Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
305 Cards in this Set
- Front
- Back
|
Aerobes |
Nocardia Mycobacterium Tuberculosis Pseudomonas |
|
|
anaerobes |
Fusobacterium Clostridium Bacteriodes Actinomyces |
|
|
non gram staining |
legionella chlyamdia treponema ricketssia mycobacterium mycoplasma (sterols) ureaplasma |
|
|
encapsulated bacterium |
e coli strep pneumo psuedomonas klebsiella hib salmonella gbs |
|
|
giemsa stain |
intracellular: chlamydia trypanosomes rickettsia borrelia plasmodium |
|
|
PAS |
glycogen stain Treponema whippei (Whipples disease) |
|
|
Ziehl Neelsen (carbol fuchsin) stain |
Acid fast Mycobacterium Nocardia Cryptosporidum oocyst |
|
|
India ink |
Cryptococcus neoformans |
|
|
silverstain |
Legionella Fungi Helicobacter pylori |
|
|
thayer martin culture |
vancomycin colistin nystatin Trimethoprim Nesseira |
|
|
tellurite |
corynebacterium diptheria |
|
|
loffler medium |
cornyebacterium |
|
|
lowenstein jesen |
mycobacterium |
|
|
eaton agar |
mycoplasma |
|
|
sabouraud |
fungi |
|
|
obligate intracellular |
rickestia chlamydia coxiella |
|
|
encapsulated |
e coli strep pneumo haemophilus influenza b salmonella klebsiella GBS psuedomnonas |
|
|
urease positive |
cryptococus h pylori proteus ureaplasma nocardia klebsiella s epidermis s saphryophytics |
|
|
catalase positive |
nocardia psuedomonas listeria aspergillus candida e coli staphyloccci seratti |
|
|
type III |
e coli pssuedonomas salmonella shigella |
|
|
ef2 inactivation |
diptheria beta prophage psuendomas exotoxin a |
|
|
inactivate 60 via remoing adenine from rRNA |
shigella EHEC O157:h7 |
|
|
increase camp |
etec HLT: overactivates adenylyl cyclase increase cl secretion in gut baciilus atrnacis: mimics adelyate cyclase to increase camp V cholera: overacitvates by permanelty actvating gs: increase cl secretion Bodetella persuttis: increase adelyate ccylase via disabiling gi |
|
|
increase cgmp |
hst of etec: decrease na absorption |
|
|
etec hlt |
overactivates adenlylate cyclase increase camp increase cl seccretion |
|
|
etec hst |
overactivates guanylate cyclase increase cgmp deccrease na absorption |
|
|
edema toxin of bacillus |
mimic adylate cyclase to increase cgmp |
|
|
cholera toxin |
permanently activates gs to activate adenylate cyclase increase cl secretion |
|
|
pertussis toxin |
increase camp via gi inhibiiton to prevent phagocytosis |
|
|
clostridium tetani |
snare prevent ach from inhibitory neurons gaba and bylcine from renshaw |
|
|
clstodirum toxin |
alpha toxin lecthicinase decreagade tissue |
|
|
specliazed lysogenic phase |
shiga like toxin botlinum toxin cholera toxin ditperha toxin erythgeonic toxin of step pyogesnes |
|
|
parvo in adults |
mimics rheumtoid arhtiritis |
|
|
GRAM + LPS stimulator |
LIPTEICHOIC ACID IN CELL WALL |
|
|
gram - lps stimulator |
lipid A |
|
|
o polysaccharide |
ag for gram - |
|
|
spore producing |
clostriduium bacillius coxiella |
|
|
glycocalyx |
polysaccharide network |
|
|
only gram - without endotoxin |
bacteroidies |
|
|
only gram + with endotoxin
|
listeria |
|
|
single polar faglella |
v cholera campylobacter jejuni |
|
|
mutiple falgella |
escherichia coli proteus mirabilis |
|
|
gram + with rods and spores |
bacillus clostridium |
|
|
Do not gram stain well |
treponema chlamydia mycoplasma mycobacterium ricketssia legionellla |
