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54 Cards in this Set

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Extrasylvian
Transcortical
Proposed by Wernicke

Language repetition not impaired
Pre-rolandic Extrasylvian
Motor Type 1
Motor Type 2
Post Rolandic Extrasylvian
Sensory Type 1
Sensory Type 2
Extrasylvian Motor Aphasia
Non fluent language

Good Comprehension

Preserved prosody, articulation, and grammar

Long latencies in language

Poor expressive language

Occasional Verbal paraphasia

Open questions are slow and incomplete.

Patient tends to repeat words included in the question.

Semi mutism , echolalia, preservation

Open questions are slow and incomplete
P
Extrasylvian motor type 1
left frontal lateral syndrome

Loss of verbal initiative

Dynamic aphasia
Extrasylvian Motor Aphasia 1

Basic Language Characteristics
Conversational Language - sparse , echolalic

Language Comprehension - relatively normal

Repetition - Good to normal

Pointing - Normal

Naming - mildly abnormal

Reading: Aloud - defective
Comprehension - normal

Writing - defective (motor act)
Associated Neurological Signs
Motor System - hemiparesis may exist (if motor damage), pathological reflexes

Articulation - normal

Cortical sensory function - normal

Praxis - normal

Visual field - Normal

Visual gnosis - Normal
Extrasylvian motor aphasia type 2

Associated Neurological signs
Supplementary motor area aphasia

Motor system - hemiparesis right leg

Articulation - mild defects

Cortical sensory function - right leg sensory loss

Praxis - Normal

Visual field - Normal

Visual gnosis - Normal
Extrasylvian Sensory Aphasia
good repetition
Fluent conversational language
Significant amount of verbal paraphasias and neologisms.

Empty speech
Patient repeats words and sentences presented by the examiner, regardless if they are incorrect and even in a foreign language
Extrasylvian Sensory Aphasia 1

Basic Language Characteristics
Conversational language - fluent paraphasic, echolalic

Language comprehension - defective

Repetition - Good to excellent

Pointing - defective

Naming - Defective

Reading: Aloud - may be perserved
Comprehension - defective

Writing - defective
Extrasylvian sensory aphasia 1
left temporal-occipital syndrome

Fluent spontaneous langauge, poor comprehension, good repetition.

Verbal paraphasias and neologisms

Defective comprehension

Defective naming but phonological cueing is effective
Extrasylvian Sensory Aphasia 2
angular and parietal occipital syndrome.

Some verbal amnesia
Fluent language, few paraphasias

Comprehension relativeley good

Good repetition

Significant word-finding difficulties

Gerstmann's syndrome - posterior occipital

(left angular gyrus)
Semantic Aphasia
an inability to simultaneously recognize the elements included in a sentence.

deficiencies in

Complex successive suborddinate clauses

reversible constructions (temporal and spatial)

double negatives

Comparative sentences

Passive constructions

constructions with transative verbs
Mixed Extrasylvian Aphasia
Spontaneous language is absent production virtually limited to repetition.

Echolalia

Articulation is good

Language understanding severely defective
Mixed Extrasylvian Aphasia
Basic language characteristics
Conversational language - nonfluent echolalia

Langage comprehension -defective

Repetition - relativeley good

Pointing - defective

Naming - Defective

Reading aloud - Defective
comprehension - defective

Writing - Defective
Mixed extrasylvian aphasia
Motor system - paresis, patholgical reflexes

Articulation - normal

Cortical sensory functin - often disordered

Praxis - may be defective

Visual field - Normal to defective

Visual gnosis- may be defective
Isolated syndrome
Mixed Extrasylvian aphasia

language area isolated from the rest of the brain
Non-cortical dysarthria-aphasia
Marie's quadrilateral space
Striato-capsular aphasia
Thalamic aphasia
White matter disease
the insula
cerebellar language disorders
Marie's quadrilateral space
Ventricle
Caudate
Putamen
Internal capsule
Thalamus

Dysarthria
Hypophonic speech

Aphemia - Broca's first name for aphasia in left frontal lobe/

Speech distubrances from damage to basal ganglia
Thalamic aphasia
Pulvinal (quasi-aphasia)

Mutism initially

Paraphasic hypophonic jargon

Anomia

Preserved repetition

Defective comprehension

(Parietal, Occipital)
White matter disease
multiple sclerosis - motor aphasic symptoms

Very rare

Nasal voice

Weak phonation

Variability of pitch

slow rate output
Subcortical Aphasia
Subcortical damage

Deep damage

19th century it was supposed that the insula was involved in language but when dejarine proposed the language area he did not include the insula.
Insular Aphasia
Dronkers analyzed 25 patients with defects in planning the speech articulatory movements , and 19 normal.

