Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
How does 1st generation Penicillin work?
|
First-penicillin must get inside bacteria
|
|
|
How does 2nd generation Penicillin work?
|
Second-find penicillin binding protein
|
|
|
How does 3rd generation Penicillin work?
|
Third-bind with protein, resulting in interference with normal cell wall synthesis
|
|
|
Common Side effects of Penicillin
|
N/V/D
Anxiety Abdominal pain Less common convulsions Allergic reactions-rash, fever |
|
|
Interventions for Penicillin
|
Interventions include: Check to make sure the client is not allergic to PCN; obtain culture before first dose of medication; increase fluid intake; and contact physician, if develop rash.
|
|
|
What are Cephalosporins?
|
Semi-synthetic antibiotic derivatives of a fungus
Structurally and pharmacologically similar to penicillin Kills bacteria= Bactericidal Broad spectrum Depending upon generation |
|
|
What are 1st generation Cephalosporins: Cefazolin
Ancef &Kefzol are used for? |
Surgical prophylaxis
Good gm+ coverage Poor gm- coverage |
|
|
The route for 1st generation Cephalosporins: Cefazolin
Ancef &Kefzol? |
IV & IM
|
|
|
What are 1st generation Cephalosporins: Cephalexin
Keflex & Keftab are used for? |
URI’s, otitis media,
Similar coverage as Cefazolin |
|
|
The route for 1st generation Cephalosporins: Cephalexin
Keflex & Keftab? |
PO
|
|
|
The route for 2nd generation Cephalosporins: Cefoxitin
Mefoxin? |
IV & IM
|
|
|
The use for 2nd generation Cephalosporins: Cefoxitin
Mefoxin? |
Good gm +/- coverage
and anaerobes |
|
|
The route for 2nd generation Cephalosporins: Cefuroxime
Kefurox & Zinacef? |
IV & IM
|
|
|
The use for 2nd generation Cephalosporins: Cefuroxime
Kefurox & Zinacef? |
Pneumonia and surgical prophylaxis
|
|
|
The route for 2nd generation Cephalosporins: Ceftin?
|
PO
|
|
|
The use for 2nd generation Cephalosporins: Ceftin?
|
Pneumonia and surgical prophylaxis
|
|
|
The route & use for 3rd generation Cephalosporins: Cefixime (Suprax)?
|
Only oral third generation
Suprax has structural changes to allow for better oral absorption Best of currently available oral ceph’s against gm-’s Tablet and suspension |
|
|
The route & use for 3rd generation Cephalosporins: Ceftriaxone (Rocephin)?
|
IV & IM; with long half life; can give daily
Highly protein bound (93—96 %) Easily passes meninges and diffuses into CSF Good gm- and some gm+ coverage |