|
|
vancomycin trimethoprim colistin nystatin |
thayer martin for Neissiera |
|
|
Bordget Gengou agar (potatos) Regan Lowe (charcoal bloood abx) |
Bordetella pertussis |
|
|
aerobes |
nocardia pseudomonas Mycobacterium |
|
|
faculative intracellularlar |
salmonella neiseria brucella mycobacterium listeria francisella legionalla yersinia |
|
|
take up naked DNA |
transofrmation |
|
|
transformation bacteria |
strep penumonaeia h influx Neissiera |
|
|
Conjugation f+ X F-: |
singel strand of plasmid DNA transfered across conjugal bridge No chromosomal transfer |
|
|
HfrxF- |
F plasmid incorporates into bacterial chromosonal DNA Transfer for plasmid and chromosomal genes |
|
|
Generalized transduction |
Lytic phage infects bacterium cleave of bacterial dNA Transfer of genes via packaging of said genes |
|
|
Specialized transudction |
Lysogenic phage infect bacterial and viral DNA incorporated into bacterial DNA, when phage DNA is excited falnking DNA can be incorporated and packaged |
|
|
lysogenic phage have |
shia like toxin botolinum toxin cholera toxin diptheria toxin erythogrgenic toxin of strep pygoenus |
|
|
novobiocin |
staph saphrophytiucs Resistant Epidermis sesntitive |
|
|
optochin |
Optocin reistant: step viridans optochin sensitive streppneumoni |
|
|
bacitracin |
GBS Resistant GAS sesntivei |
|
|
alpha hemolytic |
strep penumoni strep viridans |
|
|
beta hemolytic |
listera step pyogenes strep agalactidae staph aures |
|
|
protein A for staph aureus |
binds fc portion of IgG prevent complement activation |
|
|
Panton Valentine leukocidin |
neutrophil and macropahge destruction |
|
|
lancet shaped gram + diplococcic |
strep penumoniae encapsualted IgA protease |
|
|
rusty sputum capsulated |
strep penumoniae |
|
|
makes dextrans |
strep sanuinis of strep viridans |
|
|
Pyrrolidonyl amrylamidase + PYR |
strep pyogenes |
|
|
scarlet rash withs andpaper like texture strawberry tongue cirumoral pallor subsequent desquamtion |
strep pyogenes gas |
|
|
cAMP factor |
enlarges area ofh emolysis by s aureas GBS |
|
|
Hippurate test + |
GBS |
|
|
metachormatic blue and red granules +elek test +chinesse letters |
corynebacterium ditpheria |
|
|
dipicolinic acid |
spores |
|
|
toxin a of c difficile |
enterotoxin binds brush border |
|
|
toxin b clostiridum difficle |
cytoskeletal disruption via actin depolymerization |
|
|
recurring c dif |
fidaxomicin |
|
|
painless with central necrosis black eschar |
cutenaeous athrax |
|
|
emetic type b cerues |
nausea and vomti within 1-5 hours preformed toxin cereulide |
|
|
diarrype type b cerues |
non bloddy diarrhea dn gi pain wtihin 8-18 hrs |
|
|
cold meets and unpastuerized diary products transplancental vagina transmission |
listera monocytogenes |
|
|
rocket tails of actin tumbling motility |
listeria monocytogenes |
|
|
listeria monocytegenes |
speticmemia spoteanous abortion granulomatous infantispetica neonatal menigiitis menigitis in immunoty compromised mild gasterogenteries |
|
|
cord factor mycobacterium tuberculi |
virulent strains inhbit macrophage maturation and induce release of tnf alpha |
|
|
sulfatides mycobacteria |
inhibit phagolysosomoal fusion |
|
|
lepromatous mycobacterium leprae |
th2 communciable |
|
|
tuberculoid mycobacterium leprae |
th1 noncommunicable |
|
|
tuberculoid tx |
dapsone rifampin |
|
|
lepromatous form tx |