All of the first 25 patients and None of the 19 had damage to the insula .

Insula represents a crucial structure in the motor planning and organization of speech.
Cerebellar language disorders
It has been hypothesized that the cerebellum contribute to cognitive processing, particularly the processing of linguistic information. The cerebellum has anatmical connectiond to the cerebral cortex through which it can affect language function.

Neural cerebellar frontal loop - can affect cognitive linguistic functins.

Cerebellar damage has been associated with impaired grammar and decreased verbal fluency
Alexia
an acquired disturbance in reading;
a loss or impairment of the ability to comprehend written or printed language caused by brain damage
Dyslexia
a developmental disorder manifested by difficulty in learning to read despite conventional instruction, adequate intelligence, and sociocultural opportunity. it is dependent on fundamental cognitive disabilities which are frequently of constitutional origin
history

initial reports
valerius maximus=(CIRCA 30 AD): after his head was hit, a man lost the memory for letters

johann schmidt=(1673): loss of the reading ability with preserved writing ability
history
Dejerine: published in 1891 and 1892 two cases of alexia

in 1891 he described a patient with a vascular accident associated with mild anomia, right henianopia, and total inability to read and write (excepting his signature). A postmortem exam disclosed a left posterior parietal infarct

in 1892 Dejerine publishes the case of a patient unable to read, but without any other impairment in language, right hemianopia. he could normally write, but only read letters

-left occipital (mesial and inferior) infarct, involving the corpus callosum.
Alexia without agraphia
pure alexia, occipital alexia, agnostic alexia, posterior alexia, word-blindness, verbal alexia,

Dissassociation between ability to read and write

Letter by letter reading

Normal writing

Derivational (morphological) paralexias (taking -> Take)

Letter by letter reading may result in reading the word

Correct spelling

Ability to change the type of letter

Occipital left hemisphere
Alexia with agraphia
parietal-temporal, central alexia, literal alexia, aphasic alexia, letter blindness

Inability to read letters (total alexia)
Copy is better than spontaneous writing

Inability to change the type of letter

Reading other symbolic systems (e.g. , numbers) is also impaired.

Posterior parietal of left hemisphere
Spatial alexia
visuospatial alexia, neglect alexia

Asymmetric reading

Difficulties in the spatial recognition of letters

Left hemi-spatial neglect (most significant factor)

Completeing words

Inability to follow a text

Grouping and fragmenting

Neglect in reading - not 50/50
spatial alexia.

examples of some types of errors observed in reading

errors is reading letter, syllables, and words
1-errors in reading letters
h->n;
2-literal substitutions
fama->cama
3-syllables and pseudowords substitutions for words
tas->gas
4-letter additions
dentro->adentro
5-letter omissions
plazo->lazo
6-hemi-spatial neglect in reading words
soldado->dado
7-confabulation in words
bebe->contiene
8-word splitting
convertir->con ventir
spatial alexia.

examples of some types of errors observed in reading

errors is reading sentences and texts
1-hemi-spatial neglect in sentences
el hombre camina por la calle-> camina por la calle
2-word substitutions
las personas se reunen en el parque-> las personas se sientan en al parque
3-word addition
la cantina es de juan->la cantina es de don juan
4-word omissions
las personas se reunen en el parque-> las personas en el parque
5-confabulation in sentences
las personas se reunen en el parque->yo estuve en el parque
6-grouping
con tener-> contener
Frontal alexia
anterior alexia Broca aphasia

Broca's patients - such severe reading difficulty, has it's own classification.

Reading understanding is better than reading aloud.

Meaningul words

Errors are similar to spoken language errors

Aggramatic reading

Verbal reading better than literal reading. (easier to read words than letters)
Hemialexia
cutting the splenium of the corpus callosum without associated occipital damage.

