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76 Cards in this Set

  • Front
  • Back
c diff associated with
pseudomembrane colitis, secondary to clinda or amp use
tx of pseudomembrane colitis
metro, oral vanco
exotoxin inhibits protein synthesis by ADP ribosylation of EF-2
grey-white membrane in pharynx with LAD
tx: diphtheria antitoxin, DPT vaccine, penecillin
contact: malignant pustule
inhalation: flulike symptoms that rapidly progress to fever, pulmonary hemorrhage, shock
normal oral flora, bad if immunocompromised
neisseria gonococci cause
urethritis, cervicitis, PID, epididymitis
most common cause of septic arthritis
ophthalmia neonatorum- sticky eye discharge, tx- EES eye drops
H influ
epiglottitis, meningitis, otitis, pneumonia
can vaccinate
aerobic GN rods
e coli, salmonella, shigella, klebsiella, enterobacter, serratia, proteus
pneumonia, sepsis, UTI
red currant jelly sputum
motile, most common food associated diarrhea
do not tx- you will prolong the carrier state
see in chicken and eggs
bacterial dysentery- water diarrhea then mucousy diarrhea
S typhi
typhoid fever - fever, RUQ pain, resides in GB
S flexeneri
Reiter's syndrome
Yersinia entercolitica
pet feces (puppy)
seafood bugs
vibrio parahaemolyticus, v vulnificus
have sHIga like toxin - inhibits 60s ribosome
E coli general
diarrhea, UTI, neonatal meningitis/pneumonia/sepsis
most common cause of traveler's diarrhea
tx: TMP-SMX, fluoroquinolones
similar to cholera, rice water diarrhea
no intestinal wall invasion
O157:H7--> HUS- hemolysis, renal failure, TCP
similar to shigella
intestinal wall invasion- blood diarrhea and fever
bloody diarrhea
campylobacet, salmonella, shigella, EHEC, EIEC, yersinia enterocolitica, C diff, entamoeba
watery diarrhea
ETEC, vibrio, c perfringens, protozoa- giardia, cryptosporidium, viruses- rota, adeno, norwalk
campylobacter and cholera
comma shaped organisms
cAMP inducers
cholera, pertussus, e coli, bacillus
proteus mirabilis
very motile, flagella- no distinct colonies can be grown
common cause of UTI
carries urease (also h pylori and c neoformans)
cat scratch
dog/cat bite
pasteurella multocida
cat feces
animal urine
rat bites
spirillum minus
francisella tularemia
yersinia pestis
plague, prairie dogs
undulant fever, dairy products, contact with animals
poorly staining GN rod- use silver stain
aerosol transmission from environmental water source habitat
tx: ees
detect with urinary antigen test
pseudomonas causes
pneumonia (CF, immunocompromised), burn wound infections, UTI, external otitis, hot tub folliculitis, osteomyelitis (DM, IVDA), sepsis, endocarditis (IVDA), corneal infections in contact lens wearers
pseudomonas things
water source, produces endotoxin, blue green pigment
tx: AG + extended spectrum penicillin
H pylori
duodenal ulcers and gastric ulcers
tx with triple therapy
urease positive
gardnerella vaginalis
greenish vaginal discharge with fishy smell; nonpainful, tx with metro
clue cells
DDX granulomatous disease
fungal infections, silica/be exposure, tb, foreign bodies, sarcoid-hilar LAD, bartonella
primary tb
ghon complex, hilar nodes
secondary tb
fibrocaseous cavitary lesion- classic tb
how do we kill tb
kill by T memory lymphokines--> activate macrophages-->kill
Ghon complex
TB granulomas (Ghon focus) with lobar and perihilar lymph node involvement; reflects primary infection or exposure
tb symptoms
fever, night sweats, weight loss, hemoptysis
M kansasii
pulmonary tb like symptoms
M scrofulaceum
cervical LAD in kids
disseminated disease in AIDs
M marinum
marine activity, skin infection
M leprae
likes cool temperatures- infects skin and superficial nerves
Tx: l/t dapsone, rifampin
lepromatous leprosy
worse, failed cell mediated immunity
tuberculoid leprosy
self limited
lyme disease
caused by borrelia burgdorferi- transmitted by ixodes tick
erythema chronicum migrans rash with central clearing
tx: TCN, doxy
stage 1 lyme
erythema chronicum migrans, flulike symptoms
stage 2 lyme
neurologic and cardiac manifestations
stage 3 lyme
AI migratory polyarthritis
primary syph
painless chancre
secondary syph
disseminated disease with constitutional symptoms, maculopapular rash, condyloma lata, alopecia areata
tertiary syph
gumma, aortitis, neurosyph (tabes dorsalis- no proprioception), argyll robertson pupil
congenital syph
saber shins, saddle nodes, deafness, notched incisors, interstitial keratitis
argyll robertson pupil
accomodates to convergence but does not react to light
VRDL false positives
viruses (mono, hep), drugs, rheumatic fever/RA, lupus, leprosy
borrelia, leptospira, treponema
C pneumo and C psittaci
atypical pneumo- no fever or SOB, interstitial pneumo only
psittaci- avian resevoir
chronic infection, cause blindness in africa
urethritis, PID, ectopic pregnancy, neonatal pneumonia, neonatal conjunctivitis (tx with EES)
CT L1-L3
lymphogranuloma venereum
Rickettsia triad
HA, fever, rash, arthropod vector
tx for rickettsia
why is coxiella atypical
no rash, no vector, negative weil-felix reaction, aerosol
Q fever- interstitial pneumonia like woolsorters disease
rickettsia rickettsii- rash on palms and soles (migrates inward), HA, fever
endemic to east coast
peeling of palms and soles because of Hg poisoning
Endemic typhus (fleas)
R typhi
Epidemic typhus (human body louse)
R prowsezekii
Weil-Felix reaction
antirickettsia AB cross react with proteus antigen
Myco pneumo
atypical walking pneumonia (insidious onset, HA, nonproductive cough, diffuse interstitial infiltrate), high titer of cold agglutinins (IgM)
bacterial cell membrane contains cholesterol
younger patients in clusters