clofazimine |
|
|
slow gram - rod fermenter |
citrobacter serratia |
|
|
fastf ermenter lactose gram - rod |
e coli enterobacter kelbieslla |
|
|
no lactose fermenting oxidase + |
psuedomonas |
|
|
no lactose fermenting hs2- |
shigella |
|
|
no lactoase fermeneting gram - rod with hs2 |
salmonella porteus yernia |
|
|
oxidase + comma shape alkaline media |
v cholera |
|
|
oxidase + comma shaped urease + |
h pylori |
|
|
oxidase + comma shaped 42 degree growth |
campylobacter jejuni |
|
|
beta galactosidase producer |
e coli |
|
|
polyribosylribitol phosphate |
haemophilus influneza type b capsular polysaccahraide |
|
|
legionella labs |
hyponatremia urine positive for ag |
|
|
legionaires diasease |
severea unilara and lboar pneumoniae fever gi and cns symptoms with bradicardia |
|
|
non sortibal fermentating gram - rod |
ehec |
|
|
anemia thrmobcytoepnia a cute renal failure |
hus |
|
|
dark red current jelly sputum llobar pneumoniae |
diabeteis and alcohol klesiella |
|
|
corkscrew motility |
campylobacter jejuni |
|
|
reactive arthitis and bacteria |
campylobacteria slamonella shigella |
|
|
specific invasion of m cells |
salmonelal except s typhi |
|
|
slamonelli typhi |
v1 capsule require large inoculum: senstiive to gastric acid |
|
|
salmonelli typhi vaccine |
live attenuated bacteria oral and IM vaccine vi capsule |
|
|
rose spots on abdomen, abdominal pain constpation fever |
salmonella typhi |
|
|
gram - coccobacillli with + bipolar stain |
yersinia entercolitica |
|
|
aniline dye stains |
write or giemsa only visualize borreli |
|
|
leptospira |
spiral shaped bacteria with axial fialments |
|
|
flu like symptoms
myaglias jaundice photophobia conjuctive suffision (erythema without exudate) +surfers |
leptospirsosis |
|
|
jaundice
azotemia liver and kidney disfuction fever hemorrage anemia contact with animal urine |
wiel disease leptospirosis |
|
|
ixodes deer tick |
borreli burgodrifi anaplasma basbesia |
|
|
lyme disease early |
erytehma conhronicum migrans flu like symptoms facial nerve palsy |
|
|
lyme diseae later |
monoarthitiis migratory polyarhittis cardiac av nodal block facila nerve plasy ponly nueroatphy |
|
|
rash on palsma nd soles |
2 spyhillus rocky moutin spotted fever coxsackie virus a kawazaki disease |
|
|
louse |
borreli recurrentis relapsing fever ricketsi prowazeki- epidemic typhus |
|
|
unpasteruzied dairy |
brucella |
|
|
ambylomma tick |
erchilosis |
|
|
animal urine |
leptospirosis |
|
|
dermacentor |
ricketsia rickettisi |
|
|
fleas |
ricketsi typhi - endemic typhus bubonic plaque yersinia |
|
|
rash starting from wrists and ankles spreading to trunk palsms and soles head ache, fever, rash |
rocky mountain spotted fever ricketsia ricketsssi |
|
|
fever headache rash on trunk spreading out centrally avoiding hands and soles |
ricketssia typhus endemic fleas epidemic louse (r. prowazeki |
|
|
monocytes wtih morulae in cytopalsma |
erclichiosis (ambylomma) |
|
|
granuloctes wtihi morulae in cytoplasma |
anaplasmosis (ixodses) |
|
|
pneumoniae culture - endocarditis |
coxiella |
|
|
reactive arthitis |
yersinia chlamydia salmonela shigella campylobacter |
|
|
small painless ulcers on genitals turning into sowellen painful ingiuinal lymph nodes that ulcerate |
chalmydia trachimonias serovar l1-l3 |
|
|
tinea bacterium |
