sulfonyurease |
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what is the pneumonic for drugs that induce P450s
drugs? |
one pharmacutical brings about rapid liver metabolism
Oral contraceptives phenytoin barbituouts alcohol rifampin l-dopa methadone |
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what is the pnuemonic for drugs that inhibit p450s?
drugs? |
some pharmacutical classes inhibit drug metabolism
sulfonamides phenylbutazone chloramphenocol Isoniazid dicumarol cimetadine |
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what is the pneumonic for drugs that compete for renal transporters?
drugs? |
some pharmacuticals plus urate stop transporters
sulfonamides probenacid peni urate salicylates thiazides |
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what type of drug would you not want to give someone with gout?
what drug at high concentration is an exception to this rule? |
one that blocks renal tubules.
probenacid |
