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26 Cards in this Set
- Front
- Back
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ED50
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Effective dose that gives sign of toxicity to 50% of those exposed
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NOEL
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No observable effects level
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TLV
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American Conference of Government Industrial Hygienists
Guidelines only Intent to protect nearly all workers Oldest and most comprehensive In 1968 OSHA adopted TLVs as their PELs |
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TLV-TWA
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Time weighted average based on 8 hour day
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TLV-C
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Ceiling
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TLV-STEL
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Short term exposure limit
Typically 15 minutes |
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Shock reaction
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Devastating reaction upon re-exposure
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Causation- Hill Criteria
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Strength of association
Dose response curve Time sequence Consistency Biological plausibility and coherence Confounders |
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Cohort Study
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Define exposure of risk, determine outcome or disease
Calculate relative risk |
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Sensitivity
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TP/(TP+FN)
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Specificity
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TN/(TN+FP)
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Positive Predictive Value
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TP/(TP+FP)
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Negative Predictive Value
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TN/(TN+FN)
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Alpha value
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Maximum acceptable probability of having false positive
Usually set at .05 |
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Parametric Tests
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T-tests and ANOVA
Numerical data with continuous range of values |
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Non-parametrical tests
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Categorical data
Chi-square Fisher Mantel-Haenszel McNemar Mann-Whitley Wilcoxon |
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London 1973
Cleveland Clinic 1929 Belgium 1930 Coconut Grove 1942 Donora, PA 1948 |
London 1973 smog
Cleveland Clinic 1929 NO2,CO,CN Coconut Grove CO,CN Salerno CO Donora Smog |
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Devonshire 1700s
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Devonshire 1700 contaminated cider- lead
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France 1825
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Arsenious acid
Polyneuropathy |
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Japan 1939-1954
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Cadmium Itai-Itai
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Hexachlorobenzene
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Turkey 1956
Porphyria cutanea tarda |
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Minimata Bay
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Methylmercury 1950s
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Epping, England
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Methylenediamine
Epping Jaundice |
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Rice oil disease
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Japan(also Yu cheng in Taiwan)
1968 polychlorinated biphenyls |
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Polybrominated biphenyls
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Michigan 1973
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Denatured Rape seed oil
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Toxic oil syndrome
Madrid |