microsporum trichophyton epidermophyton branching septae hyphae on KOH with blue fungal stain |
|
|
microsporum canis |
erytematous scaling rings with scaling central clearing |
|
|
sphaghetti an dmeatballs
summer weather hypopigementation fo skin |
malassezia tx: selenium sulfide |
|
|
germ tubes can contaminate cultures |
candidia apbicans |
|
|
fungus ball acute 45 degree angles |
aspergilliusfumigatus |
|
|
crytococcus neoformas |
+ india ink = sabourad sagar =mucicarmine poly saccharide capsule latex agglutinatino test: pooly saccrid ag |
|
|
soap buggle in brain +india ink +mucicramine |
crytopcocus neoformas |
|
|
back necrotic eschar on face with peentraiton of cirbiform plate |
muco or rhizopus with rireggular broad nonspetae hayphae with wide angles |
|
|
ground glass pneumoniae +disc shaped yeast on methanamine silver stain |
pcp |
|
|
cigar shaped budding yeast draiing lymphatics |
sporothrix scheneckki |
|
|
tx for sporothrix schenckii |
Kidoide |
|
|
bloating flatulence, fatty stools fooul smelling |
giardia cyst in water with traophozeis or cyst in stool |
|
|
blodoy diarhea with faslk shaped ulcer and ruq pain |
cyst in water seroglogy with trophozites wth rbc in cytopaslms |
|
|
severe diarrhea in AIDS |
oocyst in water crytposporidum |
|
|
choriorenittnis hydrocephalus intracrnaial calficiations |
txoplasma |
|
|
tx for toxoplasma sulfadiazinze pyrmethamine |
tsete fly painful bite tyrpanoma brucei |
|
|
naegleria fowleri |
rapid fatal menigoencphilitis |
|
|
fever head ache anemia splenomegally |
malaria 48 hour cycle: vivax/oale doment form in liver falciparum irregular patterns malarise 72 horus |
|
|
maltese cross in rbc with fever and hemolytic anemia |
ixodes tick trasnmite babesia |
|
|
enterobius vermicularis tx |
bednazole |
|
|
hook works ancyclostoma duodenale necator americanus tx |
bendazole |
|
|
fever vomit periorbal edema myaglia post infeciton with |
trichenlla tx bendazoles |
|
|
diethylcarbamazine tx for |
wuchereria bancrotfit and loa loa |
|
|
black skin nodules hyperpigement skin and river blindness |
onchocerca volvulus |
|
|
ingeisted nematodes |
enterobius ascaris toxocara trichennlla |
|
|
cutenaous infection nematodes |
strogyloides ancylostoma necator |
|
|
bites nematode |
loa loa onchocerca voluvlus wucehrecia bancrotfti |
|
|
praziquantel tx for |
diphyloobathroium and taenea solium |
|
|
albedazole tx for egg ingestion |
echinococcus |
|
|
squamous cell cancer of bladder |
schistoma haemtobium |
|
|
cholagiocarcionam post ingestion fo undercooked fish |
cholrchis sinesis |
|
|
microcytic anemia |
ancylostoma necator |
|
|
vit b 12 decienty |
diphylobothrium labtum |
|
|
brain cyst seizures |
taenia solium |
|
|
bilitary trac disease and cholagiocarcionma |
clonorchis senensis |
|
|
recombination |
exchange between 2 chromosomes by crossing over with enough sequence homology |
|
|
reassortment |
segment genomes |
|
|
complmentation |
mtation + no n fx porgeny still have nonfx protein |
|
|
phenotypic mixing |
2 virus infect same host cell mix of progeny genetic materia of progeny has not change,d only surfACE PRTEIN, PROGENY WILL RETURN TO PARENT |
|
|
live attentuated viruses |
influenza nasal mmr vzv rotavirus sabin polio small pox yellow fever |
|
|
killed |
rabies influenza im polio salk hep a |
|
|
subunit |
hbsag
hpv 6,11, 16, 18
|
|
|
naked rna viruses |
reovirus calicvirus hepe virus picorna |
