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5 Cards in this Set
- Front
- Back
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Typical Antipsychotics :High Potency
-2 Receptor actions |
-High potency D2 antagonist
-Alpha1 antagonist |
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Typical Antipsychotics: Mid Potency
-4 Receptor action |
-mid potency D2 antagonist
-alpha 1 antagonist -H1 antagonist -Muscarinic antagonist |
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Typical Antipsychotics: Low Potency
-Receptor action |
-low potency D2 antagonist
-most potent muscarinic antagonist |
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Atypical Antipsychotics: Transmitter interaction Hypothesis
-State it |
-All atypical antipsychotics are both D2 and 5HT-2A antagonists
-Blockade of 5HT-2A on DA cell bodies causes an INCREASE in DA release -There are more 5HT-2A receptors in some areas than others |
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Atypical Antipsychotics: Transmitter interaction Hypothesis
-Effect in Cortex -Effect in Striatum -Effect in Pituitary -Effect in Limbic System |
Higher level of DA from block
-enhanced cognition, improvement in negative symptoms -improvement in EPS -Less prolactin release Maintained D2 Block -Improvement in positive symptoms |
