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4 Cards in this Set
- Front
- Back
Direct agonist
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A chemical that directly stimulates a neurotransmitter receptor.
Apomorphine turns on d1, d2, and d3 receptors |
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Indirect agonist
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Increases the amount of neurotransmitter in the synaptic cleft through non-receptor mediated processes
Amphetamine reverses the direction of the DA TRANSPORTERS Cocaine blocks DA transporters |
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Direct antagonist
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Physically blocks the receptor site so that neurotransmitter cannot act
Haldol binds to both pre and post-synaptic DA receptors |
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Indirect antagonist
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Act to indirectly decrease the amount of neurotransmitter in the synaptic cleft
Reserpine dissolves vesicles, making DA free-floating in terminal and vulnerable to MAO |