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2 Cards in this Set
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- Back
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What does cross linking do?
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Basically, one antigen molecule is bound by several mIgs on the B cell. This results in a signal cascade initiated by the Igalpha/Igbeta co-stimulatory molecoles of BCR which upregulates MHC class II and B7 molecles so that the B cell can act as an antigen presenting cell for the T cell
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What are mitogens
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They are antigens that activate B cells without T cell hlep (LPS or polymeric antigens)
-Resulting in crosslinking of mIG that is sufficient to activate B cell to secrete IgM -However, no memory B cells produced |
