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19 Cards in this Set

  • Front
  • Back
prokaryotic cell

bacteria


nucleus is absent but have nucleoid(aggregate of dna)


contain smaller ribosomes 70 s


no other organells


cell wall rigid and contain peptidoglycan


no histone


no introns


mono and polycistrons mrna(messenger that encodes 2 or more proteins)


transcript and translation is coupled


N-formyl methionine is the AA initiating protein

eukaryotic cells

nucleus is present


multiple chromosomes surrounded by nuclear membrane and uses mitotic apparatus


cell wall flexible and contains sterols


cytoplasm-membrane bound organ cells eg mitochondria and lysosomes


methionine is the AA initiating protein

cellular arrangement

pneumococci-- arranged in pair


streptococci- - arranged in chains


bacilli- arranged in chains


stap-- arranged in four groups


staph cocci- arrange in cluster


Chinese leter- corynebacteria

plasmid

double stranded, circular DNA


carried genetic info which mediates: antibiotic resistance to heavy metals, silver


resistance to uv light



cell wall functions

energy generation by oxidative phosphorylation


lipid bilayer

peptidoglycan is a

lipid mesh made up of ropelike linear polysaccharide


polysaccharide is made up of repeating: N-acetylglucossamine(GlcNAc, NAG, G) and N- acetylmuramic acid (MurNAc, NAM, M)

LYSOZYME
degrade peptidoglycan
vancomycin
INHIBITS ENLOGATION OF PEPTIDOGLYCAN CHAINS
B-LACTAM
inhibits cross linking reaction
BACITRACIN
inhibits recycling of bactoprenol carrier
GRAM positive

90% peptidoglycan with teichoic acids(antigenic in nature)



teichoic acids

glycerol phospae or ribitol phosphate are located in the outer layer of the gram positive cell wall and extend from it


mediccaly it iduce septic shock and attachment of staphylococci to mucosal cells

GRAM NEGATIVE

10% peptidoglycan, LPS aka endotoxin


LPS consist of 3 structure lipid a, CORE POLYSACCHARIDE, and O antigen

ACID FAST CELL WALL

because of its unique cell wall it


resist decolorization with acid-alcohol


stains red, initial color is carbol fuchsin



flagella

made of flagellin


helps in chemotaxis(bacteria moving towards nutrient)





niesseria gonorrhoeaee
adheres specifically to the human cervical or urethral epithelium

endospores

higly resistant , dipicolinic acid


formed by gram positive


BACILLUS ANTHRAX


CLOSTRIDIUM(including tetanus and botulism)


killed at 121 celicius


they have thick keratin like coat


ANTIBIOTICS are ineffective

glycocalyx

slime layer, secreted by bacteria,


eg streptococcus mutan adheres to teeth forming plaques