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5 Cards in this Set
- Front
- Back
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4 bacteria that produce IgA proteases.
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1. Neisseria meningitides
2. Streptococcus pneumoniae 3. Haemophilis influenzae 4. Neisseria gonorrhoeae |
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Describe how LPS exerts an effect.
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Acts on macrophages.
They release TNFalpha/other cytokines. These act on other cells causing release of PAF, kinins, leukotrienes, ROI, proteases, NO. Leading to host defense and shock. |
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Describe role of toll receptors.
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LPS interacts with TLR-4 which send signal to cell.
TLR-2 is assoc c other PAMPS. Gram neg: Think TLR-4 Gram pos: Think TLR-2. |
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Describe 3 types of exotoxins.
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1. Type 1 (superantigen:bind to surface.
2. Type 2. Phospholipases which make pore in cell membrane. 3. Type 3. ADP-ribosyl transferaes & zinc proteases. Have active and binding components; act against intracellular proein target. |
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3 most common causes of bacterial meningitis.
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1. neisseria meningitidis
2. hemophilus influenzae 3. strptococus pneumoniae. |
