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51 Cards in this Set
- Front
- Back
Bethanechol |
muscarinic agonist |
|
Carbachol |
muscarinic agonist |
|
methacholine |
muscarinic agonist |
|
pilocarpine |
muscarinic agonist |
|
Donepezil |
Anticholinesterase (indirect agonist) |
|
Galanatmine |
Anticholinesterase (indirect agonist) |
|
Rivastigmine |
Anticholinesterase (indirect agonist) |
|
Edrophonium |
Anticholinesterase (indirect agonist) |
|
Neostigmine |
Anticholinesterase (indirect agonist) |
|
Physostigmine |
Anticholinesterase (indirect agonist) |
|
Pyridostigmine |
Anticholinesterase (indirect agonist) |
|
Drug for sjogren's pt that is very dry (potent stimulator of sweat, tears, saliva) Also for open angle and closed angle glaucoma |
Pilocarpine |
|
Activates bowels and bladder |
Bethenecol |
|
Acetylcholinesterases used in alzheimers |
Rivastigmine, Galantamine, Donepezil |
|
Dx of Myasthenia Gravis (extremely short acting) Myasthenia now dx by anti-achR antibody test |
Edrophonium |
|
Post-op reversal of nmj blockade to get bowels and bladder going again; No CNS penetration |
Neostigmine |
|
Atropine OD |
Physostigmine |
|
Tx of myasthenia gravis, does not penetrate CNS |
Pyridostigmine |
|
which autonomic drugs exacerbate COPD, Asthma, peptic ulcers? |
cholinomimetics |
|
most fatal side effect of cholinomimetics and antidote |
1.excitation- you can stop breathing from xs excitation of diaphragm 2. atropine |
|
Regenerates AchE in case of toxicity by ache inhibitors |
pralidoxime |
|
Atropine Benztropine homatropine |
Muscarinic Antagonist |
|
Tropicamide |
Muscarinic Antagonist |
|
Dicyclomine, Hyocyamine |
Muscarinic Antagonist |
|
Glycopyrrolate |
Muscarinic Antagonist |
|
Ipratropium, Tiotropium |
Muscarinic Antagonist |
|
Oxybutynin |
Muscarinic Antagonist |
|
Solifenacin |
Muscarinic Antagonist |
|
Tolterodine |
Muscarinic Antagonist |
|
Scopolamine |
Muscarinic Antagonist |
|
Use for eye exams |
Tropicamide |
|
Use for Parkinson's Dz |
Benztropine |
|
Used pre-op to reduce airway secretions or orally to tx peptil ulcer |
glycopyrrolate |
|
Tx of COPD |
ipratropium, tiotropium |
|
reduces bladder spasm and urge urinary incontinenece |
oxybutynin, solifenacin, tolterodine |
|
treats motion sickness (CNS) |
scopolamine |
|
Action of Muscarinic antagonists |
inhibit parasymp action at M receptos M1-brain M2-heart M3-everything else decreases secretions, motility, mydriasis |
|
What does Epi effect more and when? |
a1,a2,b1,b2 b>a alpha predominates at high doses |
|
receptor for increased renin release |
b1 |
|
receptor for increased lipolysis |
b1 and 2 |
|
receptor for decreased lipolysis |
a2 |
|
receptor for mydriasis |
a1 |
|
receptor for increased intestinal and bladder muscle contraction |
a1 |
|
receptor for ciliar muscle relaxation |
b2 |
|
receptor for decreased uterine tone (tocolysis) |
b2 |
|
receptor for decreased sympathetic outflow, decreased aqueous humor production |
a2 |
|
receptor that relaxes renal vascular smooth muscle |
d1 |
|
phenoxybenzine |
irreversible a blocker |
|
use of phenoxybenzamine |
pheochromocytoma preop to prevent catecholamine hypertensive crisis |
|
phentolamine |
reversible a blocker |
|
use of phentolamine |
give to pts on MAO inhibitors who eat tyramine containing foods |