|
|
naked dna viruses |
adenovirus parvovirus polyomavirus papillomvirus |
|
|
+ ss srna and dsdna infections ss+RNA |
retroviruses togaviruses flavivirus corona virus hepevirus calicvirus picorna viruses |
|
|
HBV dna |
partislaly ds and cicurlcate with Reverse transcriptase |
|
|
conjcutiviits post uri outbreak of red ees and cverical lymphadenoatpy |
adenovirus |
|
|
breakbone fever retroorbial ha muscle join pain with increase capillayr fragility test can progress to hemmorahtic fever |
dengue fever |
|
|
severe muscle weakness flacid palarysis like polio |
west nile virus |
|
|
black vomittus and councilment bodies coffe ground emesis |
yellow fever virus aedes osquito |
|
|
winter diarrhea |
reo virus rota virus |
|
|
parvovirus child |
transient apalstic nameia in sickle cell erythema infectosum 5th diease adult : inflatmor arhtitis like rf |
|
|
shift versus drift |
epidemics drift shift: reassortment of viral genus pandemics |
|
|
rubella |
toga virusa fever posteraurical arthisia dn fine rash |
|
|
infant infection with rubella |
pda sensorinueral ndeafness and cataracts |
|
|
mother infection iwth rubella
|
deafness menigitis penumonia lowg rade fever |
|
|
winter month infections |
influenza rotavirus rsv |
|
|
summer months infecionts |
enteroviruses polio echovirus excakie arboviurses |
|
|
cough coryza conjucitivtiis to blue grey spots on buccal mucase maculopapular rash on head and body |
measelse r/o HHV6 roseola |
|
|
borchioitics in babies in winter |
rsv |
|
|
supplment iwth mealses infections |
vit a |
|
|
mumps |
paramysox parotitis ocrhitits mengiittis |
|
|
ebola |
person to person transmission with nonspefici signs to v/d fluid class death |
|
|
aspetic menigitis casues |
coxsakcie echoviruses enteroviruses mumps |
|
|
window period |
antiHBc |
|
|
HIV gnem |
diploid 2 moleulces of RNA |
|
|
env HIV |
gp 120 and gp 41 cleavage of gp 160 to form envoleop glycproteins |
|
|
gp 120 |
attach to cd 4 t cell |
|
|
gp 41 |
fusion adn entry |
|
|
gag p 24 |
capsid protein |
|
|
pol
|
reverse trascirptase aspartate protease integranse |
|
|
macrphage and t cell invasion |
ccr5 macrhoages cxcr4 t cells |
|
|
AIDS |
cd4 count < 200 or cd4% %14 with aids deining illness |
|
|
bacillary aniomatosis versus kaposi sarcoma |
neutrophil lymph in bartonella lymphocytic infltrate hhv8 |
|
|
mutliplering enahncing leasons in mri |
toxoplasma |
|
|
cns lymphoma single ring enhancing lesions |
b cell lymphomaa
b cell infeciton by ebv |
|
|
oval yeast cells whtin macrophages |
histplasmaosis captlusm |
|
|
meingitis in hiv |
cyrpotocuccus neoframs |
|
|
retinitis |
cmv < 50 cotton wooll spots |
|
|
colon bactera |
bateroidids fragillus > e coli |
|
|
dare care outbreaks of bloody diarrhea iwth spuedoappeicitisi |
yersinai enteroclitical |
|
|
bloody diarrhea |
shigella salmonella eiec yersina enteroclitica ehec enatboma histolytica camplyobacter jejuni |
|
|
watery diarrhea |
rota virus norovirus adenovirus vibrocholera protozoa entarotoxigenic e coli clostridum perfigens clostiridlue difficle |
|
|
atypical pneumonia |
mycoplasma legionella hlmadia |
|
|
most common causes of puenuma children |
rsv mycoplasma chlymida trahcomosotos |
|
|
oval shaped vesciles on plams and soles vesiclesand ulcers in oral mucosa |
xocsakie tpye a |
|
|
high fever rose colored macules appear on body |
