Appleton & Lange Review Of Pharmacy 2004

Front 1

Drug(s) indicated for controlling hyperuricemia

Back 1

Allopurinol (Zyloprim)

*not colchicine b/c it is indicated for the chronic management of gout

Front 2

Vitamin B6 interaction with Levadopa

Back 2

Pyridoxine, vitamin B6, in doses as low as 10 mg/day, can accelerate the rate of aromatic amino acid decarboxylation, thus increasing the peripheral conversion of levodopa to dopamine.

Front 3

Active ingredients in Mylanta

Back 3

Aluminum Hydroxide
Magnesium Hydroxide
Simethicone

Front 4

Which is more potent, amniophylline or theophylline?

Back 4

Aminophylline is the ethylenediamine salt of theophylline, and therefore has only 85% of the potency.

Front 5

Pharmacokinetics of a two-compartment model when administering IV bolus

Back 5

1. faster initial distribution than elimination
2. two slopes will be present when graphed

Front 6

Acceptable lubricants for condoms or diaphragm

Back 6

1) water-base lubricant (KY jelly)
2) spermicidal cream
**not oil-base (white vaseline, petrolatum)

Front 7

Clozapine should not be initiated in patients with what baseline WBC or ANC?

Back 7

WBC <3500/mm3
ANC <2000/mm3

Front 8

Clozapine should be discontinued in patients with what WBC or ANC?

Back 8

WBC <2000/mm3
ANC <1000/mm3

(do not rechallenge)

Front 9

Examples of standard amino acid solution for TPN

Back 9

Aminosyn
FreAmine

(NephrAmine is used for pts with renal impairment)

Front 10

Normal chloride level

Back 10

95-105mEq/L

Front 11

Contents of MTE-4 & MTE-5 solution?

Back 11

trace elements:
1. chromic chloride
2. Cupric sulfate
3. Manganese sulfate
4. Zice sulfate
(MTE-5): selenium

Front 12

What trace elements is seldomly present in a solution of multi-trace element?

Back 12

iron

Front 13

Dosage form of methotrexate

Back 13

tablet
powder for injection
solution for injection

Front 14

Side effect of ACEI

Back 14

dry cough
hypotension (first few days)
increase alertness
mood elevation

Front 15

Indication of verapamil

Back 15

Angina
Atrial fibrillation
Atrial flutter
Hypertension
Treatment & Prophylaxis of PSVT

Front 16

What is the rate-limiting step of drug absorption, disintegration time or dissolution time?

Back 16

dissolution time

Front 17

What is Zollinger-Ellison syndrome?

Back 17

Pathologic hypersecretory condition that may be caused by adenomas of the gastrin-producing islet cells of the pancreas. Patients with this condition experience persistent ulcer pain and diarrhea. The drug of choice for this is considered to be proton pump inhibitors such as omeprazole

Front 18

What is polyvinyl alcohol use for in ophthalmic solutions?

Back 18

viscosity builder to increase the contact time of the ophthalmic solution with the surface of the eye

Front 19

Ocupress

Back 19

Carteolol

(BB, decrease output of aqueous humor)

Front 20

What is EDTA, or ethylenediaminetetraacetic? acid

Back 20

Chelating agent that has the ability to remove trace quantities of metals that might promote the decomposition of the active drug.

Front 21

Brand names of enteric-coated aspirin

Back 21

Ecotrin
Easprin
Ascriptin Enteric

Front 22

Brand name of hydrochlorothiazide?

Back 22

HydroDiuril
Oretic
Microzide
Esidrix
Ezide
HydroKraft
Zide
HCT 50

Front 23

What does Dristan contain?

Back 23

aspirin
phenylephrine
chlorpheniramine
caffeine
(for common cold)

Front 24

What does Alka-Seltzer Plus contain?

Back 24

Phenylephrine
Chlorpheniramine
Dextromethorphan

(no asprin which is in Dristan, also used for treating common cold)

Front 25

Sular

Back 25

Nisoldipine

Front 26

Plendil

Back 26

Felodipine

Front 27

Dosage forms of ferrous sulfate?

Back 27

Feosol (caplet)
tablet
liquid drops
elixir
extended-release tablet
(not injectable due to local irritation, iron sucrose & iron dextran are injection)

Front 28

Sources of Vitamin B12

Back 28

Foods from animal sources such as eggs, dairy products, and especially liver contain vitamin B12. Another source is shellfish.
(strict vegetarians may require supplementation)

Front 29

Epsom salt

Back 29

Magnesium sulfate

(topical astringent)

Front 30

Betadine

Back 30

povidone-iodine

viruses, Gram - and Gram +
(topical antiseptic bactericide/virucide)

Front 31

How many ml is in a fluid ounce?

Back 31

30ml = 1 fl oz

Front 32

Percogesic

Back 32

Phenyltoloxamine citrate 30mg (antihistamine)/APAP 325mg

Front 33

Precription drugs effective for traveler's diarrhea?

Back 33

Fluoroquinolones (DOC)
Bactrim
Doxycycline

Front 34

Lyme disease is caused by what organism?

Back 34

spirochete Borrelia burgdorferi

DOC doxycycline, TCN
serious cases tx with IV ceftriaxone