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14 Cards in this Set

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  • Back
Leukotrienes
chemical mediators of inflammation stored and released by mast cells; effects are similar to those of histamine
Methylxanthine
chemical derivative of caffeine; alternative bronchodilators, prescribed for persistent chronic asthma.
Dry powder inhaler (DPI)
device used to convert a solid drug to a fine powder for the purpose of inhalation
Chronic bronchitis
recurrent disease of the lungs characterized by excess mucus production, inflammation, and coughing
Chronic obstructive pulmonary disease (COPD)
generic term used to describe several pulmonary conditions characterized by cough, mucus production, and impaired gas exchange
Salmeterol (serevent) bronchodilator/ beta 2 adrenergic agonist
acts by selectively binding to the beta 2 adrenergic receptors in bronchial smooth muscles to cause bronchodialation. can prevent exercise induced bronchospasms. Better suited for tx of chronic asthma due to it's duration. onset 10-20mins, duration up to 12hrs.
Ipratropium Bromide (atrovent, combivent)
Bronchodilator/ anticholinergic
anticholinergic that causes bronchodilation by blocking cholinergic receptors in bronchial smooth muscle. also prescribed for chronic bronchitis and nasal congestion. onset 5-15 mins, duration 3-6 hrs. bitter taste, rinse mouth,
Beclomethasone (Beclovent)
Inhaled glucocorticoid
glucocorticoid, available thru aerosol inhalation (MDI) for asthma or as a nasal spray for allergic rhinitis. Acts by reducing inflammation, decreasing frequency of asthma attacks.
Zafirlukast (Accolate)
Leukotriene modifier
used for the prophylaxis of persistent, chronic asthma. Blocks leukotrine receptors in the airways. onset 1 wk. adverse effects most common HA.
aerosol
suspension of minute liquid droplets or fine solid particles suspended in a gas- delivers the drugs to their immediate site of action (immediate relief for bronchospasms)
bronchodilators
most commonly used for treating pulmonary disorders, stimulate beta 2 adrenergic receptors to dilate bronchioles
MDIs
use a propellant to deliver a mesuared dose of drug to the lungs during each breath. disadvantages- precise does received difficult to measure
for treatment of acute bronchoconstriction
beta-adrenergic agonists- activate both beta 1 and 2 receptors (severent)
leukotriene modifiers
oral medications approved for the prophylaxis of chronic asthma- reduce inflammation and ease bronchoconstriction