hhv6 |
|
|
cough coryza conjjutnifivitis blue white koplik splots rash begining at head and moving down |
measles |
|
|
slapped cheek |
erythema infectosis barvob 19 |
|
|
pink coasleicing macules begining at head and moving down fine desquamting truncual rash with psteiorr auricular lyphadneopathy |
rubella |
|
|
sand paper liker rash erhtaous with fever adn sore throt red toungue |
gas |
|
|
vescular rash on trunk spreading to face with varying lesions |
vzv |
|
|
painful ulcers in gentials |
chanroid h. ducreyi genieticla herpes hsv |
|
|
school of fish on cultures |
h ducreyi |
|
|
trichonominas |
strawberry red cervix |
|
|
intrasvascular cathethers |
saureus |
|
|
organ transplant recipient |
CMV |
|
|
amoxicillin and ampicillin uses |
haemophilus influenza hpylori e coli listeria proteus salmonella shigella |
|
|
amoxicillin + ampicillin + mononucleosis |
full body rash |
|
|
1st generation cephalosporins USES |
CEFAZOLIN CEPHALEXIN proteus e coli klebsiella |
|
|
2nd gen ceph |
Cefuroxime Cefaclor Cefoxitin Haemophilus influenza Enterobious Nistermis Serratia Protues Ecoli Klebsiela |
|
|
3rd gen ceph uses |
ceftraizone cefotaxime ceftazidime gram - (cetriaxone meinigitis ghonoora dissemtinated lyme disease) ceftazidime psuedonmas |
|
|
4th gen |
cefepime Psuedomas |
|
|
5th gen |
Cetaroline MRSA |
|
|
moa reistance against cephalosporins |
change in transpeptidases |
|
|
cilastin |
always give with impedenem
|
|
|
aztreonam moa |
gram- rods only binds to pencillin binding protein 3 s syngertic with ameinoglycocsides gram negative |
|
|
vancomycin |
nephrotoxic ototoxic thrombophlebitis diffuse flushignd ue to histamine release |
|
|
irrevesrible inhibition of intiaitla complex via 30s blcok translocation cause misreading of mrna require o2 |
aminoglycosides
bacterialcidal: Gentamicin Neomycin amikacin Tobramycin Streptomycin |
|
|
aminoglycosides mo reistansce |
bacterial trasnferase enzymes inactiave via aceytlation phosphrylation or adenylation |
|
|
aminoglycosides toxicity |
nephrotoxic neurmoustlc blockade ototoxic teratogen |
|
|
bind to 30 s and prevent attachment of aminoacyl t rna |
tetracyclines |
|
|
avoid using with antacides of milk or iron |
tetracyclines |
|
|
ues for teatraycclines |
borrelia burdgorefri mycoplasma pneumoniae rickestisa chlyamida acne |
|
|
reistancea gainst teracycliens |
paslmid ecoded transport pumps decreased influx or increased efflux |
|
|
block peptidyltransferase at 50s |
chorlamphenicol |
|
|
mo resistance against chlorampheincol |
plasmid encoded aceytal transferase |
|
|
risks of chloramphenicol |
anemia aplstic anemia gray baby syndrome (lack udp) |
|
|
clindamycin moa |
block 50 s translocaiton anaearobic infections above hte diaprhgam |
|
|
inhbiit 50 s initiaton complex |
linezolid |
|
|
mo resistance in linezolid |
point mutation of ribosomal rna |
|
|
mo resitance in macrolies |
methylation of 23 s r rna at 50 s |
|
|
block transloation by bidning to 23 s rna of 50 s rna inhibiting protein syntehsis |
macrolides erythromycin alrotihormycin azithromycine |
|
|
issues with macrolides |
motiliity issues, arrthemia via qt elogation choelstatic hepatitis rash eosiophilia increase contents of theophylins and clarithomycina dnerthrmycin inhibit cyp 450 |
|
|
inhibit dihydrofolate reductase |
trimethorprim methotretxate pymethaminde |
