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58 Cards in this Set

  • Front
  • Back
cell membrane
The semipermeable membrane that encloses the neuron.
Dendrites
The short processes emanating from the cell body, which receive most of the synaptic contacts from other neurons
Axon hillock
The cone-shaped region at the junction between the axon and the cell body
Axon
The long, narrow process that projects rom the cell body.
Myelin
The fatty insulation around many axons.
Cell Body
The metabolic center of the neuron. (aka Soma)
Nodes of Ranvier
The gaps between sections of myelin
Buttons
The buttonlike endings of the axon branches, which release chemicals into synapses.
Synapses.
The gaps between adjacent neurons across which chemical signals are transmitted.
Endoplasmic reticulum
a system of folded membranes in the cell body: either help with synthesis of fats or proteins
Cytoplasm
The clear internal fluid of the cell
ribosomes
internal cellular structures on which proteins are synthesized
golgi complex
a connected system of membranes that packages molecules in vesicles.
nucleus
the spherical DNA-containing structure of the cell body
mitochondria
sites of aerobic energy released
microtubules
tubules responsible for the rapid transport of material throughout neurons
synaptic vesicles
spherical membrane packages that store neurotransmitter molecules ready for release near synapses.
neurotransmitters
molecules that are released from active neurons and influence the activity of other cells.
oligodendroglial
In the CNS
Produces myelin to wrap around multiple axons
Schwann Cells
in the PNS
One cell wraps itself to create myelin sheath
Astrocytes
cover blood vessels
part of blood-brain barrier
in CNS
Microglial
travel around serving phagocytosis roles
engulfs foreign particles
PNS and CNS
Spinal cord
"like subway"
sensory information coming in and goes to brain from body
motor information going out of brain and goes to the body.
thicker in some areas and thinner in others
thicker=info from extremities
31 total spinal nerves
Cervical part of spinal cord
8 vertebrae
8 spinal nerves
Thorasic part of spinal cord
12 spinal nerves
lumbar part of spinal cord
5 spinal nerves
saccral part of spinal cord
5 spinal nerves
coccygeal part of spinal cord
1 spinal nerve
Autonomous Nervous system: PNS and SNS
PNS: rest and digest
SNS: fight or flight
Sympathetic neurons
long postganglionic neuron
short preganglionic neuron
Ach and NE
thoracic and lumbar area of spinal cord
Parasympathetic neurons
long preganglionic neuron
short postganglionic neuron
Ach
cervical and sacral area of the spinal cord
Somatic Nervous system
nerves as the approach the spinal cord
dorsal root- SENSORY
ventral root- MOTOR
amygdala
LIMBIC SYSTEM
temporal lobe
emotions
hippocampus
LIMBIC SYSTEM
post to anterior
learning and spatial reasoning
Anterior thalamus
LIMBIC SYSTEM
Septal area
LIMBIC SYSTEM
emotions
"septal range"
Mamillary bodies
LIMBIC SYSTEM
cingulate gyrus
LIMBIC SYSTEM
Limbic ring
Globus Pallidus
BASAL GANGLIA
Caudate Nucleus
BASAL GANGLIA
Putamen
BASAL GANGLIA
resting potential achieved in the membrane
1. diffusion: high to low conc.
2. hydrostatic pressure: causes water level to equal outside
3. electrostatic pressure
4. semipermeable mem.: not everything can pass through
metabatropic receptors
act through a secondary messenger usually a G protein for ions to pass through due to the binding of a neurotransmitter
muscarinic receptor: accepts Ach
ionotropic receptors
(ligand) open cell membrane directly for ions to pass through due to the binding of a neurotransmitter
Nicotinic receptors: Accepts Ach nicatine
acetylcholine (Ach)
degradation
at all neuromuscular junctions
at most synapses in ANS
two receptors: nicotinic and muscarinic
catecholamines:
dopamine, NE, Epi
driven by tryosine
indolamines
seratonine: tryptophan driven
NE: alpha and beta receptors
dopamaine: has 5 receptors
Glutanic acid
most prevalent excitatory transmitter in human brain
GABA
gamma-aminobutyric acid
most prevalent inhibitory transmitter in human brain
asparate
excitatory
glycine
inhibitory
peptides transmitters
larger molecule
chains of amino acids together
five subgroups: pituitary, hypothalamic, brain-gut, opiod, and misc.
unconventional transmitters
NO and CO
short lived so hard to study
endocannabinoids
Neurotransmitters created, activated, and deactivated
1. NT molecules are synthesized form precursors under the influence of enzymes
2. NT molecules are stored in vesicles
3. NT molecules that leak from their vesicles are destroyed by enzymes
4. Action potentials cause vesicles to fuse w/ the presynaptic membrane and release their NT molecules into the synapse
5. released NT molecules bind w/autoreceptors and inhibit subsequent NT release
6. released NT molecules bind to postsynaptic receptors
7. released NT molecules are deactivated by either reuptake or enzymatic degradation.
Agonistic Drug Effects on NT
!. drug increase the synthesis of NT: by increasing the amount of precursor
2. drug increases the number of NT molecules by destroying degrading enzymes
3. Drug increases the release of NT molecules from terminal buttons
4. drug binds to autoreceptors and blocks their inhibitory effect or NT release
5. drug binds to postsynaptic receptors and either activates them or increase the effect on them of NT
6. Drug blocks the deactivations of NT molecules by blocking degradations or reuptake
Antagonistic Drug effects on NT
1. drug blocks the synthese of NT molecules by destroying synthesizing enzymes
2. drug causes the NT molecules to leak from the vesicles and be destroyed by degrading enzymes
3. drug blocks the release of the NT molecules from terminal buttons.
4. drug activates autoreceptors and inhibits neurotransmitter release
5. drug is a receptor blocker; it binds to the postsynaptic receptors anad blocks the effect of the neurotransmitter
Inhibitory post-synaptic potential
IPSP
hyperpolarize cell mem. by maxing out the action pot.
less likely than EPSP
excitatory post-synaptic potential
EPSP
depolarize cell mem makes an action pot
more likely