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58 Cards in this Set
- Front
- Back
cell membrane
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The semipermeable membrane that encloses the neuron.
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Dendrites
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The short processes emanating from the cell body, which receive most of the synaptic contacts from other neurons
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Axon hillock
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The cone-shaped region at the junction between the axon and the cell body
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Axon
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The long, narrow process that projects rom the cell body.
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Myelin
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The fatty insulation around many axons.
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Cell Body
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The metabolic center of the neuron. (aka Soma)
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Nodes of Ranvier
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The gaps between sections of myelin
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Buttons
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The buttonlike endings of the axon branches, which release chemicals into synapses.
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Synapses.
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The gaps between adjacent neurons across which chemical signals are transmitted.
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Endoplasmic reticulum
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a system of folded membranes in the cell body: either help with synthesis of fats or proteins
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Cytoplasm
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The clear internal fluid of the cell
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ribosomes
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internal cellular structures on which proteins are synthesized
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golgi complex
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a connected system of membranes that packages molecules in vesicles.
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nucleus
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the spherical DNA-containing structure of the cell body
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mitochondria
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sites of aerobic energy released
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microtubules
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tubules responsible for the rapid transport of material throughout neurons
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synaptic vesicles
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spherical membrane packages that store neurotransmitter molecules ready for release near synapses.
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neurotransmitters
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molecules that are released from active neurons and influence the activity of other cells.
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oligodendroglial
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In the CNS
Produces myelin to wrap around multiple axons |
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Schwann Cells
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in the PNS
One cell wraps itself to create myelin sheath |
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Astrocytes
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cover blood vessels
part of blood-brain barrier in CNS |
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Microglial
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travel around serving phagocytosis roles
engulfs foreign particles PNS and CNS |
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Spinal cord
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"like subway"
sensory information coming in and goes to brain from body motor information going out of brain and goes to the body. thicker in some areas and thinner in others thicker=info from extremities 31 total spinal nerves |
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Cervical part of spinal cord
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8 vertebrae
8 spinal nerves |
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Thorasic part of spinal cord
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12 spinal nerves
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lumbar part of spinal cord
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5 spinal nerves
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saccral part of spinal cord
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5 spinal nerves
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coccygeal part of spinal cord
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1 spinal nerve
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Autonomous Nervous system: PNS and SNS
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PNS: rest and digest
SNS: fight or flight |
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Sympathetic neurons
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long postganglionic neuron
short preganglionic neuron Ach and NE thoracic and lumbar area of spinal cord |
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Parasympathetic neurons
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long preganglionic neuron
short postganglionic neuron Ach cervical and sacral area of the spinal cord |
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Somatic Nervous system
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nerves as the approach the spinal cord
dorsal root- SENSORY ventral root- MOTOR |
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amygdala
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LIMBIC SYSTEM
temporal lobe emotions |
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hippocampus
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LIMBIC SYSTEM
post to anterior learning and spatial reasoning |
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Anterior thalamus
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LIMBIC SYSTEM
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Septal area
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LIMBIC SYSTEM
emotions "septal range" |
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Mamillary bodies
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LIMBIC SYSTEM
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cingulate gyrus
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LIMBIC SYSTEM
Limbic ring |
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Globus Pallidus
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BASAL GANGLIA
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Caudate Nucleus
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BASAL GANGLIA
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Putamen
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BASAL GANGLIA
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resting potential achieved in the membrane
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1. diffusion: high to low conc.
2. hydrostatic pressure: causes water level to equal outside 3. electrostatic pressure 4. semipermeable mem.: not everything can pass through |
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metabatropic receptors
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act through a secondary messenger usually a G protein for ions to pass through due to the binding of a neurotransmitter
muscarinic receptor: accepts Ach |
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ionotropic receptors
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(ligand) open cell membrane directly for ions to pass through due to the binding of a neurotransmitter
Nicotinic receptors: Accepts Ach nicatine |
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acetylcholine (Ach)
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degradation
at all neuromuscular junctions at most synapses in ANS two receptors: nicotinic and muscarinic |
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catecholamines:
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dopamine, NE, Epi
driven by tryosine |
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indolamines
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seratonine: tryptophan driven
NE: alpha and beta receptors dopamaine: has 5 receptors |
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Glutanic acid
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most prevalent excitatory transmitter in human brain
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GABA
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gamma-aminobutyric acid
most prevalent inhibitory transmitter in human brain |
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asparate
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excitatory
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glycine
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inhibitory
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peptides transmitters
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larger molecule
chains of amino acids together five subgroups: pituitary, hypothalamic, brain-gut, opiod, and misc. |
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unconventional transmitters
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NO and CO
short lived so hard to study endocannabinoids |
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Neurotransmitters created, activated, and deactivated
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1. NT molecules are synthesized form precursors under the influence of enzymes
2. NT molecules are stored in vesicles 3. NT molecules that leak from their vesicles are destroyed by enzymes 4. Action potentials cause vesicles to fuse w/ the presynaptic membrane and release their NT molecules into the synapse 5. released NT molecules bind w/autoreceptors and inhibit subsequent NT release 6. released NT molecules bind to postsynaptic receptors 7. released NT molecules are deactivated by either reuptake or enzymatic degradation. |
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Agonistic Drug Effects on NT
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!. drug increase the synthesis of NT: by increasing the amount of precursor
2. drug increases the number of NT molecules by destroying degrading enzymes 3. Drug increases the release of NT molecules from terminal buttons 4. drug binds to autoreceptors and blocks their inhibitory effect or NT release 5. drug binds to postsynaptic receptors and either activates them or increase the effect on them of NT 6. Drug blocks the deactivations of NT molecules by blocking degradations or reuptake |
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Antagonistic Drug effects on NT
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1. drug blocks the synthese of NT molecules by destroying synthesizing enzymes
2. drug causes the NT molecules to leak from the vesicles and be destroyed by degrading enzymes 3. drug blocks the release of the NT molecules from terminal buttons. 4. drug activates autoreceptors and inhibits neurotransmitter release 5. drug is a receptor blocker; it binds to the postsynaptic receptors anad blocks the effect of the neurotransmitter |
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Inhibitory post-synaptic potential
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IPSP
hyperpolarize cell mem. by maxing out the action pot. less likely than EPSP |
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excitatory post-synaptic potential
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EPSP
depolarize cell mem makes an action pot more likely |