Bacteriology Exam Ii Corynebacteria Begins At Pg 58 In Ppts

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-pleomorphic
-Gram +
-aerobic rods
-inder Actinomycetes

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Corynebacteria

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cause pyogenic infection

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Corynebacteria

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pyogenic typically refers to

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-- an infection characterized by severe local inflammation, usually with pus formation

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Corynebacteria may appear as

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Chinese letters

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Corynebacteria are all susceptible to what in VITRO?

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Penicillin

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new name for Corynebactera Equi=

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Rhodococcus Equi

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Corynebacteria are often referred to as?

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diphtheroids

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Name three important species of corynebacteria:

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1.C.Diptheria
2.C.Renale Group
3. C.Pseudotuberculosis

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C.Diptheria causes:

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human diptheria..not significant in animals

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C. Renale group causes:

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urinary tract infection in cattle

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C. pseudotuberculosis causes:

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caseous lymphadentis in sheep & goats

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What is Caseous Lymphadenitis of sheep and goats ? Remember causeous lymphadenitis is a symptom from the c. Pseudotuberculosis species..(one of the main 3)

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a chronic, slowly progressive disease, characterized by extensive caseous necrosis and abscessation of lymph nodes
-also "Thin Ewe syndrome and Ulcerative Lymphangitis in horses"

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Pyelonephritis in cattle:

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C.Renale Group

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tell me a little about pyelonephritis in cattle..

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-healthy buuls carry
-transmitted by urine splash
-adhere with pili, f-up bladder,ureters,kid,-->production of urease--->ammonia-->tissue damag
inflammation-->purulent blood stained urine

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Diagnosis for C. Renale group you would do what?

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-examine urine sediment (Grams culture)
-isolate cow
-destroy bad bedding

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Memory device :"Renale"...

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Renale=RENAL problems

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Posthitis(pizzle rot, sheath rot)/ulcerative blano-posthitis in sheep & goats is mainly caused by ?

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C. Renale

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if C.Renale what would we do regarding feed and why?

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switch FROM legume to grassy/mixed hay B/C want to feed LESS protein

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ok so tell me which Corynebacteria species/group I'm talking about...organism present on skin, gets wounded during shearing or inhalation-->

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C. PSEUDO-tuberculosis

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tell me what the cultures look like in c.renale & c. pseudotuberculosis

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C.Renale=pleomorphic Gram+ RODS with yellow or white colonies,+ve catalase& urease

C.Pseudo-tuberculosis=small white DRY colonies with late (>72 hr) hemolysis...ELISA test is used to screen these animals for C.pseudo-tuberculosis before they're imported

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If you got a farm with a little C.pseudo-tuberculosis on it (or u just want to be a good farm manager) how would you go about your shearing process?

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Shear YOUNG first, CULL those with abscesses...THAT MEAN SELL their ass.

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tell me about vaccines/therapy regarding C.pseudo-tuberculosis

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-Autogenous vaccines/bacterins (a suspension of killed or attenuated bacteria for use as a vaccine) are partially effective...THERAPY is usually INEFFECTIVE

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which Corynebacteria would you see skin injury-->infect abcess lymph nodes-->green pus -->concentric onion like layer (fyi...concentric means basically circles w/in a circle)

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C. Pseudo-tuberculosis

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Rhodococcus equi formorly called?

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Corynebacterium equi

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Rhodococcus equi is gram...?

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POSITIVE coccoid or short/pleomorphic rods

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Rhodococcus equi looks like what on BA

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muccoid, pale pink (salmon-pink), NON-hemolytic colonies...in BA

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habitat for Rhodococcus equi..

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soil,barn...anything contaminated with horse manure..also the horses intestines

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Who is most suseptable to Rhodococcus equi?

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foals 6wks age(2-4 month olds) most susceptible

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Rhodococcus equi disease causes?

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suppurative (fyi suppurative means: The formation or discharge of pus.) bronchopneumonia of foals causes abscess in older foals.

(rarely pigs, humans,cats..)

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Rhodococcus equi symptoms

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-dyspnea (means shortness of breath for all u dummies)
-coughing
-anorexia
-ultimately emaciation
(course is 1-2 weeks, prognosis poor in foals)

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Rhodococcus equi diagnosis...what would you do to check and see if this is what you think the symptoms are pointing to?

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Radiography,
-culture (transtracheal aspirate)Grams.
-HISTORY of farm,age of foal,clinical sighs
(remember culture morphology salmon pink muccoid colonies)

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Rhodococcus equi pathogenisis...for the dummies, I'm asking how does this disease develop.

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-Facultative intracellular parasites
(these are are capable of living reproducing inside or outside cells.)

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how to prevent Rhodococcus equi

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duh..remove/spread manure,dust control...

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how to treat OUTBREAK of Rhodococcus equi...

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Erythromycin + Rifampin > or equal to 4 weeks

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Prophylactic measures Rhodococcus equi...

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(again for you dummies prophylactic means "protective or preventative measures"...) --give Pen G to newborn foals

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What else can you do in controling/treatment of Rhodococcus equi?

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admin hyperimmune serum (from dam or other source) to foal 2-3 weeks of age

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Are there commercial vaccines for Rhodococcus equi

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NOPE