Difficulties reading the information presented to the left visual field.
Special forms of alexia
Alexia for Braille in blind peoplr observed in cases of bilateral or right occipital lesions.

Kinesthetic alexia - inability to read following the letters with the fingers) with a normal visual reading has been reported in left parietal damage
Central alexias
The word is correctly recognized but there are defects in the semantic or phonologic processing of the word

Phonological alexia

Surface alexia

Deep alexia
Peripheral alexia
Defects in the correct recognition of the word

Letter by letter reading

Neglect alexia

Attentional alexia
Phonological alexia
Central alexia

Indirect route (phonological) impaired

Direct route (lexical) preserved

Inability to read pseudowords

Relative ability to read real words.

Frequency is crucial

Visual paralexias are frequent
Surface alexia
Indirect route (phonological) preserved.

Direct route (lexical) impaired

Reading regular words and pseudowords

Regularization of irregular words
Deep alexia
both routes are impaired and just some few residual abilities remain.

Semantic paralexias (lawyer->attorney)

Grammatical category and imaginability

Impossible to read pseudowords

Morphological (derivationsal) paralexias.

Aphasia and agraphia always observed.
Cross linguistic analysis of alexia
Patient can lose ability to read one language and not the other
(2 different language systems)

Kana - syllabic
Kanji- logographic

Even in 2 alphabetic systems
(Russian and French)

Even in the same alphabetic system (English and Spanish)

Chinese - not phonological
English
26 letters, over 30 phonemes

219 combinations of 24 consonants

342 possibilities for 13 vowels

Semantic paralexias common in English but not Spanglish
Agraphia
A loss or impairment in the ability to produce written language caused by brain pathology.

Linguistic defects (aphasic agraphias)

Non linguistic defects (e.g. motor or spatial) (non-aphasic agraphias)
Agraphia - History
Orgle (1867) - introduced the term agraphia

Exner (1881) - proposed a "writing center" (base of the second frontal gyrus, in front of the primary motor area of the hand)

Dejarine (1891) - described "alexia without agraphia" syndrome
* Assumed damage of primary motor are controlling hand movements caused writing problems"

Gertsman (1940) - proposed that agraphia can appear with acalculia right-left disorientation, and finger agnosia in a single syndrome (Gertsmann or angular gyrus syndrome)
Agraphia in Broca's Aphasia
Spoken output
sparse
effortful
poor articulation
short sentences
dysprosody
agrammatism
phonological paraphasias (error in speaking)
Agraphia in Broca's Aphasia
Written output
Sparse
Efforfful
Clumsy calligraphy
Abbreviated output
Agrammatism
Literal (substitutions of letters) paragraphias.
Agraphia in Broca Aphasia
Disorders in writing are clearly correlated with the fundamental linguisticc defect.

Writing is slow, clumsy, painstaking short and agrammatic.

Literal paragraphias due to anticipations (take->kake) , preservations (take->tate), and letter omissions, particularly iin syllabic clusters (glass->gass)

Calligraphy is poor
Agraphia in Broca Aphasia

2
Right hemiparesis

Patient has to use left hand in writing.

Change implies an additional problem.

Writing difficulties not the result of linguistic defects.
Agraphia in Wernicke Aphasia
impairment in writing ability
fluent writing
well formed letters
combined in inappropriate way.

Literal paragraphias - additions, substitutions, and ommissions of letters)

Verbal and neologistic paragraphias also found.

Written language deficit parallels the oral language defect.
Agraphia in Wernicke Aphasia 2
Grammatical elements are observed frequently

Grammatical elements overused.

Sentences may lack clear limits

Nouns may be under-represented (writing may be non understandable) jargonagraphia)
Agraphia in Wernicke Aphasia
Spoken Output
Normal articulation

Fluent

Normal phrase length

Normal prosody

Paragrammatism

Paraphasias
Agraphia in Wernicke Aphasia
Written Output
Normal calligraphy

Fluent

Normal sentence length

Paragrammatism

Paragraphias
Agraphia in Conduction Aphasia
Variable

Affterent motor agraphia (luria)

Literal paragraphias

Self-corrections (conduit d'approche)

Apraxic agraphia