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4 Cards in this Set
- Front
- Back
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cholestyramine
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binds bile acides in intestinal lumen
-10-35% reduction in LDL. |
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niacin
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inhibits liplysis at adipose tissue
->DECREASED SECRETION OF VLDL AT LIVER -use for all hyperlipidemias with high VLDL/LDL and LOW HDL 15-25 reduction LDL 15-40 VLDL 30-50 TG **15-30 increase HDL |
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gemfibrozil
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nuclear transript receptors mainly in LIVER AND BROWN ADIPOSE
increased syntheses of LPL ***30-60% reduction of TG 20-30 VLDL 5-10 HDL |
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ezetimibe
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brush border, selective inhibition of cholesterol
15-20 LDL 5-8 triglyc 16 reduction in Apo-B i.e. NBD really.. but -***synergistic LDL reduction with |
