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9 Cards in this Set

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What is autism?
Impairment in reciprocal social interaction - self-absorption, lack of affective contact, avoidance of eye contact, disinterest in others

Non-communicative speech
Repetitive, bizzare beahvior
Deviant development
NO hallucinations or delusions
Lower intelligence
Some show scatter of strengths and unusual capabilities
Children with MR can be autistic as well
What is the prevalence of autism?
1 in 50
What is the etiology of autism?
Genetics and biology -- No evidence of psychosocial or parenting causes, but dysfunctional parents can impede attainment of ultimate development potential
Describe the genetic component of the etiology of autism as far as twin (MZ, DZ) and siblings.
Concordance between 36% of MZ twins and 0% between DZ twins

50% chance of sibling attaining and 15% of autistic sibs have a learning disability

AR in some cases
What is the biological component of the etiology of autism?
-Difference in orbitofrontal lobe
-Delayed response to sound on MEG
-Autoantibodies to seratonin receptors
-decreased urine catecholamines, increased dopamine metabolism in CSF, increased serum seratonin
-seizures
-occalsional specific medical etiology - PKU, congenital rubella, fragile X
How do you dx autism?
-Good Hx
-Observation
-Assessment of language & cognitive skills
-Rule out audiology problems
-Difficult to dx mild cases
What are the treatment options for autism?
Therapeutic nurses -- work with children and parents to foster positive relationships & educate parents on how to manage the child
-Encouraging social relationships
-Special ed programs
-Promote adaptation, social relationships, and self-reliance
What medications can be used to manage the symptoms of autism.
-Psychotropic drugs to manage agression
-stimulants, TCA, clonidine for underlying ADHD
-Fenfluramine -- encourages self-stimulating behavior but has major SE's
-Naltrexone- to manage self-injury
-SSRI's & Risperidone for agression & self-injury
What is the outcome of autistic children?
-early intervention is best & seems helpful
-longterm outcomes vary --
1. higher functioning pts. and those with higher IQ's and supportive families have a better outcome
2. Others may require assisted living arrangements
3. Can learn about feelings and social interactions but may never feel "normal"