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21 Cards in this Set

  • Front
  • Back
Where are the cell body and synapse for the preganglionic neuron?
cell body - CNS
synapse- autonomic ganglia
Where are the cell body and synapse for the postganglionic neuron?
cell body - autonomic ganglia
synapse - target organ
Describe parasympathetic preganglionic neurons?
where are their cell bodies and synapses?
length of projections?
cell bodies - cranial and sacral regions of spinal cord
synapses - parasympathetic ganglia (in or near target organ)
long projections
Describe parasympathetic postganglionic neurons?
where are their cell bodies and synapses?
length of projections?
cell bodies - in parasympathetic ganglia
synapse - on target organ
short axonal projections
Describe sympathetic preganglionic neurons?
where are their cell bodies and synapses?
cell bodies - thoraco-lumbar region of spinal cord
synapse - paravertabral sympathetic chain
Describe sympathetic postganglionic neurons?
where are their cell bodies and synapses?
cellbodies - sympathetic chain
synapse- target organ
long axonal projections
Sympathetic effect on heart?
SA node?
AV node?
atrial muscle?
ventricular muscle?
what receptor?
SA - increase rate
AV - increase automaticity
Atrial muscle - increase force
Ventricular muscle - increase force & automaticity
Adrenegic beta 1
Parasympathetic effect on heart?
SA node?
AV node?
atrial muscle?
ventricular muscle?
what receptor?
SA - decrease rate
AV - decrease conduction velocity, AV block
Atrial muscle - decrease force
Ventricular muscle - no effect
Cholinergic M2
Sympathetic effect on arterioles?
constriction (alpha adrenegic)
except to muscle - dilation (adrenegic beta2)
Parasympathetic effect of arterioles?
no effect except on erectile tissue and salivary gland - dialation (cholinergic M3)
Sympathetic effect on veins
constriction - alpha
dilation - beta2
Parasympathetic efect of veins?
no effect
Sympathetic effect on eye (pupil and cilary muscle)?
pupil - dialte alpha
cilary muscle relaxs (slightly) beta
parasympathetic effect on eye (pupil and cilary muscle)?
constriction M3
sympathetic and parasympathetic effect on salivary gland?
symp - increase secreation alpha1, beta
parasymp - increased secreation, M3
what neurons release Ach?
All autonomic preganglionic neurons and postganglionic parasympathetic neurons (cholinergic transmission)
what neurons realese noradrenaline (NA)?
Most postganglionic sympathetic neurons (adrenic transmission)
homotropic transmitter release?
transmitter release dfrom neuron inhibits further release from same neuron
heterotropic transmitter release?
transmitter from a neuron inhibits release of a diffrent transmitter from a diffrent neuron
name 5 non-peptide and 4 peptide NANC transmitters?
non-peptide - ATP, NO, dopamine, GABA, 5-HT
peptide - NPY, VIP, GnRH, Substance P
What can co-transmitters do? (3)
1. increase the action of a transmitter
2. mediate a different phase of response
3. indirectly increase the action of a neuro transmitter