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24 Cards in this Set
- Front
- Back
- 3rd side (hint)
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phenylephrine
-which receptor? -actions |
-alpha 1 agonist
-dilate pupils, vasoconstriction, nasal decongestion |
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Clonidine
-which receptor -action |
-alpha 2
-agonist |
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Terbutaline
-which receptor -action -what other drug has the same action? |
-beta 2
-agonist -albuterol |
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amphetamines
-what kind of drugs -action -what other drug has the same mechanism? |
-indirect sympathomimetics
-induce release of NE -what does the NE do? -tyramine |
-activates alpha and beta adrenoreceptors
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atropine
-MoA -blocks what? -SE? |
-muscarinic antagonist
-blocks salivation, lacrimation, urination, defacation -SE: increase temp, dry mouth/skin,flushed skin, acute angle-closure glaucoma, disorientation |
-blocks SLUD
-SE: hot as a hare, dry as a bone, red as a beet, blind as a bat, mad as a hatter |
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pyridostigmine
-MoA -use |
-anticholinesterase- increase endogenous Ach
-myasthenia gravis, does not penetrate CNS |
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alpha blocker:phenoxybenzamine/phentolamine
-selective? -use? -toxicity? |
-non-selective
-use: pheochromocytoma -toxicity: orthostatic hypotension, reflex tachycardia |
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alpha blocker
-prazosin, terazosin, doxazosin -selectivity? -use? -toxicity? |
-alpha 1 receptors
-HTN, urinary retention in BPH -first dose orthostatic hypotension, dizziness, HA |
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alpha blocker
-mirtazapine -selectivity: -use -toxicity |
-alpha 2
-depression -sedataion, increase serum cholesterol, increases appetite |
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beta blockers
-beta 1 selective |
acebutelol
betaxolol esmolol atenolol metoprolol |
A BEAM of beta 1 blockers
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beta blockers
-non-selective |
beta 1 = beta 2
-propranolol, timolol, nadolol, pindolol, labetalol |
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beta blockers effects
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-decrease CO, decrease renin (for what?)
-decrease HR, contractility, decrease O2 consumption -decreases mortality for what? -decrease AV conduction velocity- which drugs? -slows progression of what disease? -decrease excretion of aqueous humor |
-HTN
-angina -MI -SVT- propranolol, esmolol -CHF -glaucoma |
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beta blockers SE
-use with caution in which pts? |
-impotence, exacerbate asthma, bradycardia, AV block, sedation, sleep alterations
-diabetes |
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apha 1 receptor
-what fxns? |
-increase vasc smooth muscle contraction
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alpha 2 receptor
-fxn |
decrease sympa outflow, decrease insulin release
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beta 1 receptor
-fxn |
-increase HR
-increase contractility, -increase renin release -increase lipolysis, -increase aqueous humor formation |
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beta 2 receptor
-fxns |
-vasodilation
-bronchodilation -increase glucagon release |
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M1 receptor
M2 receptor M3 receptor |
-CNS
-decrease HR -increase exocrine gland secretion |
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D1 receptor
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-relax renal vascular smooth muscle
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D2 receptor
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-modulates transmitter release (brain)
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H1 receptor
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-increase nasal/bronchial mucus production
-contraction of bronchioles -pruritis -pain |
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H2 receptor
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-increase gastric acid secretion
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V1 receptor
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-increase vascular smooth muscle contraction
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V2 receptor
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-increase H2O permeability and reabsorption in the collectng tubules of the kidney
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