|
|
inhibit dihydroprteroate synthase |
dapsone sulfonamides |
|
|
inhbiit topo II and Iv |
flouroquinolones |
|
|
chormosome mediated dna gyrase utaiton plasmid meadiated reistanse and efflux pumps |
cloroquinone resistance |
|
|
daptomycin moa |
cell memebrane disurptoin |
|
|
daptomycin rsisks |
myopathy rhabdomylotitis |
|
|
metronidzole |
toxic free fradicas in bacterialc ell |
|
|
uses for metronidzole |
giardia enterobius trichimonas gardenella vaginallis anaareobes h ypolori |
|
|
rifampin moa |
inhibit dna depend rna polymrease orange body fluids |
|
|
isoniaizid moa |
inhibit mycolic acid syn but requires bacterial ctalase oxdiase |
|
|
pyraiznmide |
producg that causes hyperuriciemia hyepatox toxicity |
|
|
ehtambutol |
inhibit arabinosyltransferase optic neuroapthy |
|
|
tx for mrsa |
vancomycin daptomycin linezolid tigecycline cetaroline v |
|
|
vre tx |
lienzolid streptogramins quinupristin dalfopristin |
|
|
p. auergionas and acterinobactera buamanii |
poly myxisns b and e colistin |
|
|
amphotercin b |
binds to ergostoerl and forms holes in cell emembrane |
|
|
toxicities of amphotercin b |
hypotension nephrotixic arrythemais anemia iv phelmibitits hydration decreases and using liposomal version supplment k and mg |
|
|
cell membrane pores |
amphotercin b nystatin |
|
|
nucleic acid sytnehsis |
clycytosine via 5 clurocuracil conversion by ctosine daminase |
|
|
azoles |
inhibit cyp450 no conversion of lanosterol to ergosterol |
|
|
terbinafine |
inhibits squalene epoxidase |
|
|
enchincandinds |
-fungin ending |
|
|
inbhiitn cell wall sntehsis of beta glucan |
-fungin ending |
|
|
griseofulvin |
mt disruption despits in kertain containing itssues |
|
|
pyrmethamine use |
toxoplasmosis |
|
|
suramin and melarsoprol |
tyrpanosoma burcei |
|
|
nifrutimox |
trypanosoma cruzi |
|
|
sodium stibugluconate |
leshimaniasis |
|
|
permethirin moa |
lbock na |
|
|
malathion |
block ache |
|
|
lindane |
lbock gaba |
|
|
chlroquine |
prevent detoxiticaiton of heme into hemozoin causing toxi accumulations |
|
|
maraviroc |
prevents attachemtn |
|
|
enfurvitide |
prevent penetration |
|
|
integrase inhibitors |
raltegravir |
|
|
nnrtis |
delevirdine efavirenz nevirapine |
|
|
protease ihibitors |
atazanavir darunavir forsamprenavir indinavir lopinavi ritonavir sqauinavir |
|
|
nrtis |
abacavir diandonsine emtricitiabine lamivudine stavurdine tenofovoir sidzovuine |
|
|
oseltamiavir zanamavir |
inhibit NA |
|
|
guansoine analogs |
acyclovir famciclvoir valcyclcovir |
|
|
ganciclvoir |
5' monophostphate guanon sine analog for cMv |
|
|
foscarnet |
pyrophosphate |
|
|
3 regiment resmie of hiv |
2 nrtis and eiter 1 protease inhibitor 1 ingtegrase inhbiitor 1 nnrti |
|
|
interferon gamma |
cgd |
|
|
dont use in pregnancy
|
sulfonamides aminoglycocisdes fluroquinolones clarithoromycin tegracyclines ribavirin gresoefulvin hclorampheicol |
|
|
sporicidal |
hydrogen peroxide, idone, autoclave |
|
|
sofosbuvir |
inhibits hcv rna dependment rna polymerase dont use as monotherapy |
|
|
simeprevir |
hcv protease inhibitor |
|
|
ribavirin |
inhibit ysnethesis of guanine nucleotides by inhibiting IMP dehydrogenase |
|
|
amatoxin |
mushroom point aht inhibits RNA II no mrnas |
|
|
g6pd defiency |
isoaniazid sulfoanmides dapsone primiaquine asaprine iburpofen nitrofuraton |
|
|
weil felix test |
ricksetti |
