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4 Cards in this Set

  • Front
  • Back
Direct agonist
A chemical that directly stimulates a neurotransmitter receptor.

Apomorphine turns on d1, d2, and d3 receptors
Indirect agonist
Increases the amount of neurotransmitter in the synaptic cleft through non-receptor mediated processes

Amphetamine reverses the direction of the DA TRANSPORTERS
Cocaine blocks DA transporters
Direct antagonist
Physically blocks the receptor site so that neurotransmitter cannot act

Haldol binds to both pre and post-synaptic DA receptors
Indirect antagonist
Act to indirectly decrease the amount of neurotransmitter in the synaptic cleft

Reserpine dissolves vesicles, making DA free-floating in terminal and vulnerable to MAO