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13 Cards in this Set
- Front
- Back
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Atherosclerosis |
Formation of atheromas (fibrofatty plaque) in medium and large arteries |
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Formation of raised Plaque |
Fatty Streak Fibrofatty plaque Inflammatory response Platelets and monocytes adhere to lining Release GF and cytokines Recruit smooth muscle and fibroblasts Produces collagen Macrophages engulf lipid and cholesterol |
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Risk factors for atherosclerosis |
Smoking HTN Elevated cholesterol Diabetes Age Gender Obesity Lower socioeconomical status Ethnicity |
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Major Sites of atherosclerosis |
Heart (angina, MI, chronic heart failure, sudden cardiac death) Brain (stroke) Extremeties (caludacation, gangrene) Kidneys (chornic kidney failure) |
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Coronary arteries that supply the left ventricle |
left circumflex left anterior descending |
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Coronary arteries that supply the Right ventricle and the posterior side of the left |
Right coronary artery |
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Angina Pectoris |
Due to myocardial ischemia (fixed stenosis) |
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If an infarct involves full thickness of wall |
Transmural |
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If an infarct involves the inner half of the wall |
Subendocardial |
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Dysrythmias |
disturbances in electrical rhythms |
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Congestive Heart Failure/Cardiogenic shock |
too much muscle infarcted, cannot meet the demands of the body Results in back up congestion of blood to lungs and unadeguate blood to the rest of the body |
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Ventricular Rupture |
When infarcted zone cannot hold together it ruptures hemorrhage around heart and causes a compression of heart (tamponade)
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MI Complications |
LV aneurysm Chronic congestive heart failure |
