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20 Cards in this Set
- Front
- Back
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Barbituates proceed more rapidly through
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Stage II anesthesia
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Barbituates produce
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Sedation
Hynosis Anesthesia Death (in that order) |
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Hynosis
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sleep
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Barbituate MOA
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potentiates GABA
increases Cl concentration hyperpolarizes cell Inhibition of AP |
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Barbituates are all
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controlled substances
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Thiopental
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shortest duration
No longer available - cpaital punishment |
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Effects of barbituates on CNS
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depression
inhibition Decrease of seizures |
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Effects of barbituates on muscles
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relaxation
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Effects of barbituates on liver
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induce cyp450
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Effects of barbituates on fetus
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cross placenta
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Do barbituates produce analgesia
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NO!!!
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Thiopental
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Barbituate
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Pentobarbital
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Barbituate
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Phenobarbital
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Barbituate
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Barbituates can cause what complication
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perivascular administation
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Barbiturate anesthesia is terminated by
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physical redistribution
Brain to muscle to adipose tissue Then metabolized |
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How the barbituates _____ determines its ______.
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redistributes
duration |
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Metabolism varies between barbituates by
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nothing
All metabolized the same |
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If patient has less body fat the barbituate stays in
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the brain longer - prolongs effect
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Obesity effects duration how?
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redistributes to larger area so doesn't last as long
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